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Chemical Structure| 205054-85-9 Chemical Structure| 205054-85-9

Structure of 205054-85-9

Chemical Structure| 205054-85-9

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Product Details of [ 205054-85-9 ]

CAS No. :205054-85-9
Formula : C10H13ClO2S
M.W : 232.73
SMILES Code : COC(OC)CSC1=CC(Cl)=CC=C1
MDL No. :MFCD21728591

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Application In Synthesis of [ 205054-85-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 205054-85-9 ]

[ 205054-85-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 205054-85-9 ]
  • [ 66490-20-8 ]
  • [ 66490-33-3 ]
YieldReaction ConditionsOperation in experiment
With phosphoric acid; In chlorobenzene; for 6h;Heating / reflux; A solution containing polyphosphoric acid (8 g) and chlorobenzene (50 mL) is heated at reflux. A solution containing 1-chloro-3-(2,2-dimethoxyethylsulfanyl)benzene (2.7 g, 11.6 mmol) in chlorobenzene (5 mL) is added dropwise to the refluxing polyphosphoric acid solution. After 6 hours, the solution is cooled to ambient temperature. The solution is diluted with CH2Cl2 and washed with water and saturated NaCl (aq.). The organic layer is dried over MgSO4, filtered and concentrated. The crude product is purified by column chromatography eluting with hexanes to yield the title compounds (2.4 g, 9.0 mmol) as a 1:1 isomeric mixture. 1H NMR (CDCl3, 300 MHz) δ7.88 (m, 1H), 7.75 (m, 2H), 7.42 (m, 2H). MS (EI): m/z 168, 170 (M+), Cl pattern
 

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