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Chemical Structure| 2131-62-6 Chemical Structure| 2131-62-6

Structure of 2131-62-6

Chemical Structure| 2131-62-6

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Product Details of [ 2131-62-6 ]

CAS No. :2131-62-6
Formula : C8H5NO2S
M.W : 179.20
SMILES Code : O=C(C1=CC=C(N=C=S)C=C1)O
MDL No. :MFCD00041369

Safety of [ 2131-62-6 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H315-H317-H319-H330-H334-H335-H351-H412
Precautionary Statements:P201-P202-P260-P264-P271-P272-P273-P280-P284-P302+P352-P304+P340+P310-P305+P351+P338-P308+P313-P333+P313-P337+P313-P403+P233-P405-P501
Class:6.1
UN#:2811
Packing Group:

Application In Synthesis of [ 2131-62-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 2131-62-6 ]

[ 2131-62-6 ] Synthesis Path-Downstream   1~6

  • 1
  • [ 2131-62-6 ]
  • [ 120-35-4 ]
  • 4-[3-(2-Methoxy-5-phenylcarbamoyl-phenyl)-thioureido]-benzoic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
Example 75 4-[3-(2-Methoxy-5-phenylcarbamoyl-phenyl)-thioureido]-benzoic acid Prepared according to the procedure described for Example 60 using 3-amino-4-methoxy-N-phenyl-benzamide (0.972 g, 4.0 mmol) and 4-carboxyphenyl isothiocyanate (0.722 g, 4.0 mmol) to afford the product (1.369 g); m.p. 201-202 C. Calculated for C22H19N3O4S.0.25 H2O: C, 62.03; H, 4.61; N, 9.87. Found: C, 61.92; H, 4.73; N, 9.59.
  • 2
  • [ 205744-17-8 ]
  • [ 2131-62-6 ]
  • N-(2-aminophenyl)-(4-(3-(6-fluoropyridine-3-yl)methyl)thioureido)benzamide [ No CAS ]
  • 3
  • [ 205744-17-8 ]
  • [ 2131-62-6 ]
  • 4-(3-((6-fluoropyridin-3-yl)methyl)thioureido)benzoic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
81% In tetrahydrofuran; at 20℃; for 12h; <strong>[205744-17-8]6-fluoro-3-aminomethylpyridine</strong> (133 mg, 1.06 mmol)And 4-isothiocyanobenzoic acid (189 mg, 1.06 mmol)Was dissolved in dry THF (10 mL)Reaction at room temperature for 12 hours,After the reaction, the solvent was evaporated to dryness to give 0.26 g of a yellow solid,Yield 81percent.
  • 4
  • [ 56622-54-9 ]
  • [ 2131-62-6 ]
  • N-(2-aminophenyl)-4-(3-((6-methylpyridin-3-yl)methyl)thioureido)benzamide [ No CAS ]
  • 5
  • [ 56622-54-9 ]
  • [ 2131-62-6 ]
  • C15H15N3O2S [ No CAS ]
  • 6
  • [ 30616-38-7 ]
  • [ 2131-62-6 ]
  • 4-(3-(3-(benzothiazol-2-yl)-4-hydroxyphenyl)thiourea)benzoic acid [ No CAS ]
YieldReaction ConditionsOperation in experiment
49% In acetonitrile; at 70℃; for 6h; General procedure: Compound 2 (0.200 g, 1.1 mmol or 0.100 g, 0.56 mmol)in CH3CN (15 mL) was added dropwise to a solution of 6(0.252 g, 1.1 mmol) or 7 (0.135 g, 0.56 mmol) in CH3CN(15 mL), respectively. The mixture was stirred for 6 h at 70 C.The precipitate was filtered and dried at ambient temperature.The obtained compounds were purified by columnchromatography eluted with acetone:MeOH (80:20 v/v).
 

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