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Chemical Structure| 192725-17-0 Chemical Structure| 192725-17-0

Structure of Lopinavir
CAS No.: 192725-17-0

Chemical Structure| 192725-17-0

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Lopinavir (ABT-378) functions as a highly potent, selective peptidomimetic inhibitor of the HIV-1 protease, with Kis ranging from 1.3 to 3.6 pM for both wild-type and mutant HIV protease. Its action involves arresting maturation of HIV-1, thereby blocking its infectivity. Lopinavir also exhibits inhibition against SARS-CoV 3CLpro with an IC50 of 14.2 μM.

Synonyms: ABT-378; A-157378.0; Koletra

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Elgammal, Yehia ; Salama, Ehab A ; Seleem, Mohamed N ;

Abstract: Candida auris is an invasive fungal pathogen, representing a global public health threat. It is characterized by high mortality rates among infected individuals, significant antifungal resistance, and a remarkable ability to persist in healthcare environments. While amphotericin B is one of the most powerful antifungal agents for treating Candida infections, approximately 30% of C. auris isolates demonstrate resistance to it. Thus, the development of novel antifungal therapies is vital for tackling its life-threatening infections. In this study, we identified four HIV protease inhibitors (atazanavir, saquinavir, lopinavir and ritonavir) as strong potentiators of amphotericin B against C. auris. A synergistic effect between HIV protease inhibitors and amphotericin B was observed against 15 C. auris isolates with fractional inhibitory concentration index (FICI) ranging from 0.09 to 0.50. Additionally, the combinations between HIV protease inhibitors and amphotericin B showed fungicidal effect, significantly reducing the viable cell count in the time-kill assay within 6 hours. Furthermore, the combinations inhibited biofilm formation of C. auris by 60–75% and exhibited a remarkable suppression of C. albicans hyphae. The in vivo treatment with HIV protease inhibitors combined with amphotericin B resulted in a significant reduction of C. auris colony-forming units (CFU) by 1.7–2.6 Log10 in the C. elegans model. These findings suggest that HIV protease inhibitors, in combination with amphotericin B, are promising candidates for the development of novel antifungal drugs to treat Candida infections.

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Nour M. Alkashef ; Mohamed N. Seleem ;

Abstract: Cryptococcosis is a fungal infection that is becoming increasingly prevalent worldwide, particularly among individuals with compromised immune systems, such as HIV patients. Amphotericin B (AmB) is the first-line treatment mainly combined with flucytosine. The scarcity and the prohibitive cost of this regimen urge the use of fluconazole as an alternative, leading to increased rates of treatment failure and relapses. Therefore, there is a critical need for efficient and cost-effective therapy to enhance the efficacy of AmB. In this study, we evaluated the efficacy of the HIV protease inhibitors (PIs) to synergize the activity of AmB in the treatment of cryptococcosis. Five PIs (ritonavir, atazanavir, saquinavir, lopinavir, and nelfinavir) were found to synergistically potentiate the killing activity of AmB against Cryptococcus strains with ƩFICI ranging between 0.09 and 0.5 against 20 clinical isolates. This synergistic activity was further confirmed in a time-kill assay, where different AmB/PIs combinations exhibited fungicidal activity within 24 hrs. Additionally, PIs in combination with AmB exhibited an extended post-antifungal effect on treated cryptococcal cells for approximately 10 hrs compared to 4 hours with AmB alone. This promising activity against cryptococcal cells did not exhibit increased cytotoxicity towards treated kidney cells, ruling out the risk of drug combination-induced nephrotoxicity. Finally, we evaluated the efficacy of AmB/PIs combinations in the Caenorhabditis elegans model of cryptococcosis, where these combinations significantly reduced the fungal burden of the treated nematodes by approximately 2.44 Log10 CFU (92.4%) compared to the untreated worms and 1.40 Log10 ((39.4%) compared to AmB alone. The cost-effectiveness and accessibility of PIs in resource-limited geographical areas compared to other antifungal agents, such as flucytosine, make them an appealing choice for combination therapy.

Alternative Products

Product Details of Lopinavir

CAS No. :192725-17-0
Formula : C37H48N4O5
M.W : 628.80
SMILES Code : CC(C)[C@H](N1CCCNC1=O)C(N[C@H](C[C@H](O)[C@@H](NC(COC2=C(C)C=CC=C2C)=O)CC3=CC=CC=C3)CC4=CC=CC=C4)=O
Synonyms :
ABT-378; A-157378.0; Koletra
MDL No. :MFCD22628840

Safety of Lopinavir

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Isoform Comparison

Biological Activity

Target
  • HIV Protease

    HIV protease, Ki:1.3 pM

Clinical Trial:

