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Chemical Structure| 22235-04-7 Chemical Structure| 22235-04-7

Structure of 22235-04-7

Chemical Structure| 22235-04-7

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Product Details of [ 22235-04-7 ]

CAS No. :22235-04-7
Formula : C10H7NO4
M.W : 205.17
SMILES Code : O=C(O1)C2=CC=C(NC(C)=O)C=C2C1=O
MDL No. :MFCD01156609
InChI Key :PFYOXMCPLCYYAQ-UHFFFAOYSA-N
Pubchem ID :11229489

Safety of [ 22235-04-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P280-P301+P312-P302+P352-P305+P351+P338

Application In Synthesis of [ 22235-04-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 22235-04-7 ]

[ 22235-04-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 253168-94-4 ]
  • [ 22235-04-7 ]
  • N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-5-yl)acetamide [ No CAS ]
  • 2-[1-(3-Ethoxy-4-methoxyphenyl)-2-metlylsutfonylethyl]-5-acetamidoisoindoline-1,3-dione [ No CAS ]
YieldReaction ConditionsOperation in experiment
20% EXAMPLE 13 2-[1-(3-Ethoxy-4-methoxyphenyl)-2-metlylsutfonylethyl]-5-acetamidoisoindoline-1,3-dione 2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-5-acetamidoisoindoline-1,3-dione was prepared by the procedure of Example 6 from 1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethylamine (1.0 g, 3.7 mmol) and 4-acetamidophthalic anhydride (751 mg, 3.66 mmol). The product was obtained as a yellow solid (330 mg, 20% yield): mp, 215.0-217.0 C.; 1 H NMR (DMSO-d6) delta 1.32 (t, J=6.9 Hz, 3H, CH3), 2.12 (s, 3H, CH3), 2.99 (s, 3H, CH3), 3.73 (s, 3H, CH3), 4.00 (q, J=7.0 Hz, 2H, CH2), 4.12 (dd, J=4.5, 14.3 Hz, 1H, CHH), 4.35 (dd, J=10.5, 14.2 Hz, 1H, CHH), 5.76 (dd, J=4.5, 10.5 Hz, 1H, NCH), 6.90-6.98 (m, 2H, Ar), 7.08 (br s, 1H, Ar), 7.83-7.84 (m, 2H, Ar), 8.19 (br s, 1H, Ar), 10.95 (br s, 1H, NH); 13 C NMR (DMSO-d6) delta 14.66, 24.22, 41.05, 47.35, 53.07, 55.47, 63.80, 111.74, 112.28, 112.72, 123.34, 124.59, 124.66, 129.74, 132.68, 145.00, 147.85, 148.84, 167.00, 167.28, 169.36; Anal Calcd for C22 H24 NO7 S: C, 57.38; H, 5.25; N, 6.08. Found: C, 57.13; H, 5.18; N, 5.74.
  • 2
  • [ 253168-94-4 ]
  • [ 22235-04-7 ]
  • N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-1,3-dioxoisoindolin-5-yl)acetamide [ No CAS ]
 

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