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Chemical Structure| 21578-58-5 Chemical Structure| 21578-58-5

Structure of 21578-58-5

Chemical Structure| 21578-58-5

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Product Details of [ 21578-58-5 ]

CAS No. :21578-58-5
Formula : C13H11N3
M.W : 209.25
SMILES Code : C1(NC2=NC3=CC=CC=C3N2)=CC=CC=C1

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Application In Synthesis of [ 21578-58-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 21578-58-5 ]

[ 21578-58-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 21578-58-5 ]
  • [ 1435-54-7 ]
  • N-phenyl-1H-benzimidazol-2-amine [ No CAS ]
YieldReaction ConditionsOperation in experiment
96.5% With potassium phosphate; In N,N-dimethyl acetamide; at 160℃; for 15h;Inert atmosphere; To 1 .00 g (3.94 mol) 1 ,3-dibromo-2-fluoro-benzene, 820 mg (3.94 mmol) N-phenyl-1 H- benzimidazol-2-amine and 2.51 g (1 1.8 mmol) potassium phosphate tribasic in 15 ml DMA are added, and it is stirred at 160 °C for 15 h under nitrogen. The reaction mixture is poured on water. The product is filtered off and washed with water. Yield 1.38 g (96.5 percent) 1H NMR (400 MHz, CDCI3): delta = 8.87 (d,1 H), 7.74-7.80 (m, 3H), 7.62-7.67 (m, 2H), 7.49-7.53 (m, 2H), 7.36-7.43 (m, 2H), 7.25-7.30 (m, 1 H), 7.18 (t, 1 H)
 

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