NCT Number Conditions Phases Recruitment Completion Date Locations
NCT00661349 HIV Infections Phase 4 Terminated(It has been impossi... More >>ble to achieve the number of patients defined by protocol) Less << - Spain ... More >> Hospital Son Dureta Palma de Mallorca, Baleares, Spain, 07014 H.U. Germans Trias i Pujol - Unitat VIH, Fundació Lluita contra la Sida Badalona, Barcelona, Spain, 08916 Hospital General Universitario de Alicante Alicante, Spain, 03010 Hospital Clínic i Provincial de Barcelona Barcelona, Spain, 08036 Hospital Universitario Príncipe de Asturias Madrid, Spain, 28005 Hospital Clínico San Carlos Madrid, Spain, 28040 Hospital Universitario la Paz Madrid, Spain, 28046 Hospital Clínico de Salamanca Salamanca, Spain, 37007 Hospital Universitario de Valme Sevilla, Spain, 41014 Less <<
NCT00262522 Human Immunodeficiency Virus I... More >>nfections Less << Phase 3 Completed - -
NCT00105079 HIV Infections Phase 3 Completed - -
NCT00262522 - Completed - -
NCT00400738 HIV Infections Phase 2 Completed - Thailand ... More >> The HIV Netherlands Australia Thailand Research Collaboration Bangkok, Thailand, 10330 Less <<
NCT00266058 HIV Infections ... More >> Malaria Less << Phase 1 Completed - United States, California ... More >> San Francisco General Hospital San Francisco, California, United States, 94110 Less <<
NCT01453933 HIV Infection ... More >> Endothelial Dysfunction Less << Phase 4 Unknown December 2014 Netherlands ... More >> Onze Lieve Vrouwe Gasthuis Recruiting Amsterdam, Noord Holland, Netherlands, 1091 AC Contact: Guido van den Berk, MD, PhD       G.E.L.vandenBerk@olvg.nl    University Medical Center Utrecht Recruiting Utrecht, Netherlands, 3584CX Contact: Steven FL van Lelyveld, MD       s.f.l.vanlelyveld@umcutrecht.nl    Contact: Andy IM Hoepelman, MD, PhD       i.m.hoepelman@umcutrecht.nl    Sub-Investigator: Steven FL van Lelyveld, MD          Principal Investigator: Andy IM Hoepelman, MD, PhD Less <<
NCT00578825 Severe Acute Respiratory Syndr... More >>ome Less << Not Applicable Unknown - China ... More >> Department of Health Not yet recruiting Hong Kong, China Sub-Investigator: Wilina Lim, Dr          Kowloon Hospital Not yet recruiting Hong Kong, China Sub-Investigator: Thomas Mok, Dr          Prince of Wales Hospital Not yet recruiting Hong Kong, China Princess Margaret Hospital Not yet recruiting Hong Kong, China Sub-Investigator: ST Lai, Dr          Sub-Investigator: KL Au, Dr          Queen Mary Hospital Not yet recruiting Hong Kong, China The Chinese University of Hong Kong Not yet recruiting Hong Kong, China Sub-Investigator: Dennis Lo, Prof          Sub-Investigator: Christopher Lam, Prof          Sub-Investigator: David Hui, Prof          The University of Hong Kong Not yet recruiting Hong Kong, China Sub-Investigator: Malik Peiris, Prof          Sub-Investigator: Kenneth Tsang, Prof          Sub-Investigator: KY Yuen, Prof          Tuen Mun Hospital Not yet recruiting Hong Kong, China United Christian Hospital Not yet recruiting Hong Kong, China Less <<
NCT01083173 - Completed - -
NCT01294761 HIV Infections Not Applicable Completed - Japan ... More >> National Center for Global Health and Medicine Shinjuku, Tokyo, Japan, 1628655 Less <<
NCT00105079 - Completed - -
NCT00234910 HIV Infection Phase 3 Completed - United States, Illinois ... More >> Global Medical Information-Abbott Abbott Park, Illinois, United States, 60064 Less <<
NCT01576731 HIV Infection Phase 4 Completed - Spain ... More >> Hospital Clínic of Barcelona Barcelona, Spain, 08036 Less <<
NCT00772902 HIV-1 Phase 4 Completed - Austria ... More >> Gilead Sciences Vienna, Austria, 1220 Germany Gilead Sciences Munich, Germany Italy Gilead Sciences Milan, Italy Spain Gilead Sciences Madrid, Spain Less <<
NCT01083173 - Completed - -
NCT02581202 - Completed - Russian Federation ... More >> GUZ Altai Territory Ctr for Disease Prevention of AIDS /ID# 145685 Chelyabinsk, Russian Federation, 454038 Regional Centre for Disease Prevention and Control of AIDS /ID# 145687 Chelyabinsk, Russian Federation, 454038 GBUZ Regional Center for the Prevention and Control of AIDS /ID# 145697 Ekaterinburg, Russian Federation, 620102 State Budgetary Healthcare Institution /ID# 145689 Irkutsk, Russian Federation, 664035 Kaliningrad Reg Ctr for Disease Prevention of AIDS /ID# 145686 Kaliningrad, Russian Federation, 236006 Republican Center of AIDS profilactis Tatarstan /ID# 145684 Kazan, Russian Federation, 420097 KGUZ Regional Centre for Disease Prevention-Control of AIDS /ID# 145683 Krasnoyarsk, Russian Federation, 660049 Russian Federal AIDS Center /ID# 145692 Moscow, Russian Federation, 105275 Moscow Regional AIDS Center /ID# 145693 Moscow, Russian Federation, 129110 Orenburg Regional Clinical Infection Hospital /ID# 145695 Orenburg, Russian Federation, 460035 Center for Prevention and Control of AIDS " Rostov Region /ID# 145691 Rostov-on-Don, Russian Federation, 344006 Saint-Petersburg AIDS Center /ID# 145694 Saint-Petersburg, Russian Federation, 190103 The Republican Center for Prevention and Control of AIDS /ID# 145690 Ufa, Russian Federation, 450077 Less <<
NCT02369965 HIV Infections ... More >> AIDS Less << Phase 3 Unknown December 2016 China, Beijing ... More >> 302 Military Hospital of China Recruiting Beijing, Beijing, China Contact: Min Zhao          Principal Investigator: Min Zhao          Beijing Ditan Hospital, Capital medical university Recruiting Beijing, Beijing, China Contact: Hongxing Zhao          Principal Investigator: Hongxing Zhao          Beijing YouAn Hospital, Capital medical university Recruiting Beijing, Beijing, China Contact: Hao Wu          Principal Investigator: Hao Wu          China, Guangdong Guangzhou Eighth People's Hospital Recruiting Guangzhou, Guangdong, China Contact: Weiping Cai          Principal Investigator: Weiping Cai          Shenzhen Third People's Hospital Not yet recruiting Shenzhen, Guangdong, China Contact: Hui Wang          Principal Investigator: Hui Wang          China, Henan Henan Infectious Disease Hospital Recruiting Zhengzhou, Henan, China Contact: Qingxia Zhao          Principal Investigator: Qingxia Zhao          China, Hunan The First Hospital of Changsha Recruiting Changsha, Hunan, China Contact: Min Wang          Principal Investigator: Min Wang          The Second Xiangya Hospital of Central South University Not yet recruiting Changsha, Hunan, China Contact: Yuhuang Zheng          Principal Investigator: Yuhuang Zheng          China, Liaoning Dalian Sixth People's Hospital Not yet recruiting Dalian, Liaoning, China Contact: Zhenxing Cui          Principal Investigator: Zhenxing Cui          China, Shanghai Shanghai Public Health Clinical Center Recruiting Shanghai, Shanghai, China Contact: Hongzhou Lu          Principal Investigator: Hongzhou Lu          China, Shanxi Tangdu Hospital of the Forth Military Medical University Recruiting Xi'an, Shanxi, China Contact: Yongtao Sun          Principal Investigator: Yongtao Sun          China, Zhejiang The First Affiliated Hospital of College of Medicine, Zhejiang University Not yet recruiting Hangzhou, Zhejiang, China Contact: Jifang Sheng          Principal Investigator: Jifang Sheng Less <<
NCT00571961 HIV Infections Not Applicable Completed - United States, Connecticut ... More >> Yale University School of Medicine New Haven, Connecticut, United States, 06520 Less <<
NCT00700115 HIV Infections Phase 4 Completed - United States, Georgia ... More >> Grady Infectious Diseases Program (Ponce Clinic) Atlanta, Georgia, United States, 30308 Less <<
NCT00700115 - Completed - -
NCT00720590 Endothelial Dysfunction Not Applicable Completed - United States, Indiana ... More >> Indiana University School of Medicine Indianapolis, Indiana, United States, 46202 Less <<
NCT00335686 HIV Infections Phase 4 Completed - Spain ... More >> Hospital C. Universitario de Santiago Santiago, A Coruña, Spain, 15706 Hospital General Universitario de Elche Elche, Alicante, Spain, 03203 Hospital Can Mises Ibiza, Baleares, Spain, 07800 Hospital Universitari Germans Trias i Pujol Badalona, Barcelona, Spain, 08916 Hospital de Granollers Granollers, Barcelona, Spain, 08400 Mutua de Terrassa Terrassa, Barcelona, Spain, 08221 Hospital General de Castellón Castello, Castellón, Spain, 12004 Hospital de Figueres Figueres, Girona, Spain, 17600 Hospital de Palamós Palamós, Girona, Spain, 17230 Hospital Virgen del Toro Mahón, Menorca, Spain, 07701 Hospital Nuestra Señora del Rosell Cartagena, Murcia, Spain, 30071 Hospital C. Universitario Virgen de la Victoria Malaga, Málaga, Spain, 29010 Hospital Costa del Sol Marbella, Málaga, Spain, 29600 Hospital Central de Asturias Asturias, Oviedo, Spain, 33006 Hospital Sant Joan de Reus Reus, Tarragona, Spain, 43201 Hospital General Universitario de Alicante Alicante, Spain, 03010 Hospital de Sant Pau Barcelona, Spain, 08025 Hospital de Mataró Barcelona, Spain, 08304 Hospital C. San Carlos Madrid, Spain, 28040 Hospital Marqués de Valdecilla Santander, Spain, 39008 Hospital Universitario Joan XXIII de Tarragona Tarragona, Spain, 43007 Hospital Clínico de Valencia Valencia, Spain, 46010 Hospital Arnau de Vilanova Valencia, Spain, 46015 Hospital Xeral Cies de Vigo Vigo, Spain, 36204 Less <<
NCT00038480 HIV Infections Phase 1 Completed - United States, California ... More >> Children's Hosp. & Research Ctr. Oakland, Ped. Clinical Research Ctr. & Research Lab. Oakland, California, United States, 94609-1809 UCSF Pediatric AIDS CRS San Francisco, California, United States, 94143-0105 United States, Colorado Univ. of Colorado Denver NICHD CRS Aurora, Colorado, United States, 80218-1088 United States, District of Columbia Children's National Med. Ctr. Washington DC NICHD CRS Washington, District of Columbia, United States United States, Florida Univ. of Florida Jacksonville NICHD CRS Jacksonville, Florida, United States, 32209 USF - Tampa NICHD CRS Tampa, Florida, United States United States, Illinois Chicago Children's CRS Chicago, Illinois, United States, 606143394 United States, Maryland Univ. of Maryland Med. Ctr., Div. of Ped. Immunology & Rheumatology Baltimore, Maryland, United States, 21201 Johns Hopkins Hosp. & Health System - Dept. of Peds., Div. of Infectious Diseases Baltimore, Maryland, United States, 21287 United States, Massachusetts Children's Hosp. of Boston NICHD CRS Boston, Massachusetts, United States, 021155724 Baystate Health, Baystate Med. Ctr. Springfield, Massachusetts, United States, 01199 United States, New York Bronx-Lebanon Hosp. IMPAACT CRS Bronx, New York, United States, 10457 United States, Pennsylvania St. Christopher's Hosp. for Children Philadelphia, Pennsylvania, United States United States, Tennessee St. Jude/UTHSC CRS Memphis, Tennessee, United States, 381052794 Brazil SOM Federal University Minas Gerais Brazil NICHD CRS Minas Gerais, Brazil Univ. of Sao Paulo Brazil NICHD CRS Sao Paulo, Brazil Puerto Rico San Juan City Hosp. PR NICHD CRS San Juan, Puerto Rico Less <<
