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Chemical Structure| 223763-91-5 Chemical Structure| 223763-91-5

Structure of 223763-91-5

Chemical Structure| 223763-91-5

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Product Details of [ 223763-91-5 ]

CAS No. :223763-91-5
Formula : C12H23NO3
M.W : 229.32
SMILES Code : OCC1(CNC(OC(C)(C)C)=O)CCCC1
MDL No. :MFCD20485947

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Application In Synthesis of [ 223763-91-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 223763-91-5 ]

[ 223763-91-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 24424-99-5 ]
  • [ 2239-31-8 ]
  • [ 223763-91-5 ]
YieldReaction ConditionsOperation in experiment
15.9 g With triethylamine; In tetrahydrofuran; at 20℃; To a stirred solution of [1-(aminomethyl)cyclopentyl]methanol (50.7 g) in THF (304 mL) was added triethylamine(60.2 mL) under ice-cooling. Di-tert-butyl dicarbonate (94.2 g) in THF (101 mL) was added dropwise to this solution.After the addition, the reaction mixture was stirred at room temperature overnight. The reaction mixture was diluted withwater and ethyl acetate, and the mixture was extracted with ethyl acetate. The organic layer was washed with saturatedsaline, dried over anhydrous sodium sulfate, and then the solvent was removed under reduced pressure. The residuewas extracted with ethyl acetate-hexane (1:9) (700 mL), and the extract was stirred at room temperature for 3 hours.Insolubles were collected by filtration, washed with hexane, and dried to afford the title compound (49.2 g). For thefiltrate, the solvent was removed under the reduced pressure, and the residue was purified by silica gel column chromatographyto afford the title compound (15.9 g).
 

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