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Chemical Structure| 216393-56-5 Chemical Structure| 216393-56-5

Structure of 216393-56-5

Chemical Structure| 216393-56-5

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Product Details of [ 216393-56-5 ]

CAS No. :216393-56-5
Formula : C12H20OSSi
M.W : 240.44
SMILES Code : SC1=CC=CC(O[Si](C)(C(C)(C)C)C)=C1
MDL No. :MFCD01318115

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Application In Synthesis of [ 216393-56-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 216393-56-5 ]

[ 216393-56-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 216393-56-5 ]
  • [ 1158955-21-5 ]
  • C24H26FNO2SSi [ No CAS ]
YieldReaction ConditionsOperation in experiment
In 1-methyl-pyrrolidin-2-one; at 20℃; for 1h; Reference Example 34; 3-(3-Phenyl-1H-pyrazolo[3,4-b]pyridin-6-ylthio)phenol3-(Tertiary-butyldimethylsiloxy)thiophenol (548 mg, manufactured by Lancaster Chemical Corp.) was added to a solution of the Reference Example 30 (100 mg) in N-methylpyrrolidone (4.5 mL, manufactured by Kanto Chemical Co., Inc.), and the mixture was stirred for one hour at room temperature. Subsequently, hydrazine hydrate (73 μL, manufactured by Tokyo Chemical Industry Co., Ltd.) was added thereto, and the mixture was stirred overnight at the same temperature. Water (5 mL) was added to the reaction solution, and the mixture was extracted with chloroform (3×10 mL), washed with brine (10 mL), and dried (MgSO4). The solvent was then evaporated, to give 62.3 mg of the title compound. LC-MS: HPLC retention time 1.51 minutes, m/z (M+H) 320, condition C-1.
 

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