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Chemical Structure| 193469-44-2 Chemical Structure| 193469-44-2

Structure of 193469-44-2

Chemical Structure| 193469-44-2

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Product Details of [ 193469-44-2 ]

CAS No. :193469-44-2
Formula : C12H15NO
M.W : 189.25
SMILES Code : O=C1CC(CC2=CC=CC=C2)NCC1

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Application In Synthesis of [ 193469-44-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 193469-44-2 ]

[ 193469-44-2 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 193469-44-2 ]
  • [ 34619-03-9 ]
  • [ 193480-28-3 ]
YieldReaction ConditionsOperation in experiment
100% In dichloromethane; at 20℃; for 48h; Di-tert-butyl dicarbonate (21.8 g) was added to a mixture of intermediate 1 (17 g) in CH2Cl2 (500 ml) and the mixture was stirred at RT for 48 hours. The mixture was evaporated, the residue was taken up in water and toluene and the organic layer was separated. The aqueous layer was extracted again with toluene. The combined organic layers were dried, filtered and evaporated, yielding 38 g (100%) of (+/-)-1,1-dimethylethyl 4-oxo-2-(phenylmethyl)-1-piperidinecarboxylate (intermediate 6).
  • 2
  • [ 193469-44-2 ]
  • [ 24424-99-5 ]
  • [ 193480-28-3 ]
YieldReaction ConditionsOperation in experiment
38 g (100%) In CH2Cl2 (500 mo); water; EXAMPLE A4 Di-tert-butyl dicarbonate (21.8 g) was added to a mixture of intermediate 1 (17 g) in CH2Cl2 (500 mo) and the mixture was stirred at RT for 48 hours. The mixture was evaporated, the residue was taken up in water and toluene and the organic layer was separated. The aqueous layer was extracted again with toluene. The combined organic layers were dried, filtered and evaporated, yielding 38 g (100%) of (+-)-1,1-dimethylethyl 4-oxo-2-(phenylmethyl)-1-piperidinecarboxylate (intermediate 6).
 

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