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Chemical Structure| 19355-69-2 Chemical Structure| 19355-69-2

Structure of 19355-69-2

Chemical Structure| 19355-69-2

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Product Details of [ 19355-69-2 ]

CAS No. :19355-69-2
Formula : C4H8N2
M.W : 84.12
SMILES Code : CC(C#N)(N)C
MDL No. :MFCD00043024

Safety of [ 19355-69-2 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301-H315-H317-H318-H335
Precautionary Statements:P261-P264-P270-P271-P272-P280-P302+P352-P304+P340-P305+P351+P338-P310-P330-P332+P313-P362-P403+P233-P405-P501
Class:6.1
UN#:2810
Packing Group:

Application In Synthesis of [ 19355-69-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 19355-69-2 ]

[ 19355-69-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 3029-64-9 ]
  • [ 19355-69-2 ]
  • [ 66308-91-6 ]
YieldReaction ConditionsOperation in experiment
With sodium hydroxide; In water; acetone; EXAMPLE IV 4,6-Dichloro-2-(1-cyano-1-methylethylamino)-5-pyrimidinecarbonitrile A stirred solution of 6.3 grams of <strong>[3029-64-9]2,4,6-trichloro-5-pyrimidinecarbonitrile</strong> in 25 ml of acetone was cooled to -10°, and 2.5 grams of 2-amino-2-methylpropionitrile was added. With the reaction mixture at -10°, a solution of 1.3 grams of sodium hydroxide in 3.5 ml of water was added dropwise. Upon complete addition, the reaction mixture was stirred at -10° for 30 minutes. The acetone was removed under reduced pressure; the residue was extracted with diethyl ether, and the extract was separated and dried over magnesium sulfate. The extract was filtered, and the filtrate was evaporated under reduced pressure, yielding a residue. The residue was recrystallized from methylcyclohexane to give 3.1 grams of 4,6-dichloro-2-(1-cyano-1-methylethylamino)-5-pyrimidinecarbonitrile; mp, 154-158°. Analysis: Calculated for C9 H7 Cl2 N5: C,42.21; H,2.73; N,27.34; Found: C,42.26; H,2.92; N,27.35.
 

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