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Chemical Structure| 1960-52-7 Chemical Structure| 1960-52-7

Structure of 1960-52-7

Chemical Structure| 1960-52-7

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Product Details of [ 1960-52-7 ]

CAS No. :1960-52-7
Formula : C8H6F3NO2
M.W : 205.13
SMILES Code : FC(C1=CC=C([N+]([O-])=O)C=C1C)(F)F
MDL No. :MFCD11226539
Boiling Point : No data available
InChI Key :NWCDDUFGSQYJRM-UHFFFAOYSA-N
Pubchem ID :10655830

Safety of [ 1960-52-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 1960-52-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1960-52-7 ]

[ 1960-52-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1960-52-7 ]
  • [ 106877-31-0 ]
YieldReaction ConditionsOperation in experiment
62% With iron; ammonium chloride; In methanol; water; at 60℃; for 3h; To intermediate 164b (15.0 g, 73.12 mmol, 1.00 equiv) in methanol/HiQ (100/25 mL) was added elemental Fe (15.0 g, 267.86 mmol, 3.66 equiv) and NH4C1 (1.5.0 g, 280.43 rnmol, 3.83 equiv) and the reaction was stirred at 60 C for 3 h. The mixture was filtered and the filtrate concentrated, diluted with 200 mL of ethyl acetate, washed with 2 x 100 mL of brine, dried over sodium sulfate and then concentrated to afford 8.0 g (62%) of intermediate 164c as a yellow oil.
 

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