NCT00160849 HIV Infections Phase 4 Completed - Brazil ... More >> Hospital Geral de Nova Iguaçu Nova Iguaçu, Rio de Janeiro, Brazil, 01620.020 Projeto Praça Onze Rio de Janeiro, Brazil, 20210.030 Less <<
NCT00571961 - Completed - -
NCT00084149 - Completed - -
NCT01165645 Hodgkin Lymphoma ... More >> Stage I Adult Hodgkin Lymphoma Stage II Adult Hodgkin Lymphoma Stage III Adult Hodgkin Lymphoma Stage IV Adult Hodgkin Lymphoma Less << Not Applicable Withdrawn(no patients enrolled... More >>) Less << - United States, Minnesota ... More >> Mayo Clinic Rochester, Minnesota, United States, 55905 Less <<
NCT00084149 HIV Infections Phase 2 Completed - United States, Minnesota ... More >> University of Minnesota, ACTU Minneapolis, Minnesota, United States, 55455-0392 United States, New York Beth Israel Med. Ctr., ACTU New York, New York, United States, 10003 NY Univ. HIV/AIDS CRS New York, New York, United States, 10016-6481 United States, Ohio MetroHealth CRS Cleveland, Ohio, United States, 44109-1998 Less <<
NCT00833378 Hepatitis C Phase 1 Completed - United States, New York ... More >> GSK Investigational Site Buffalo, New York, United States, 14202 Less <<
NCT01057433 Healthy Volunteers Phase 4 Completed - United States, Texas ... More >> Austin, Texas, United States Less <<
NCT01231451 HIV Infection Phase 1 Withdrawn(Ethics board said th... More >>e study could not be fully justified.) Less << June 2011 United Kingdom ... More >> St Stephen's Centre London, United Kingdom, SW10 9NH Less <<
NCT01057433 - Completed - -
NCT01045369 HIV Infections Phase 4 Completed - United States, Texas ... More >> Therapeutic Concepts, PA Houston, Texas, United States, 77004 Less <<
NCT00413153 HIV Infections Not Applicable Completed - United States, Massachusetts ... More >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Less <<
NCT00711009 Human Immunodeficiency Virus I... More >>nfection Less << Phase 3 Completed - -
NCT02159352 - Completed - -
NCT00711009 - Completed - -
NCT00865475 HIV Infection ... More >> HIV Infections Less << Phase 4 Completed - Spain ... More >> Hospital Ntra.Sra. de Zumarraga Zumarraga, Guipuzcua, Spain, 28700 Hospital Severo Ochoa Leganes, Madrid, Spain, 28911 Hospital de Donostia Donostia, San Sebastian, Spain, 20014 Hospital de Basurto Bilbao, Vizcaya, Spain, 48013 Hospital Doce de Octubre Madrid, Spain, 28041 Hospital La Paz Madrid, Spain, 28046 H. Son Dureta Mallorca, Spain Less <<
NCT02159352 Hepatitis C Phase 1 Completed - United States, Texas ... More >> Healthcare Discoveries, Llc D/B/A Icon Development Solutions San Antonio, Texas, United States, 78209 Less <<
NCT01772940 HIV-1 Infection Phase 4 Completed - Congo ... More >> Cliniques Universitaires de Lubumbashi Lubumbashi, Katanga, Congo Less <<
NCT00247143 HIV AIDS Not Applicable Unknown - United States, California ... More >> San Francisco VA Medical Center Recruiting San Francisco, California, United States, 94121 Principal Investigator: Harry W. Lampiris, M.D. Less <<
NCT00723775 Infection, Human Immunodeficie... More >>ncy Virus Less << Phase 1 Completed - United States, New York ... More >> GSK Investigational Site Buffalo, New York, United States, 14202 Less <<
NCT00413153 - Completed - -
NCT01533272 HIV Infection Phase 4 Completed - Spain ... More >> Hospital Clinic de Barcelona Barcelona, Spain, 08036 Less <<
NCT00752856 HIV Infections Phase 2 Completed - United States, California ... More >> Living Hope Clinical Foundation Long Beach, California, United States, 90813 University Southern California Los Angeles, California, United States, 90033 Univerisity California Irvine Orange, California, United States, 92868 Desert AIDS Project Palm Springs, California, United States, 92262 University California San Diego San Diego, California, United States, 92103 Harbor-UCLA Torrance, California, United States, 90502 Less <<
NCT00640263 HIV Infections Phase 3 Completed - Burkina Faso ... More >> Université de Ouagadougou Ouagadougou, Burkina Faso South Africa East London Hospital Complex East London, South Africa Uganda Dept of Paediatrics and Child Health, Makerere University Kampala, Uganda Zambia Dept of Paediatrics and Child Health, School of Medicine, University of Zambia Lusaka, Zambia Less <<
NCT00357552 HIV Infections Not Applicable Completed - India ... More >> Y.R.G Ctr, for AIDS Research and Education (11701) Chennai, India Malawi University of North Carolina Lilongwe CRS (12001) Lilongwe, Malawi South Africa Wits HIV CRS (11101) Johannesburg, Gauteng, South Africa Tanzania Kilimanjaro Christian Medical CRS Moshi, Tanzania Thailand Chiang Mai University ACTG CRS (11501) Chiang Mai, Thailand, 50202 Less <<
NCT00865007 HIV Infection ... More >> Lipodystrophy HIV Infections Less << Phase 4 Completed - Spain ... More >> Hospital Severo Ochoa Leganes, Madrid, Spain, 28911 Hospital Xeral Cies Vigo, Pontevedra, Spain, 36204 Hospital de Donostia Donostia, San Sebastian, Spain, 20014 Hospital de Basurto Bilbao, Vizcaya, Spain, 48013 Hospital General Universitario de Alicante Alicante, Spain, 03010 Hospital Sant Creu i Sant Pau Barcelona, Spain, 08025 Hospital Clinico y Provincial Barcelona, Spain, 08036 Hospital Universitario Reina Sofia Cordoba, Spain, 14004 Hospital La Paz Madrid, Spain, 28006 Hospital Doce de Octubre Madrid, Spain, 28041 Hospital La Paz Madrid, Spain, 28046 Less <<
NCT00103012 - Completed - -
NCT00357552 - Completed - -
NCT00420355 HIV Infection Phase 4 Terminated(Unexpected adverse ... More >>event) Less << - United States, Oklahoma ... More >> OUHSC General Clinical Research Center Oklahoma City, Oklahoma, United States, 73104 Less <<
NCT00281606 HIV Infection Phase 4 Completed - United States, California ... More >> UCI Irvine, California, United States, 92668 USC Los Angeles, California, United States, 90033 UCSD San Diego, California, United States, 92103 Santa Clara Valley Medical Center San Jose, California, United States, 95128 Harbor-UCLA Medical Center Torrance, California, United States, 90502 Less <<
NCT00103012 Healthy Phase 4 Completed - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT00654147 HIV Infections Phase 2 Completed - United States, Florida ... More >> University of Miami AIDS Clinical Research Unit Miami, Florida, United States, 33136 Less <<
NCT00654147 - Completed - -
NCT00358917 - Completed - -
NCT00775606 - Terminated(Study stopped 12/20... More >>10 due to poor enrollment. Only 15 of 60 needed enrolled.) Less << - -
NCT00234923 HIV Infection Phase 3 Completed - -
NCT00994344 HIV Infections Phase 4 Completed - Spain ... More >> Germans Trias i Pujol Hospital Badalona, Barcelona, Spain, 08916 Hospital Universitario de Canarias Santa Cruz de Tenerife, Canarias, Spain, 38320 Less <<
NCT00508222 HIV Infections Phase 3 Completed - Canada, British Columbia ... More >> University of British Columbia Vancouver, British Columbia, Canada, V6Z 2C7 Canada, Ontario The Ottawa Hospital, General Campus Ottawa, Ontario, Canada, K1H 8L6 Less <<
NCT00358917 Human Immunodeficiency Virus I... More >>nfections Less << Phase 3 Completed - United States, Illinois ... More >> Medical Information - Abbott (1-800-633-9110) Abbott Park, Illinois, United States, 60064 Less <<
NCT00946595 HIV Infections Phase 2 Phase 3 Completed - France ... More >> Service des maladies infectieuses et tropicales Hopital Saint-Antoine Paris, France, 72012 Less <<
NCT01068873 HIV Infections Phase 4 Terminated(Poor enrollment) - United States, Pennsylvania ... More >> Temple General Internal Medicine Philadelphia, Pennsylvania, United States, 19140 Less <<
NCT00775606 Acquired Immune Deficiency Syn... More >>drome Less << Phase 4 Terminated(Study stopped 12/20... More >>10 due to poor enrollment. Only 15 of 60 needed enrolled.) Less << - United States, Illinois ... More >> Rush University Medical Center Chicago, Illinois, United States, 60612 University of Illinois Medical Center Chicago, Illinois, United States, 60612 Howard Brown Health Center Chicago, Illinois, United States, 60613 University of Chicago Hospital Chicago, Illinois, United States, 60637 Less <<
NCT01031849 HIV Infections Phase 4 Terminated(patient sample not ... More >>reached) Less << - Spain ... More >> Fundación Jiménez Díaz Madrid, Spain, 28040 Hospital Clínico San Carlos Madrid, Spain, 28040 Less <<
NCT01255371 HIV Phase 3 Withdrawn(drug procurement iss... More >>ues) Less << December 2014 South Africa ... More >> Tshepang clinic, Limpopo University Pretoria, South Africa Tanzania NIMR-Mbeya Medical Research Program-Mbeya Referral Hospital Mbeya, Tanzania Less <<
NCT00102986 HIV Infections Not Applicable Completed - -
NCT00887120 HIV Infections Phase 2 Completed - Thailand ... More >> HIV-NAT, Thai Red Cross AIDS Research Center, Bangkok Bangkok, Thailand, 10330 Less <<
NCT00234975 HIV Infection Phase 4 Completed - Puerto Rico ... More >> Site Reference ID/Investigator# 4118 Bayamon, Puerto Rico, 00960 Site Reference ID/Investigator# 4119 Bayamon, Puerto Rico, 00961 Site Reference ID/Investigator# 6298 Juana Diaz, Puerto Rico, 00795 Site Reference ID/Investigator# 6284 Las Piedras, Puerto Rico, 00771 Site Reference ID/Investigator# 4101 Mayaguez, Puerto Rico, 00680 Site Reference ID/Investigator# 4116 Playa de Ponce, Puerto Rico, 00731 Site Reference ID/Investigator# 4117 Ponce, Puerto Rico, 00717-1563 Site Reference ID/Investigator# 4099 Ponce, Puerto Rico, 00731 Site Reference ID/Investigator# 4086 Rio Piedras, Puerto Rico, 00926 Site Reference ID/Investigator# 4080 San Juan, Puerto Rico, 00908 Site Reference ID/Investigator# 4100 Santurce, Puerto Rico, 00909 Less <<
NCT01662336 - Completed - -
NCT01307124 HIV-infected Children Phase 3 Completed - Thailand ... More >> Queen Sirikit National Institute of Child Health Bangkok, Thailand Prapokklao Hospital Chantaburi, Thailand Nakornping Hospital Chiang Mai, Thailand Srinagarind Hospital, Khon Kaen University Khon Kaen, Thailand Bamrasnaradura Institute Nonthaburi, Thailand, 11000 Phrachomklao Hospital Petchaburi, Thailand Buddhachinaraj Hospital Pitsanulok, Thailand Surin Hospital Surin, Thailand Sappasitthiprasong Hospital Ubonratchathani, Thailand Udonthani Hospital Udonthani, Thailand Less <<
NCT01095094 Brain Tumor A... More >>naplastic Astrocytoma Anaplastic Ependymoma Anaplastic Oligodendroglioma Brain Stem Glioma Giant Cell Glioblastoma Glioblastoma Gliosarcoma Mixed Glioma Less << Phase 2 Terminated(Study did not meet ... More >>its primary objective) Less << - United States, Ohio ... More >> Cleveland Clinic Taussig Institute, Case Comprehensive Cancer Center Cleveland, Ohio, United States, 44195 Less <<
NCT01095094 - Terminated(Study did not meet ... More >>its primary objective) Less << - -
NCT01662336 - Completed - -
