Home Cart Sign in  
Chemical Structure| 22949-08-2 Chemical Structure| 22949-08-2

Structure of 22949-08-2

Chemical Structure| 22949-08-2

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 22949-08-2 ]

CAS No. :22949-08-2
Formula : C10H10N2O3
M.W : 206.20
SMILES Code : CC(N1CCC2=C1C=C([N+]([O-])=O)C=C2)=O
MDL No. :MFCD00022910
InChI Key :RLXSSISTKOLICZ-UHFFFAOYSA-N
Pubchem ID :258566

Safety of [ 22949-08-2 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H332-H335
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 22949-08-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 22949-08-2 ]
  • Downstream synthetic route of [ 22949-08-2 ]

[ 22949-08-2 ] Synthesis Path-Upstream   1~3

  • 1
  • [ 19727-83-4 ]
  • [ 22949-08-2 ]
YieldReaction ConditionsOperation in experiment
100% With triethylamine; acetyl chloride In tetrahydrofuran at 0 - 20℃; for 0.5 h; Step A: 6-Nitroindoline (3.0 g, 18.3 mmol) was dissolved in THF (45 mL) and Et3N (3.4 mL, 24.4 mmol) at O0C. Acetyl chloride (1.5 mL, 21 mmol) was added drop wise. The mixture was stirred at room temperature for 30 minutes. The mixture was partitioned between EtOAc and aqueous HCl. The organic layer was dried and concentrated to yield l-acetyl-6-nitroindoline (3.8 g, 100percent) as a yellow solid.
References: [1] Patent: WO2006/19831, 2006, A1, . Location in patent: Page/Page column 447.
[2] Zhurnal Obshchei Khimii, 1959, vol. 29, p. 2541,2550; engl. Ausg. S. 2504, 2511.
[3] Heterocycles, 1998, vol. 48, # 12, p. 2481 - 2484.
  • 2
  • [ 19727-83-4 ]
  • [ 108-24-7 ]
  • [ 22949-08-2 ]
References: [1] Heterocycles, 2005, vol. 65, # 8, p. 1939 - 1946.
[2] Chemical and Pharmaceutical Bulletin, 2005, vol. 53, # 10, p. 1277 - 1290.
[3] European Journal of Medicinal Chemistry, 2005, vol. 40, # 2, p. 167 - 172.
  • 3
  • [ 496-15-1 ]
  • [ 22949-08-2 ]
References: [1] European Journal of Medicinal Chemistry, 2005, vol. 40, # 2, p. 167 - 172.
[2] Heterocycles, 1998, vol. 48, # 12, p. 2481 - 2484.
[3] Zhurnal Obshchei Khimii, 1959, vol. 29, p. 2541,2550; engl. Ausg. S. 2504, 2511.
 

Historical Records

Technical Information

Categories