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Chemical Structure| 19961-27-4 Chemical Structure| 19961-27-4

Structure of 19961-27-4

Chemical Structure| 19961-27-4

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Product Details of [ 19961-27-4 ]

CAS No. :19961-27-4
Formula : C5H13N
M.W : 87.16
SMILES Code : CC(NCC)C
MDL No. :MFCD00015105
InChI Key :RIVIDPPYRINTTH-UHFFFAOYSA-N
Pubchem ID :88318

Safety of [ 19961-27-4 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H225-H314
Precautionary Statements:P210-P280-P305+P351+P338-P310
Class:3(8)
UN#:2733
Packing Group:

Application In Synthesis of [ 19961-27-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 19961-27-4 ]

[ 19961-27-4 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 78190-11-1 ]
  • [ 19961-27-4 ]
  • [ 953821-03-9 ]
YieldReaction ConditionsOperation in experiment
100% Reference Example 48 benzyl 3-[ethyl(isopropyl)amino]carbonyl}piperidine-1-carboxylate To a solution of <strong>[78190-11-1]1-[(benzyloxy)carbonyl]piperidine-3-carboxylic acid</strong> (3.00 g, 11.4 mmol) and DMF (2 drops) in THF (60 mL) was added oxalyl chloride (1.47 mL, 17.1 mmol) under ice-cooling, and the mixture was concentrated under reduced pressure after 1 hr. The obtained residue was dissolved in THF (60 mL), ethylisopropylamine (4.14 mL, 34.2 mmol) was added under ice-cooling, and the mixture was stirred for 30 min. The solvent was evaporated under reduced pressure, ethyl acetate was added to the residue, and the mixture was washed with 1N hydrochloric acid, 10% potassium carbonate and saturated brine, and dried over anhydrous sodium sulfate. The solution was purified by asic silica gel to give the title compound (3.79 g, quantitative). The compound was used for Reference Example 49 without purification.
 

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