NCT00648999 Human Immunodeficiency Virus Phase 4 Completed - Mexico ... More >> Site Ref # / Investigator 4049 Mexico City, Distrito Federal, Mexico, 01030 Site Ref # / Investigator 4050 Mexico City, Distrito Federal, Mexico, 01120 Site Ref # / Investigator 4051 Mexico City, Distrito Federal, Mexico, 09220 Site Ref # / Investigator 4077 Mexico City, Distrito Federal, Mexico, 10300 Site Ref # / Investigator 4056 Mexico City, Distrito Federal, Mexico Site Ref # / Investigator 4074 Leon, Guanajauto, Mexico Site Ref # / Investigator 4054 Morelia, Michoacan, Mexico Site Ref # / Investigator 4072 Tepic, Nayarit, Mexico Site Ref # / Investigator 4055 Culiacan, Sinaloa, Mexico Site Ref # / Investigator 4075 Merida, Yucatan, Mexico, 97219 Site Ref # / Investigator 4073 Chihuahua, Mexico, 31310 Site Ref # / Investigator 4052 Oaxaca, Mexico Site Ref # / Investigator 4053 Puebla, Mexico, 72570 Less <<
NCT01227590 Drug Interactions ... More >> Human Immunodeficiency Virus Less << Phase 1 Completed - United States, California ... More >> University of California, San Francisco San Francisco, California, United States, 94110 Less <<
NCT01328158 - Completed - Japan ... More >> Site Reference ID/Investigator# 57629 Fukuoka-shi, Japan Site Reference ID/Investigator# 57630 Hiroshima-shi, Japan Site Reference ID/Investigator# 57631 Hokkaido, Japan Site Reference ID/Investigator# 57628 Kitakyushu-shi, Japan Site Reference ID/Investigator# 57638 Kurashiki-shi, Japan Site Reference ID/Investigator# 57634 Kyoto, Japan Site Reference ID/Investigator# 57625 Nagoya-shi, Japan Site Reference ID/Investigator# 57626 Nagoya-shi, Japan Site Reference ID/Investigator# 57637 Niigata, Japan Site Reference ID/Investigator# 57632 Nishinomiya-shi, Japan Site Reference ID/Investigator# 57639 Osaka-shi, Japan Site Reference ID/Investigator# 57640 Osaka, Japan Site Reference ID/Investigator# 57636 Sendai-shi, Japan Site Reference ID/Investigator# 48722 Tokyo, Japan Site Reference ID/Investigator# 57641 Tokyo, Japan Site Reference ID/Investigator# 57643 Tokyo, Japan Site Reference ID/Investigator# 57644 Tokyo, Japan Site Reference ID/Investigator# 57645 Tokyo, Japan Site Reference ID/Investigator# 57646 Tokyo, Japan Site Reference ID/Investigator# 57647 Tokyo, Japan Site Reference ID/Investigator# 57648 Tokyo, Japan Site Reference ID/Investigator# 57650 Tokyo, Japan Site Reference ID/Investigator# 57633 Yokohama-shi, Japan Less <<
NCT02671383 HIV Infections Phase 3 Completed - South Africa ... More >> Charlotte Maxeke Johannesburg Academic Hospital Johannesburg, Gauteng, South Africa, 2196 Less <<
NCT01328158 - Completed - -
NCT00679926 HIV Infections Phase 4 Terminated(Lack of enrollment) - United States, Oklahoma ... More >> OSU Internal Medicine Specialty Clinic Tulsa, Oklahoma, United States, 74127 Less <<
NCT01049685 HIV Infections Phase 4 Unknown March 2010 Brazil ... More >> SAE e Hospital Dia Domingos Alves Meira Botucatu, SP, Brazil, 18603-790 Less <<
NCT00766818 Pregnancy HIV Phase 1 Completed - United States, North Carolina ... More >> University of North Carolina Chapel Hill, North Carolina, United States, 27599 Less <<
NCT01189695 HIV AIDS ... More >> Lopinavir Treatment Failure Less << Phase 4 Completed - Thailand ... More >> Bamrasnaradura Infectious Diseases Institute Nonthaburi, Thailand, 11000 Less <<
NCT00564772 Healthy Phase 4 Completed - United States, Minnesota ... More >> Prism Research Inc St Paul, Minnesota, United States, 55114 Less <<
NCT00632970 HIV Infections Phase 4 Terminated(no patients complet... More >>ed) Less << - United States, District of Col... More >>umbia George Washington University Medical Faculty Associates Washington, District of Columbia, United States, 20037 Less <<
NCT00743470 HIV Tuberculo... More >>sis Less << Phase 1 Terminated - United States, Illinois ... More >> Site Reference ID/Investigator# 11441 Waukegan, Illinois, United States, 60085 Less <<
NCT00159224 HIV Infections Phase 4 Completed - Argentina ... More >> Helios Salud Buenos Aires,, Argentina, 1141 Fundacion Huesped Buenos Aires, Argentina, C1202ABB Canada, British Columbia University of British Columbia Vancouver, British Columbia, Canada Mexico Instituto Nacional de Ciencias Medicas y Nutrición "Salvador Zubirán Mexico DF, Mexico Less <<
NCT00632970 - Terminated(no patients complet... More >>ed) Less << - -
NCT00438152 HIV Infections Phase 4 Completed - United Kingdom ... More >> Royal Free Hampstead NHS Trust London, United Kingdom, NW32QG Less <<
NCT00344487 - Terminated(Inability to enroll... More >> subjects.) Less << - -
NCT00802334 HIV Phase 2 Completed - Thailand ... More >> HIV-NAT Bangkok, Thailand, 10330 Less <<
NCT00866021 HIV/HCV Co-infection ... More >> HIV Infections Less << Phase 4 Completed - Spain ... More >> Hospital Germans Trias i Pujol Badalona, Barcelona, Spain, 08910 Hospital Donostia San Sebastian, Guipuzcoa, Spain Hospital General Sta. Mª del Rosell Cartagena, Murcia, Spain, 30203 Hospital General de Castellón Castellón, Spain, 12004 Hospital Gregorio Marañón Madrid, Spain, 28007 Hospital Ramón y Cajal Madrid, Spain, 28034 Hospital la Paz Madrid, Spain, 28046 Hospital La Princesa Madrid, Spain Hospital La Fe Valencia, Spain, 46009 Hospital General Universitario de Valencia Valencia, Spain, 46014 Less <<
NCT00474201 - Completed - -
NCT01088516 HIV Phase 4 Completed - Zambia ... More >> Chelstone Clinic Lusaka, Zambia Less <<
NCT00344487 HIV Not Applicable Terminated(Inability to enroll... More >> subjects.) Less << - United States, Maryland ... More >> University of Maryland, Institute of Human Virology Baltimore, Maryland, United States, 21201 Less <<
NCT00474201 Healthy Volunteers Not Applicable Completed - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT01159275 HIV-1 Infections Phase 1 Phase 2 Completed - Thailand ... More >> HIV-NAT, Thai Red Cross AIDS Research Centre Bangkok, Thailand, 10330 Less <<
NCT00619944 HIV Infections Phase 4 Completed - Uganda ... More >> Infectious Diseases Institute, Faculty of Medicine, Makerere University Kampala, Uganda, 22418 Less <<
NCT00665951 HIV Infections Phase 1 Completed - Netherlands ... More >> Radboud University Medical Centre Nijmegen, Gelderland, Netherlands Less <<
NCT00762320 - Completed - -
NCT02845843 Middle East Respiratory Syndro... More >>me Coronavirus (MERS-CoV) Less << Phase 2 Phase 3 Unknown July 2018 Saudi Arabia ... More >> Intensive Care Unit, King Abdulaziz Medical City, National Guard Health Affairs Recruiting Riyadh, Saudi Arabia, 11426 Contact: Yaseen M Arabi, MD    +966(11)8011111 ext 18855    yaseenarabi@yahoo.com    Principal Investigator: Yaseen M Arabi, MD          King Abdullah International Medical Research Center Not yet recruiting Riyadh, Saudi Arabia, 22490 Contact: Yaseen Arabi, MD, FCCP, FCCM    966-11-8011111 ext 18899    arabi@ngha.med.sa Less <<
NCT01196195 Antiretroviral Therapy in HIV-... More >>1 Infected Children Less << Phase 2 Phase 3 Completed - Germany ... More >> Charite University Hospital Berlin Berlin, Germany Department of Pediatric Oncology Hematology and Immunology KA02 Dusseldorf, Germany J W Goethe University Frankfurt, Germany Immundefekt-Ambulanz, Dr. von Haunersches Kinderspital Munich, Germany Ireland Our Lady's Children's Hospital Dublin, Ireland Netherlands Emma Childrens Hospital Amsterdam, Netherlands UMC St. Radboud Nijmegen, Netherlands Thailand Program for HIV Prevention and Treatment (PHPT)/IRD 174 Changklan, Muang, Chiang Mai, Thailand, 50100 HIV-NAT Thai Red Cross AIDS Research Centre Bangkok, Thailand United Kingdom Birmingham Heartlands Hospital Birmingham, United Kingdom University Hospital Bristol Bristol, United Kingdom Evelina Children's Hospital London, United Kingdom Great Ormond Street Hospital London, United Kingdom King's College Hospital London, United Kingdom St. Mary's Hospital London, United Kingdom Nottingham City Hospital Campus Nottingham, United Kingdom John Radcliffe Hospital Oxford, United Kingdom Less <<
NCT01083810 - Completed - -
NCT00762320 HIV Infections Not Applicable Completed - United States, Arizona ... More >> Phoenix Children's Hospital Phoenix, Arizona, United States, 85016 Less <<
NCT00981318 HIV Infections ... More >> Acquired Immunodeficiency Syndrome Less << Phase 4 Terminated(unable to enroll ex... More >>pected number of subjects) Less << - United States, Florida ... More >> Barry M. Rodwick, M. D. Safety Harbor, Florida, United States, 34695 Less <<
NCT00752037 HIV Infections Phase 4 Completed - United States, New Jersey ... More >> Saint Michael's Medical Center Newark, New Jersey, United States, 07102 Less <<
NCT01237444 HIV Infection Phase 3 Completed - Argentina ... More >> Fundacion Huesped Ciudad de Buenos Aires, Argentina, C1202ABB Less <<
NCT00621166 HIV Infections Phase 2 Completed - Thailand ... More >> Department of Obsterics and Gynecology, Faculty of Medicine, Chulalongkorn University Bangkok, Thailand, 10330 Less <<
NCT01083810 - Completed - -
NCT00605098 HIV Infections ... More >> Pregnancy Less << Phase 4 Completed - Brazil ... More >> Hospital Geral de Nova Iguaçu (HGNI) Nova Iguaçu, Rio de Janeiro, Brazil, 26030-380 Instituto de Pesquisa Clínica Evandro Chagas Rio de Janeiro, RJ, Brazil, 21040-900 Hospital dos Servidores do Estado Rio de Janeiro, Brazil, 20221903 Less <<
NCT01076985 - Completed - Japan ... More >> Site Reference ID/Investigator# 35862 Aichi, Japan Site Reference ID/Investigator# 35863 Okayama, Japan Site Reference ID/Investigator# 35864 Osaka, Japan Site Reference ID/Investigator# 35865 Tokyo, Japan Site Reference ID/Investigator# 5326 Tokyo, Japan Less <<
NCT01076972 - Completed - -
NCT01076972 - Completed - Japan ... More >> Site Reference ID/Investigator# 36516 Aichi, Japan Site Reference ID/Investigator# 36517 Aichi, Japan Site Reference ID/Investigator# 36518 Chiba, Japan Site Reference ID/Investigator# 36519 Fukuoka, Japan Site Reference ID/Investigator# 36521 Fukuoka, Japan Site Reference ID/Investigator# 36522 Hiroshima, Japan Site Reference ID/Investigator# 36523 Hokkaido, Japan Site Reference ID/Investigator# 36524 Hyogo, Japan Site Reference ID/Investigator# 36525 Kanagawa, Japan Site Reference ID/Investigator# 36526 Kyoto, Japan Site Reference ID/Investigator# 36622 Miyagi, Japan Site Reference ID/Investigator# 36623 Miyagi, Japan Site Reference ID/Investigator# 36624 Niigata, Japan Site Reference ID/Investigator# 36625 Okayama, Japan Site Reference ID/Investigator# 36626 Osaka, Japan Site Reference ID/Investigator# 36627 Osaka, Japan Site Reference ID/Investigator# 36628 Shizuoka, Japan Site Reference ID/Investigator# 36629 Tokyo, Japan Site Reference ID/Investigator# 36630 Tokyo, Japan Site Reference ID/Investigator# 36631 Tokyo, Japan Site Reference ID/Investigator# 36632 Tokyo, Japan Site Reference ID/Investigator# 36633 Tokyo, Japan Site Reference ID/Investigator# 36634 Tokyo, Japan Site Reference ID/Investigator# 36635 Tokyo, Japan Site Reference ID/Investigator# 36636 Tokyo, Japan Site Reference ID/Investigator# 36637 Tokyo, Japan Site Reference ID/Investigator# 36638 Tokyo, Japan Site Reference ID/Investigator# 36639 Tokyo, Japan Site Reference ID/Investigator# 5342 Tokyo, Japan Less <<
