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Chemical Structure| 21728-28-9 Chemical Structure| 21728-28-9

Structure of 21728-28-9

Chemical Structure| 21728-28-9

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Product Details of [ 21728-28-9 ]

CAS No. :21728-28-9
Formula : C12H11NO3
M.W : 217.22
SMILES Code : O=C(OCC)/C=C1C(NC2=C\1C=CC=C2)=O
MDL No. :MFCD00474893

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Application In Synthesis of [ 21728-28-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 21728-28-9 ]

[ 21728-28-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 33105-81-6 ]
  • [ 1217-89-6 ]
  • [ 21728-28-9 ]
  • C32H33N3O4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
85% In methanol; at 30℃; for 12h; General procedure: Isatin (1, 0.20mmol, 1 equiv.), amino acid (2, 0.40 mmol, 2 equiv.), methyleneindolinone (3, 0.2mmol, 1 equiv.) and MeOH (0.2 mL or 1 mL) were well mixed and stirred at 30°C. Once the reaction was completed (monitored by TLC), the resulting residue was purified by flash column chromatography on silica gel to yield the corresponding product 4.
  • 2
  • [ 600-21-5 ]
  • [ 1217-89-6 ]
  • [ 21728-28-9 ]
  • C30H29N3O4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
84% In methanol; at 30℃; for 28h; General procedure: Isatin (1, 0.20mmol, 1 equiv.), amino acid (2, 0.40 mmol, 2 equiv.), methyleneindolinone (3, 0.2mmol, 1 equiv.) and MeOH (0.2 mL or 1 mL) were well mixed and stirred at 30C. Once the reaction was completed (monitored by TLC), the resulting residue was purified by flash column chromatography on silica gel to yield the corresponding product 4.
 

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