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Chemical Structure| 195387-08-7 Chemical Structure| 195387-08-7

Structure of 195387-08-7

Chemical Structure| 195387-08-7

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Product Details of [ 195387-08-7 ]

CAS No. :195387-08-7
Formula : C11H21NO4
M.W : 231.29
SMILES Code : O=C(OC)C(C)(C)CNC(OC(C)(C)C)=O
MDL No. :MFCD24445651

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Application In Synthesis of [ 195387-08-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 195387-08-7 ]

[ 195387-08-7 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 180181-02-6 ]
  • [ 18107-18-1 ]
  • [ 195387-08-7 ]
YieldReaction ConditionsOperation in experiment
100% In methanol; dichloromethane; at 0℃;Inert atmosphere; Under argon, to a solution of 3-([(fert-butoxy)carbonyl]amino)-2,2-dimethylpropanoic acid (CAS number [180181-02-6], 250 mg, 1.09 mmol) in DCM (6 mL) and MeOH (2 mL) was added, dropwise at 0C, (trimethylsilyl)diazomethane (819.86 mu, 1 .64 mmol) until yellow persistent color. Then AcOH was added until complete discoloration. The reaction mixture was concentrated in vacuo then diluted with H20 and extracted with DCM twice. The combined organic phases were washed with sat. brine, dried over MgS04, filtered and concentrated in vacuo to give 260 mg of compound 6 as a colorless oil (quant.).
 

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