NCT01139905 HIV-1 Infections Phase 2 Completed - Thailand ... More >> HIV-NAT Bangkok, Thailand, 10330 Less <<
NCT01660477 Pharmacokinetics of Isavuconaz... More >>ole Pharmacokinetics of Lopinavir/Ritonavir Healthy Volunteers Less << Phase 1 Completed - United States, California ... More >> Parexel International Glendale, California, United States, 91206 Less <<
NCT01076985 - Completed - -
NCT01172535 HIV Phase 2 Phase 3 Completed - United States, California ... More >> University of California, UC San Diego CRS La Jolla,, California, United States, 92093-0672 United States, Colorado Univ. of Colorado Denver NICHD CRS Aurora, Colorado, United States, 80045 United States, Massachusetts Boston Medical Center Ped. HIV Program NICHD CRS Boston, Massachusetts, United States, 02118 Brazil SOM Federal University Minas Gerais Brazil NICHD CRS Belo Horizonte, Minas Gerais, Brazil, 30130-100 Hosp. Santa Casa Porto Alegre Brazil NICHD CRS Porto Alegre, Rio Grande do Sul, Brazil, 90020-090 Hospital Federal dos Servidores do Estado NICHD CRS Rio de Janeiro, Brazil, 20221-903 Instituto de Puericultura e Pediatria Martagao Gesteira - UFRJ NICHD CRS Rio de Janeiro, Brazil, 21941-612 Hosp. Geral De Nova Igaucu Brazil NICHD CRS Rio de Janeiro, Brazil, 26030 Inst de Infectologia Emilio Ribas Sao Paulo Brazil NICHD CRS Sao Paulo, Brazil, 01246-900 Univ. of Sao Paulo Brazil NICHD CRS Sao Paulo, Brazil, 14049-900 South Africa Shandukani CRS Johannesburg, Gauteng, South Africa, 2001 Family Clinical Research Unit (FAM-CRU) CRS Tygerberg, Western Cape Province, South Africa, 7505 Thailand Siriraj Hospital Mahidol University CRS Bangkok, Bangkoknoi, Thailand, 10700 Bhumibol Adulyadej Hosp. CRS Saimai, Bangkok, Thailand, 10220 Prapokklao Hosp. CRS Chantaburi, Thailand, 22000 Chiang Mai University HIV Treatment (CMU HIV Treatment) CRS Chiang Mai, Thailand, 50200 Chiangrai Prachanukroh Hospital CRS Chiangrai, Thailand, 57000 Chonburi Hosp. CRS Chonburi, Thailand, 2000 Phayao Provincial Hosp. CRS Phayao, Thailand, 56000 Less <<
NCT00985543 - Completed - -
NCT01002898 HIV Phase 3 Completed - Thailand ... More >> Bamrasnaradura Infectious Diseases Institute Nonthaburi, Thailand, 11000 Less <<
NCT00810108 HIV/AIDS Treatment ... More >> HIV Infections Less << Phase 4 Completed - United States, California ... More >> University of California, San Diego - Skaggs School of Pharmacy and School of Medicine San Diego, California, United States, 92103 United States, District of Columbia Children's National Medical Center Washington, District of Columbia, United States, 20010 Less <<
NCT00771498 HIV Infection|Tuberculosis PHASE4 COMPLETED 2025-12-12 University of Espirito Santo, ... More >>Vitoria, ES, Brazil|Instituto de Pesquisa Clinica Evandro Chagas (IPEC), Rio de Janeiro, RJ, Brazil|Instituto Oswaldo Cruz (IOC), Rio de Janeiro, RJ, Brazil Less <<
NCT01581853 HIV Phase 4 Completed - Spain ... More >> Hospital del Mar Bercelona, Barcelona, Spain, 08003 Hospital Universitary de Bellvitge Hospitalet de Llobregat, Barcelona, Spain, 08907 Less <<
NCT00985543 Acquired Immunodeficiency Synd... More >>rome Less << Phase 1 Completed - United Kingdom ... More >> St Stephen's Centre, Chelsea and Westminster Hospital London, United Kingdom, SW10 9TH Less <<
NCT01074931 - Completed - China ... More >> Site Reference ID/Investigator# 7244 Guangdong, China, 510060 Site Reference ID/Investigator# 27865 Kunming, China, 650118 Site Reference ID/Investigator# 27864 Shanghai, China, 201508 Site Reference ID/Investigator# 27863 Shenzhen, China, 518020 Site Reference ID/Investigator# 27866 Zhengzhou, China, 450061 Less <<
NCT01172535 - Completed - -
NCT01700790 AIDS Tubercul... More >>osis Less << Phase 4 Active, not recruiting May 2019 Brazil ... More >> Instituto Nacional de Infectologia Evandro Chagas - Fiocruz(INI), Laboratorio de Pesquisa Clinica em Micobacterioses(LAPCLINTB) Rio de Janeiro, RJ, Brazil, 21040-900 Less <<
NCT02348177 Acquired Immunodeficiency Synd... More >>rome Tuberculosis Less << Phase 4 Completed - South Africa ... More >> The Children's Infectious Disease Clinical Research Unit; University of Stellenbosch Cape Town, Western Cape, South Africa, 7505 Enhancing Care Foundation; Wendworth Hospital Durban, South Africa, 4013 Perinatal HIV Research Unit Johannesburg, South Africa, 1864 Shandukani Research WRHI Johannesburg, South Africa, 2001 Empilweni Services and Research Unit Johannesburg, South Africa, 2093 Less <<
NCT00810108 - Completed - -
NCT01074931 - Completed - -
NCT01935830 Healthy Volunteers Early Phase 1 Completed - United States, Missouri ... More >> Washington University School of Medicine Saint Louis, Missouri, United States, 63110 Less <<
NCT00110877 HIV Infection Phase 3 Completed - -
NCT00608569 - Completed - -
NCT02431975 HIV Phase 4 Recruiting July 31, 2020 South Africa ... More >> Rahima Moosa Mother and Child Hospital Recruiting Johannesburg, Gauteng, South Africa Contact: Ashraf Coovadia, MBChB    +27 114709290    Ashraf.Coovadia@wits.ac.za    Contact: Karl Technau, MBChB       karltechnau@gmail.com Less <<
NCT00258557 HIV Phase 3 Completed - -
NCT00608569 HIV Infections Not Applicable Completed - Botswana ... More >> Gaborone Prevention/Treatment Trials CRS Gaborone, Botswana Brazil Instituto de Pesquisa Clinica Evandro Chagas (12101) Rio de Janeiro, Brazil, 21045 Haiti Les Centres GHESKIO CRS Bicentenaire, Port-au-Prince, Haiti, HT-6110 Peru San Miguel CRS San Miguel, Lima, Peru Barranco CRS Lima, Peru, 18 South Africa Wits HIV CRS Johannesburg, Gauteng, South Africa Uganda JCRC CRS Kampala, Uganda Zambia Kalingalinga Clinic CRS Lusaka, Zambia Zimbabwe UZ-Parirenyatwa CRS Harare, Zimbabwe Less <<
NCT00102960 HIV Infections Phase 3 Completed - -
NCT00666055 - Completed - United States, North Carolina ... More >> The University of North Carolina at Chapel Hill Chapel Hill, North Carolina, United States, 27599-7215 Less <<
NCT02231281 Acute HIV Infection Phase 3 Active, not recruiting December 2018 China, Beijing ... More >> Beijing You'an Hospital, Capital Medical University Beijing, Beijing, China National Center for STD and AIDS Control and Prevention, Chinese Center for Disease Control and Prevention Beijing, Beijing, China China, Guangxi The First Affiliated Hospital of Guangxi Medical University Nanning, Guangxi, China China, Liaoning China Medical University Shenyang, Liaoning, China China, Shaanxi Department of Infectious Diseases, Tangdu Hospital, The Fourth Military Medical Universit Xi'an, Shaanxi, China, 710038 China, Shandong Shandong Center for Disease Control and Prevention Jinan, Shandong, China China, Zhejiang Zhejiang University Hangzhou, Zhejiang, China Less <<
NCT00102960 - Completed - -
NCT02397096 HIV-1 Infection Phase 3 Active, not recruiting November 2, 2021 -
NCT00036452 HIV Infections Phase 2 Completed - -
NCT01213316 - Completed - -
NCT00041964 - Completed - -
NCT00197145 Infection, Human Immunodeficie... More >>ncy Virus I Less << Phase 3 Terminated - -
NCT00539201 Healthy Subjects Phase 1 Terminated - United States, Wisconsin ... More >> GSK Investigational Site Madison, Wisconsin, United States, 53704 Less <<
NCT00197145 - Terminated - -
NCT02011958 Visceral Leishmaniasis Phase 3 Unknown April 2017 Ethiopia ... More >> MSF Abdurafi, Ethiopia Leishmaniasis Research Center, University Hospital of Gondar Gondar, Ethiopia Less <<
NCT00031044 HIV Infections Phase 1 Phase 2 Completed - United States, Colorado ... More >> Univ of Colorado Health Sciences Ctr Denver, Colorado, United States, 80262 United States, Florida Miami University Miami, Florida, United States United States, Massachusetts Harvard (Massachusetts General Hosp) Boston, Massachusetts, United States, 02114 Brigham and Womens Hosp Boston, Massachusetts, United States, 02118 United States, New York Cornell Univ Med Ctr New York, New York, United States, 10021 Columbia Presbyterian Med Ctr New York, New York, United States, 10032 United States, Ohio Case Western Reserve Univ Cleveland, Ohio, United States, 44106 MetroHealth Med Ctr Cleveland, Ohio, United States, 441091998 Puerto Rico Univ of Puerto Rico San Juan, Puerto Rico, 00936-5067 Less <<
NCT00846599 - Completed - United States, Massachusetts ... More >> Tufts University Boston, Massachusetts, United States, 02111 Less <<
NCT00850395 - Completed - -
NCT00055120 HIV Infections ... More >> AIDS-Related Opportunistic Infections Less << Phase 4 Completed - -
NCT00850395 - Completed - -
NCT02616783 HIV-1 Infection Phase 3 Completed - Belgium ... More >> CHU Saint-Pierre University Hospital Brussels, Belgium University Hospital Gent Ghent, Belgium France CHU - Groupe Saint-Andre Bordeaux, France CHU de Dijon Dijon, France Hopital Europeen Marseille Marseille, France C.H.U. de Nantes Nantes, France C.H.U. de NICE Nice, France Hopital Saint Louis Paris cedex 10, France Hopital Saint Antoine Paris cedex 12, France CHU Hotel Dieu Paris, France Hopital Necker les Enfants Malades Paris, France Hopital Haut-Leveque Pessac, Cedex, France Service des Maladies Infectieuses et du Voyageur Tourcoing, France Italy Azienda Ospedaliera Papa Giovanni XXIII Bergamo, Italy Busto Arsizio Hospital Busto Arsizio, Italy IRCCS A.O.U. San Martino Genova, Italy Azienda Ospedaliera Luigi Sacco Milano, Italy Azienda Ospedaliero Universitaria Policlinico di Modena Modena, Italy U.O. Malattie Infettive Pescara, Italy Istituto Nazionale Malattie Infettive Lazzaro Spallanzani I.R.C.C.S. Roma, Italy Azienda Ospedaliero Universitaria di Sassari Sassari, Italy Dipartimento di Malattie Infettive e Tropicali Torino, Italy Spain Hospital Clinic de Barcelona Barcelona, Spain Hospital de la Santa Creu i Sant Pau Barcelona, Spain Hospital Universitari Germans Trias i Pujol Barcelona, Spain Hospital Vall d'Hebron Barcelona, Spain Hospital 12 de Octubre Madrid, Spain Hospital General Universitario Gregorio Maranon Madrid, Spain Hospital Universitario La Paz Madrid, Spain Ramon Y Cajal University Hospital Madrid, Spain Hospital Costa Del Sol Marbella, Spain Hospital General Universitario de Valencia Valencia, Spain United Kingdom Royal Victoria Hospital Belfast, United Kingdom Mortimer Market Centre London, United Kingdom Newcastle Royal Victoria Infirmary Newcastle Upon Tyne, United Kingdom Less <<
NCT02469246 HIV-1 Infection Phase 3 Active, not recruiting March 2019 -
NCT02121795 - Active, not recruiting - -
NCT02469246 - Active, not recruiting - -
NCT00259727 - Completed - United States, California ... More >> VA Medical Center, San Francisco San Francisco, California, United States, 94121 Less <<
NCT00050908 - Completed - United States, California ... More >> UCLA School of Med Los Angeles, California, United States, 90095-1793 Univ of California, San Diego Antiviral Research Ctr San Diego, California, United States, 92103 United States, Hawaii Univ of Hawaii Honolulu, Hawaii, United States, 96816-2396 United States, Illinois Northwestern Univ Chicago, Illinois, United States, 46202 United States, Indiana Indiana Univ Hosp Indianapolis, Indiana, United States, 46202-5250 Methodist Hosp of Indiana Indianapolis, Indiana, United States, 46202-5250 Wishard Hosp Indianapolis, Indiana, United States, 46202 United States, New York Chelsea Clinic New York, New York, United States, 10011 United States, Ohio Univ of Cincinnati Cincinnati, Ohio, United States, 43210-1282 Less <<
NCT01252940 HIV-1 Infection Phase 3 Completed - -
NCT01252940 - Completed - -
NCT01475838 Acquired Immunodeficiency Synd... More >>rome HIV Infections Less << Phase 3 Completed - -
NCT02121795 HIV-1 Infection Phase 3 Active, not recruiting January 2019 -
NCT01231685 HIV Hepatitis... More >> C Liver Fibrosis Less << Phase 2 Completed - Canada, British Columbia ... More >> Providence Health Care- St. Paul's Hospital Vancouver, British Columbia, Canada, V6Z 1Y6 Canada, Ontario University Health Network - Toronto General Hospital Division Toronto, Ontario, Canada, M5G2N2 Canada, Quebec Montreal Chest Institute Montreal, Quebec, Canada Less <<
NCT02605954 HIV-1 Infection Phase 3 Completed - -
NCT02302547 HIV Phase 3 Completed - France ... More >> Unité des Maladies Infectieuses, CHU de CAEN Caen, France, 14033 Service des Maladies Infectieuses, CHR Orléans La Source, ORLEANS CEDEX 2 CHR d'ORLEANS, France, 45067 Service d'Immunologie Clinique centre de Vaccination anti- VIH ANRS Hopital Henri- Mondor Creteil, France, 94010 Service de Médecine Interne et Maladies Infectieuses, Groupe Hospitalier La Rochelle, Cedex 01 La Rochelle, France, 17019 Service de Pneumologie, centre Hospitalier Fontenoy, CH de CHARTRES Le Coudray, France, 28630 CHU de NANCY Nancy, France, 54035 Service des maladies Infectieuses et tropicales, CH GEORGES RENON Niort, France, 79021 Service des Maladies Infectieuses et tropicales, APHP SAINT LOUIS Paris, France, 75475 Hospital Tenon Paris, France, 75970 Centre de diagnostic et thérapeutique, Hopital Hotel Dieu Paris, France, 94010 Consultation Maladies Infectieuses, Chu de Poitiers, Cedex Poitiers, France, 86021 Maladies Infectieuses, CHU de ROUEN Rouen, France, 76031 Service de Médecine Interne, CH de SAINTONGE- BP 326 Saintes, France, 17108 Médecine Interne, Hôpital FOCH Suresnes, France, 92151 Service Universitaire des Maladies Infectieuses et du Voyageur, CH DRON Tourcoing, France, 59200 Service de Medecine Interne et Maladies Infectieuses, CHRU BRETONNEAU, TOURS CEDEX9 Tours, France, 37044 Less <<
NCT02605954 - Completed - -
NCT01213316 - Completed - -
NCT01061151 HIV Infections Phase 3 Completed - India ... More >> Byramjee Jeejeebhoy Medical College (BJMC) CRS Pune, Maharashtra, India, 411001 Malawi Blantyre CRS Blantyre, Malawi Malawi CRS Lilongwe, Malawi South Africa Soweto IMPAACT CRS Johannesburg, Gauteng, South Africa, 1862 Shandukani Research CRS Johannesburg, Gauteng, South Africa, 2001 Durban Paediatric HIV CRS Durban, KwaZulu-Natal, South Africa, 4001 Umlazi CRS Durban, KwaZulu-Natal, South Africa, 4001 Family Clinical Research Unit (FAM-CRU) CRS Cape Town, Western Cape, South Africa, 7505 Tanzania Kilimanjaro Christian Medical Centre (KCMC) Moshi, Tanzania Uganda MU-JHU Research Collaboration (MUJHU CARE LTD) CRS Kampala, Uganda Zambia George CRS Lusaka, Zambia Zimbabwe Seke North CRS Chitungwiza, Zimbabwe St Mary's CRS Chitungwiza, Zimbabwe Harare Family Care CRS Harare, Zimbabwe Less <<
NCT01637233 - Completed - Argentina ... More >> Hospital Ramos Mejía Buenos Aires, Argentina, C1221ADC Fundación IDEAA Buenos Aires, Argentina, C1405CKC CAICI Rosario, Argentina Thailand Chulalongkorn University Hospital Bangkok, Thailand, 10330 United Kingdom Brighton & Sussex University NHS Trust Brighton, Sussex, United Kingdom, BN21ES, Imperial Healthcare, St. Mary's Hospital London, United Kingdom, W2 Less <<
NCT00080522 HIV Infections Not Applicable Completed - South Africa ... More >> University of the Witwatersrand/Clinical HIV Research Unit Johannesburg, Gauteng, South Africa, 2013 University of Cape Town/Masiphumelele Cape Town, South Peninsula, South Africa, 8005 Less <<
NCT01475838 - Completed - -
NCT00102206 HIV Infections Phase 2 Completed - United States, Illinois ... More >> Chicago Children's CRS Chicago, Illinois, United States, 60614 United States, New York Columbia IMPAACT CRS New York, New York, United States SUNY Stony Brook NICHD CRS Stony Brook, New York, United States, 11794-8111 United States, North Carolina DUMC Ped. CRS Durham, North Carolina, United States, 27710 Less <<
NCT01061151 - Completed - -
NCT02157311 HIV-1 Infection Phase 3 Completed - France ... More >> Hôpital Meynard Fort-de-france, Martinique, France, 97261 Hôpital Avicenne Bobigny, France, 93000 CHU Côte de Nacre Caen, France, 14033 Centre Hospitalier Sud Francilien Corbeil Essonnes, France, 91100 Hôpital Le Bocage Dijon, France, 21079 Hôpital Raymond Poincaré Garches, France, 92380 Hôpital Bicêtre Kremlin Bicetre, France, 94275 Hôpital Gui de Chauliac Montpellier, France, 34295 Hôpital Saint-Antoine Paris, France, 75012 Hôpital Pitié-Salpêtrière Paris, France, 75013 Hôpital Européen Georges Pompidou Paris, France, 75015 Hôpital Necker Paris, France, 75015 Hôpital Bichat Paris, France, 75018 Hôpital Tenon Paris, France, 75020 Hôpital Foch Suresnes, France, 92151 Hôpital Purpan Toulouse, France, 31059 Hôpital Bretonneau Tours, France, 37044 Less <<
NCT00039741 HIV Infections Phase 2 Phase 3 Completed - -
NCT03631732 HIV-1 Infection Phase 3 Recruiting August 2020 -
NCT01814722 - Terminated(The trial was termi... More >>nated early due to slow recruitment.) Less << - -
NCT00039741 - Completed - -
NCT01814722 - Terminated(The trial was termi... More >>nated early due to slow recruitment.) Less << - -
NCT00427297 HIV Infections Phase 3 Terminated(There is no longer ... More >>equipoise. DSMB recommended termination.) Less << - Kenya ... More >> Kenyatta National Hospital, University of Nairobi Nairobi, Kenya Less <<
NCT01637259 Proteinuria H... More >>IV Less << Phase 4 Completed - Argentina ... More >> Hospital Italiano de Buenos Aires Buenos Aires, Ciudad de Buenos Aires, Argentina, C1181ACH Hospital General de Agudos J M Ramos Mejia Buenos Aires, Ciudad de Buenos Aires, Argentina, C1221ADC Fundación IDEAA Buenos Aires, Ciudad de Buenos Aires, Argentina, C1405CKC Australia, New South Wales St. Vincent's Hospital Sydney, New South Wales, Australia, 2010 Australia, Queensland Brisbane Sexual Health and HIV Service Brisbane, Queensland, Australia, 4000 Canada, Alberta Southern Alberta Clinic Calgary, Alberta, Canada, T2R OX7 Canada, Ontario University Health Network - Toronto General Hospital Toronto, Ontario, Canada, M5G 2N2 Canada, Quebec Clinic Opus/Lori Montreal, Quebec, Canada, H3A 1T1 Germany Klinikum der Universitat Zu Koln Cologne, Germany, 50937 Universitätsklinikum Düsseldorf, Klinik für Gastroenterologie, Hepatologie und Infektiologie, MX-Ambulanz Dusseldorf, Germany, 40225 Japan Nagoya Medical Center Nagoya, Japan, 460-0001 Mexico Instituto Nacional de Ciencias Medicas y Nutriciòn Salvador Zubiran Mexico City, Tlalpan DF, Mexico, 14000 Thailand Chulalongkorn University Hospital Bangkok, Thailand, 10330 United Kingdom Western General Hospital Edinburgh, Lothian, United Kingdom Brighton & Sussex University NHS Trust Brighton, Sussex, United Kingdom Less <<
NCT00966329 HIV HIV Infec... More >>tions Less << Phase 4 Completed - Spain ... More >> Germans Trias i Pujol Hospital Badalona, Barcelona, Spain, 08916 Lluita contra la Sida Foundation, HIV Unit, Irsi Caixa Foundation Badalona, Barcelona, Spain, 08916 Lluita contra la Sida Foundation, HIV Unit Badalona, Barcelona, Spain, 08916 Less <<
NCT01174914 HIV Seropositivity Phase 2 Completed - Mali ... More >> University Hospital of Point G Bamako, Mali, BP0 Box 333 Less <<
NCT00100581 HIV Infections ... More >> Hepatitis C Less << Not Applicable Completed - United States, New York ... More >> Columbia Univ., HIV Prevention and Treatment Medical Ctr. New York, New York, United States, 10032-3784 United States, Texas Univ. of Texas Southwestern Med. Ctr., Amelia Court Continuity Clinic Dallas, Texas, United States, 75235-9173 Less <<
NCT00255840 - Completed - -
NCT00255840 HIV Infections Not Applicable Completed - -
NCT02285114 HIV-1 Phase 2 Phase 3 Recruiting December 2024 United States, California ... More >> UCLA Recruiting Los Angeles, California, United States, 90095 United States, Colorado Children's Hospital Colorado Recruiting Aurora, Colorado, United States United States, Pennsylvania St. Christopher's Hospital, for Children Recruiting Philadelphia, Pennsylvania, United States, 19134 United States, Tennessee St. Judes Children's Research Hospital Recruiting Memphis, Tennessee, United States, 38105 United States, Washington Seattle Children's Hospital Recruiting Seattle, Washington, United States Panama Hospital del Nino Recruiting Panama City, Panama South Africa Be Part Yoluntu Centre Recruiting Cape Town, South Africa University of Stellenbosch Recruiting Cape Town, South Africa Rahima Moosa Mother and Child Hopsital Recruiting Johannesburg, South Africa Less <<
NCT00148785 HIV Infections Phase 4 Completed - United States, Georgia ... More >> Grady Infectious Diseases Program Atlanta, Georgia, United States, 30308 Less <<
NCT00014937 HIV Infections Not Applicable Completed - -
NCT00427297 - Terminated(There is no longer ... More >>equipoise. DSMB recommended termination.) Less << - -
NCT02614027 - Completed - Spain ... More >> Ramon y Cajal Hospital Madrid, Spain, 28034 Less <<
NCT00665847 - Completed - -
NCT00027339 HIV Infections Phase 2 Completed - United States, California ... More >> USC CRS Los Angeles, California, United States Stanford CRS Palo Alto, California, United States, 94305-5107 UC Davis Medical Center Sacramento, California, United States, 95814 Ucsd, Avrc Crs San Diego, California, United States, 92103 United States, Colorado University of Colorado Hospital CRS Aurora, Colorado, United States, 80262 United States, Florida Univ. of Miami AIDS CRS Miami, Florida, United States United States, Indiana Indiana Univ. School of Medicine, Wishard Memorial Indianapolis, Indiana, United States, 46202 Methodist Hosp. of Indiana Indianapolis, Indiana, United States, 46202 United States, New York Beth Israel Med. Ctr., ACTU New York, New York, United States, 10003 NY Univ. HIV/AIDS CRS New York, New York, United States, 10016 United States, North Carolina Unc Aids Crs Chapel Hill, North Carolina, United States, 275997215 Duke Univ. Med. Ctr. Adult CRS Durham, North Carolina, United States, 27710 United States, Tennessee Vanderbilt Therapeutics CRS Nashville, Tennessee, United States, 37203 Puerto Rico Puerto Rico-AIDS CRS San Juan, Puerto Rico, 00936-5067 Less <<
NCT01585753 - Completed - Argentina ... More >> Hospital General de Agudos "Dr. José María Ramos Mejía" Buenos Aires, Argentina, C1221ADC Fundacion IDEAA Buenos Aires, Argentina, C1405CKC Hospital Italiano de Buenos Aires Buenos Aires, Argentina Australia, New South Wales St. Vincent's Hospital Sydney, New South Wales, Australia, 2010 Germany Johann Wolfgang Goethe-University Hospital, Medical HIVCENTER Frankfurt, Frankfurt am Main, Germany, 60590 Thailand Chulalongkorn University Hospital Bangkok, Thailand, 10330 Less <<
NCT00089505 HIV Infections Phase 3 Completed - Botswana ... More >> The Gaborone BHP Study Clinic Bontleng, Gaborone, Botswana Molepolole BHP Study Clinic, Scottish Livingstone Hospital Bontleng Gaborone, Botswana Kenya Moi University International Clnical Trials Unit Eldoret, Kenya, 30100 KMRI / Walter Reed Project Clinical Research Center Kericho, Kenya Malawi University of North Carolina Project (UNC Project) Lilongwe, Malawi, (265) 175-5056 South Africa University of KwaZulu Natal Durban, KZN, South Africa, 4013 Chris Hani Baragwanath Hospital, Johannesburg Johannesburg, South Africa University of Witwatersrand Johannesburg, South Africa Uganda Joint Clinical Research Centre (JCRC) Kampala, Uganda Zambia Centre for Infectious Disease Research in Zambia (CIDRZ) Lusaka, Zambia Zimbabwe University of Zimbabwe Avondale, Harare, Zimbabwe Less <<
NCT00034086 HIV Infections Not Applicable Completed - United States, Colorado ... More >> University of Colorado Hospital CRS Aurora, Colorado, United States United States, Illinois Rush Univ. Med. Ctr. ACTG CRS Chicago, Illinois, United States, 60612 United States, Ohio Case CRS Cleveland, Ohio, United States, 44106 Less <<
NCT00753324 HIV Infections Phase 4 Completed - Zambia ... More >> CIDRZ Lusaka, Zambia, 34681 Less <<
NCT00955968 - Completed - -
NCT00089505 - Completed - -
NCT02140255 HIV Infection Phase 1 Phase 2 Recruiting April 1, 2022 -
NCT00658346 - Completed - Cameroon ... More >> Hôpital Central Yaounde, Cameroon Hôpital de la CNPS Yaounde, Cameroon Less <<
NCT00665847 HIV-1 Phase 2 Completed - -
NCT03256422 HIV Infections Phase 3 Active, not recruiting December 2020 -
NCT01923311 - Terminated - -
NCT00955968 HIV Infection Phase 4 Completed - -
NCT01232361 - Completed - United States, Alabama ... More >> Univ. of Alabama Birmingham NICHD CRS (5096) Birmingham, Alabama, United States, 35294 United States, California Miller Children's Hospital Long Beach (5093) Long Beach, California, United States, 90806 Usc La Nichd Crs (5048) Los Angeles, California, United States, 90033 UCLA-Los Angeles/Brazil AIDS Consortium (LABAC) CR (3601) Los Angeles, California, United States, 90095 Univ of California, San Diego (UCSD) (4601) San Diego, California, United States, 92103 United States, Colorado Childrens Hospital (U. Colorado, Denver) NICHD CRS (5052) Denver, Colorado, United States, 80218-1088 United States, District of Columbia Children's National Med. Ctr. Washington DC NICHD CRS (5015) Washington, District of Columbia, United States, 20010 United States, Florida South Florida CDC Ft Lauderdale NICHD CRS (5055) Ft Lauderdal, Florida, United States, 33316 Univ of Miami Pediatric/Perinatal HIV/AIDS (4201) Miami, Florida, United States, 33136 United States, Illinois Chicago Children's CRS (4001) Chicago, Illinois, United States, 60611 Rush University Cook County Hospital NICHD CRS (5083) Chicago, Illinois, United States, 60612 United States, Maryland Johns Hopkins University NICHD CRS (5092) Baltimore, Maryland, United States, 21287 United States, Massachusetts Boston Medical Center Ped. HIV Program NICHD CRS (5011) Boston, Massachusetts, United States, 02118 WNE Maternal Pediatric Adolescent AIDS CRS (7301) Worcester, Massachusetts, United States, 01605 United States, Michigan Wayne State University/Children's Hospital of Michigan NICHD CRS (5041) Detroit, Michigan, United States, 48201 United States, New York Jacobi Med. Ctr. Bronx NICHD CRS (5013) Bronx, New York, United States, 10461 New York University NY (5012) New York, New York, United States, 10016 Columbia IMPAACT Center (4101) New York, New York, United States, 10032 SUNY Stony Brook (5040) Stony Brook, New York, United States, 11794-8111 United States, Tennessee St. Jude Childrens Research Hospital, Memphis (6501) Memphis, Tennessee, United States, 38105-2794 United States, Texas Texas Children's Hosp. CRS (3801) Houston, Texas, United States, 77030 Puerto Rico San Juan City Hosp. PR NICHD CRS (5031) San Juan, Puerto Rico, 00927 Less <<
NCT00445146 HIV Infections Phase 2 Completed - -
NCT01923311 Acquired Immune Deficiency Syn... More >>drome (AIDS) HIV Infections Less << Phase 2 Phase 3 Terminated - United States, Colorado ... More >> University of Colorado Denver Aurora, Colorado, United States, 80045 United States, North Carolina Duke University Medical Center Durham, North Carolina, United States, 27710 United States, Tennessee St. Jude Children's Research Hospital Memphis, Tennessee, United States, 38105 Italy Universita degli Studi di Pavia - Fondazione IRCCS Policlinico San Matteo Pavia, Italy, 27100 South Africa Be Part Yoluntu Centre Cape Town, South Africa, 7646 Rahima Moosa Mother and Child Hopsital Johannesburg, South Africa, 2112 Spain Hospital Universitario De Getafe Getafe, Madrid, Spain, 28095 Hospital 12 de Octubre Madrid, Spain, 28041 Thailand Thai Red Cross AIDS Research Centre (HIV-NAT) Bangkok, Thailand, 10330 Siriraj Hospital Bangkok, Thailand, 10700 Uganda Joint Clinical Research Centre Kampala, Uganda Less <<
NCT00234091 HIV Infections Phase 3 Completed - Cambodia ... More >> National Pediatric Hosp., Cambodia CIPRA CRS Phnom Penh, Cambodia Social Health Clinic, Cambodia CIPRA CRS Phnom Penh, Cambodia Thailand Hiv-Nat Cipra Crs Pathumwan, Bangkok, Thailand, 10330 Chiang Rai Regional Hosp. CIPRA CRS Muang, Chiang Rai, Thailand, 57000 Prapokklao Hosp. CIPRA CRS Chantaburi, Thailand, 22000 Nakornping Hosp. CIPRA CRS Chiang Mai, Thailand, 50180 Queen Savang Vadhana Memorial Hosp. CIPRA CRS Chonburi, Thailand, 20110 Srinagarind Hosp. CIPRA CRS Khon Kaen, Thailand, 40002 Bamrasnaradura Institute CIPRA CRS Nonthaburi, Thailand, 11000 Less <<
NCT00069524 HIV Infections ... More >> Hyperlipidemia Less << Phase 1 Phase 2 Completed - United States, California ... More >> General Clinical Research Center, San Francisco General Hospital San Francisco, California, United States Less <<
NCT00445146 - Completed - -
NCT00074581 HIV Infections Phase 3 Completed - United States, Massachusetts ... More >> Fenway Community Health Ctr. CRS Boston, Massachusetts, United States, 02115 Botswana Gaborone CRS Gaborone, Botswana Brazil Hospital Geral de Nova Iguaçu CRS (HGNI CRS) Nova Iguacu, Rio de Janeiro, Brazil, 26030-380 Hospital Nossa Senhora da Conceicao CRS Port Alegre, Rio Grande do Sul, Brazil, 91350 200 HSE-Hospital dos Servidores do Estado CRS Rio de Janeiro, Brazil, 20221-903 Instituto de Pesquisa Clinica Evandro Chagas (IPEC) CRS Rio de Janeiro, Brazil, 21040-360 India NARI Clinic at Gadikhana Dr. Kotnis Municipal Dispensary CRS Pune, Maharashtra, India, 411002 NARI Clinic at NIV CRS Pune, Maharashtra, India, 411011 NARI Pune CRS Pune, Maharashtra, India, 411026 Chennai Antiviral Research and Treatment (CART) CRS Chennai, Tamil Nadu, India, 600113 Kenya Kisumu Crs Kisumu, Nyanza, Kenya, 40100 Malawi Blantyre CRS Blantyre, Malawi Malawi CRS Lilongwe, Malawi South Africa Soweto HPTN CRS Johannesburg, Gauteng, South Africa, 2001 Wits Helen Joseph Hospital CRS (Wits HJH CRS) Johannesburg, Gauteng, South Africa, 2092 Thailand CMU HIV Prevention CRS Chiang Mai, Thailand, 50202 Zimbabwe Parirenyatwa CRS Harare, Zimbabwe Less <<
NCT00032669 HIV Infections Phase 1 Completed - United States, Maryland ... More >> National Cancer Institute (NCI) Bethesda, Maryland, United States, 20892 Less <<
NCT00074581 - Completed - -
NCT00043641 - Completed - United States, Maryland ... More >> National Institutes of Health Clinical Center, 9000 Rockville Pike Bethesda, Maryland, United States, 20892 Less <<
NCT01908660 - Completed - Spain ... More >> Hospital Universitario de Valme Seville, Spain, 41014 Less <<
NCT01543035 HIV Infection Phase 3 Completed - Switzerland ... More >> Universitätsspital Basel Klinik für Infektiologie & Spitalhygiene Bale, Switzerland, 4031 Inselspital PKT2B / Poliklinik für Infektiologie Berne, Switzerland, 3010 HUG /Division des Maladies infectieuses Unité VIH/SIDA Geneva, Switzerland, 1211 Hôpital Neuchâtelois - La Chaux-de-Fonds Service des Maladies infectieuses La Chaux-de-Fonds, Switzerland, 2300 CHUV / Service des maladies infectieuses Médecine 2 Lausanne, Switzerland, 1011 Kantonsspital / Infektiologie und Spitalhygiene Departement Innere Medizin St Gallen, Switzerland, 9007 Universitätsspital Zürich Division of Infectious Diseases and Hospital Epidemiology Department of Internal Medicine Zurich, Switzerland, 8091 Less <<
NCT02180438 - Completed - -
NCT02180438 HIV-2 Infection Phase 4 Completed - Senegal ... More >> Clinique des Maladies Infectieuses Ibrahima DIOP Mar/CRCF, Centre Hospitalier Universitaire de Fann Dakar, Senegal Less <<
NCT02102048 HIV Not Applicable Unknown July 2014 Italy ... More >> Department of Public Heath and Infectious Diseases. University of Rome "Sapienza" (Italy) Rome, Italy, 00161 Less <<
NCT00421473 HIV Infections ... More >> Malaria Less << Phase 4 Completed - Netherlands ... More >> Elisabeth hospital Tilburg, Brabant, Netherlands, 5022 GC Alysis Zorggroep loc. Rijnstate Arnhem, Gelderland, Netherlands, 6800 TA Radboud University Medical Centre Nijmegen Nijmegen, Gelderland, Netherlands, 6525 GA Leids Universitair Medisch Centrum Leiden, Zuid Holland, Netherlands, 2300 RC Erasmus MC Rotterdam, Zuid Holland, Netherlands, 3000 CA Less <<
NCT01717885 - Completed - Uganda ... More >> IDRC- Tororo Research Clinic and Tororo District Hospital Tororo, Uganda Less <<
NCT03642704 Mother to Child HIV Transmissi... More >>on Less << Phase 4 Recruiting September 2019 Guinea ... More >> Hôpital National Ignace Deen Recruiting Conakry, Guinea Contact: Aurélie Martin, MD       resp.rechercheoperationelle@solthis.org Less <<
NCT00004855 HIV Infections Not Applicable Completed - United States, California ... More >> Univ of Southern California / LA County USC Med Ctr Los Angeles, California, United States, 900331079 United States, Colorado Denver Dept of Health and Hosps Denver, Colorado, United States, 80262 Univ of Colorado Health Sciences Ctr Denver, Colorado, United States, 80262 United States, Hawaii Univ of Hawaii Honolulu, Hawaii, United States, 96816 United States, Illinois Northwestern Univ Med School Chicago, Illinois, United States, 60611 Cook County Hosp Chicago, Illinois, United States, 60612 Rush Presbyterian - Saint Luke's Med Ctr Chicago, Illinois, United States, 60612 United States, Indiana Indiana Univ Hosp Indianapolis, Indiana, United States, 462025250 Division of Inf Diseases/ Indiana Univ Hosp Indianapolis, Indiana, United States, 46202 Methodist Hosp of Indiana / Life Care Clinic Indianapolis, Indiana, United States, 46202 United States, Maryland Johns Hopkins Hosp Baltimore, Maryland, United States, 21287 United States, Massachusetts Beth Israel Deaconess - West Campus Boston, Massachusetts, United States, 02215 United States, New York Beth Israel Med Ctr New York, New York, United States, 10003 Bellevue Hosp / New York Univ Med Ctr New York, New York, United States, 10016 Mount Sinai Med Ctr New York, New York, United States, 10029 Univ of Rochester Medical Center Rochester, New York, United States, 14642 United States, North Carolina Univ of North Carolina Chapel Hill, North Carolina, United States, 275997215 Duke Univ Med Ctr Durham, North Carolina, United States, 27710 United States, Ohio Univ of Cincinnati Cincinnati, Ohio, United States, 452670405 Case Western Reserve Univ Cleveland, Ohio, United States, 44106 MetroHealth Med Ctr Cleveland, Ohio, United States, 441091998 United States, Rhode Island Miriam Hosp / Brown Univ Providence, Rhode Island, United States, 02906 United States, Texas Univ of Texas Galveston Galveston, Texas, United States, 775550435 Less <<
NCT03519503 - Recruiting December 30, 2018 Burkina Faso ... More >> Centre Hospitalier Universitaire Blaise Compraore Recruiting Ouagadougou, Burkina Faso Contact: Souleymane TASSEMBEDO, MD          South Africa Cecilia Makiwane hospital Recruiting East London, South Africa Contact: Mandisa SINGATA, PhD          Uganda PROMISE M&S site Recruiting Mbale, Uganda Contact: Grace N'DEEZI, MD,PhD          Zambia Paediatric Center Of Excellence Recruiting Lusaka, Zambia Contact: Mwiya MWIYA, MD Less <<
NCT03314064 Infection, Human Immunodeficie... More >>ncy Virus Less << Phase 4 Active, not recruiting October 31, 2018 Russian Federation ... More >> GSK Investigational Site Ekaterinburg, Russian Federation, 620149 GSK Investigational Site Kazan, Russian Federation, 420061 GSK Investigational Site Kemerovo, Russian Federation, 650056 GSK Investigational Site Krasnodar, Russian Federation, 350015 GSK Investigational Site Moscow, Russian Federation, 105275 GSK Investigational Site N.Novgorod, Russian Federation, 603005 GSK Investigational Site Orel, Russian Federation, 302040 GSK Investigational Site Smolensk, Russian Federation, 214006 GSK Investigational Site St. Petersburg, Russian Federation, 190103 GSK Investigational Site St. Petersburg, Russian Federation, 196645 GSK Investigational Site Toliyatti, Russian Federation, 445846 Less <<
NCT00719602 HIV Infections ... More >> Malaria Less << Early Phase 1 Completed - Malawi ... More >> University of North Carolina Lilongwe (12001) Lilongwe, Malawi Uganda Makerere University - JHU Research Collaboration (30293) Kampala, Uganda Zambia George Clinic CRS (30273) Lusaka, Zambia Less <<
NCT01054586 - Completed - -
NCT00307502 HIV Infections Phase 1 Completed - Spain ... More >> Germans Trias i Pujol Hospital Badalona, Barcelona, Spain, 08916 Hospital de Figueres Figueras, Barcelona, Spain, 17600 Fundació Hospital-Asil de Granollers Granollers, Barcelona, Spain, 08400 Hospital de Vic Vic, Barcelona, Spain, 08500 Hospital Universitari Sant Joan de Reus Reus, Tarragona, Spain, 43201 Hospital de la Santa Creu i Sant Pau Barcelona, Spain, 08025 Less <<
NCT00411957 HIV Infections Phase 1 Phase 2 Completed - Thailand ... More >> HIV-NAT, Thai Red Cross AIDS Research Center Bangkok, Thailand, 10300 Less <<
NCT00312754 HIV Infections Phase 4 Terminated(insufficient enroll... More >>ment) Less << - France ... More >> Local Institution Bobigny, France, 93009 Local Institution Le Kremlin Bicetre, France, 94270 Local Institution Paris Cedex 15, France, 75908 Local Institution Paris Cedex 20, France, 75970 Local Institution Paris, France, 75651 Local Institution Paris, France, 75877 Less <<
NCT00884793 - Completed - -
NCT02341274 Bioequivalence Phase 1 Completed - United States, Indiana ... More >> Indiana CTSI Clinical Research Center Indianapolis, Indiana, United States, 46202 Less <<
NCT02269917 Human Immunodeficiency Virus T... More >>ype 1 Less << Phase 3 Active, not recruiting March 31, 2020 -
NCT01054586 - Completed - -
NCT00884793 HIV Infections Not Applicable Completed - United States, California ... More >> San Francisco General Hospital San Francisco, California, United States, 94110 San Francisco VA Medical Center (SFVAMC) San Francisco, California, United States, 94121 Less <<
NCT00028314 HIV Infections ... More >> Lipodystrophy Wasting Disease Less << Not Applicable Completed - -
NCT00120393 HIV Infections Phase 3 Completed - United States, Arizona ... More >> Local Institution Phoenix, Arizona, United States United States, California Local Institution Bakersfield, California, United States Local Institution Los Angeles, California, United States Local Institution San Francisco, California, United States United States, Florida Local Institution Miami, Florida, United States United States, Massachusetts Local Institution Boston, Massachusetts, United States United States, New York Local Institution New York, New York, United States United States, Ohio Local Institution Cincinnati, Ohio, United States United States, Oregon Local Institution Portland, Oregon, United States United States, Pennsylvania Local Institution Philadelphia, Pennsylvania, United States United States, South Carolina Local Institution Columbia, South Carolina, United States United States, Texas Local Institution Dallas, Texas, United States Canada, Ontario Local Institution Hamilton, Ontario, Canada Canada, Quebec Local Institution Montreal, Quebec, Canada Less <<
NCT02269917 - Active, not recruiting - -
NCT00307151 HIV Infections Phase 2 Completed - India ... More >> BJ Medical College CRS Pune, Maharashtra, India, 411001 Malawi University of North Carolina Lilongwe CRS Mzimba Road, Lilongwe, Malawi South Africa Nelson R. Mandela School of Medicine, University of Kwazulu Natal, Durban, South Africa, 50202 University of Stellenbosch-Tygerberg Hospital, South Africa Cape Town, South Africa, 7700 Harriet Shezi Clinic at Chris Hani Baragwanath Hospital Johannesburg, South Africa, 2013 Perinatal HIV Research Unit, Chris Hani Baragwanath Hospital Johannesburg, South Africa Tanzania Kilimanjaro Christian Medical CRS IDC Research Offices, Moshi, Tanzania Uganda Makerere University Kampala, Uganda Zambia George Clinic CRS Lusaka, Zambia Zimbabwe UZ-College of Health Sciences Harare, Zimbabwe Less <<
NCT02383849 - Enrolling by invitation March 2020 South Africa ... More >> Soweto IMPAACT CRS (8052) Johannesburg, Gauteng, South Africa, 1862 Family Clinical Research Unit (FAM-CRU) CRS (8950) Tygerberg, Western Cape Province, South Africa, 7505 Less <<
NCT02116660 HIV Infections Phase 2 Completed - -
NCT00075907 HIV Infections Phase 3 Completed - United States, California ... More >> Usc La Nichd Crs Alhambra, California, United States, 91803 Long Beach Memorial Med. Ctr., Miller Children's Hosp. Long Beach, California, United States, 90806 Children's Hospital of Los Angeles NICHD CRS Los Angeles, California, United States, 90027 United States, Colorado Univ. of Colorado Denver NICHD CRS Aurora, Colorado, United States, 80045 United States, Illinois Chicago Children's CRS Chicago, Illinois, United States, 60614 United States, Louisiana Tulane/LSU Maternal/Child CRS New Orleans, Louisiana, United States, 70112 Children's Hosp. New Orleans, Louisiana, United States, 70118 United States, Maryland Johns Hopkins Hosp. & Health System - Dept. of Peds., Div. of Infectious Diseases Baltimore, Maryland, United States, 21287 United States, New York Bronx-Lebanon Hosp. IMPAACT CRS Bronx, New York, United States, 10457 SUNY Stony Brook NICHD CRS Stony Brook, New York, United States, 11794 United States, Tennessee St. Jude/UTHSC CRS Memphis, Tennessee, United States, 38105 United States, Texas Children's Med. Ctr. Dallas Dallas, Texas, United States, 75235 Texas Children's Hosp. CRS Houston, Texas, United States, 77030 Less <<
NCT00042289 HIV Infections Phase 4 Recruiting September 30, 2019 -
NCT00977756 - Completed - -
NCT02369406 HIV Pediatric... More >> AIDS Less << Phase 2 Phase 3 Recruiting February 2019 United States, Massachusetts ... More >> Harvard School of Public Health Active, not recruiting Boston, Massachusetts, United States, 02115 Brigham and Women's Hospital Active, not recruiting Cambridge, Massachusetts, United States, 02139 Ragon Institute of MGH, MIT and Harvard Active, not recruiting Cambridge, Massachusetts, United States, 02139 Botswana Botswana Harvard HIV/AIDS Institute Partnership Recruiting Gaborone, Botswana Contact: Joseph Makhema, MD    +267-390-2671    jmakhema@bhp.org.bw    Sub-Investigator: Joseph Makhema, MD Less <<
NCT00979706 HIV Phase 4 Completed - Spain ... More >> Hospital Clinic de Barcelona Barcelona, Spain, 08036 Less <<
NCT00017992 HIV Infections Phase 2 Unknown - United States, California ... More >> USC School of Medicine / LA County Med Ctr Active, not recruiting Los Angeles, California, United States, 90033 United States, Florida Univ of Florida Health Science Ctr / Pediatrics Active, not recruiting Jacksonville, Florida, United States, 32209 Univ of Miami Active, not recruiting Miami, Florida, United States, 331016960 United States, New York Bronx Municipal Hosp Ctr/Jacobi Med Ctr Active, not recruiting Bronx, New York, United States, 10461 New York Hosp / Cornell Med Ctr Active, not recruiting New York, New York, United States, 10021 St Luke's - Roosevelt Hosp Ctr Active, not recruiting New York, New York, United States, 10025 State Univ of New York at Stony Brook Active, not recruiting Stony Brook, New York, United States, 117948111 United States, Tennessee Saint Jude Children's Research Hosp of Memphis Active, not recruiting Memphis, Tennessee, United States, 381052794 Argentina Fundacion HUES Active, not recruiting Buenos Aires, Argentina Mexico Instituto Mexicano de Investigacion Clinica Active, not recruiting Col Roma, Mexico Panama Hospital del Nino Active, not recruiting Panama City, Panama Puerto Rico Univ of Puerto Rico / Med Science Campus Active, not recruiting San Juan, Puerto Rico, 00936 South Africa Perinatal HIV Research UNIT Recruiting Diepkloof, South Africa Contact: Dr. Avy Violari    011+27 11 989 9700    violari@mweb.co.za    Infectious Diseases Clinincal Trial Unit Recruiting Gaunteng, South Africa Contact: Pauline Francesca Conradie    011+ 27 11 717 2810    francesca_conradie@witshealth.co.za Less <<
NCT00006144 HIV Infections Phase 2 Completed - -
NCT00307151 - Completed - -
NCT03394196 HIV-2 Infection Not Applicable Recruiting July 2021 Senegal ... More >> Centre de Sante de Ziguinchor Not yet recruiting Ziguinchor, Casamance, Senegal Contact: Ibrahima Sall, PhD    221 77 645 3779       Clinique des Maladies Infectieuses Ibrahima DIOP Mar/CRCF, Centre Hospitalier Universitaire de Fann Recruiting Dakar, Senegal Contact: Moussa Seydi, MD    221 33 869 18 88    seydi.moussa@gmail.com    Principal Investigator: Moussa Seydi, MD Less <<
NCT02712801 HIV/AIDS and Infections Phase 4 Recruiting December 2018 China, Guangdong ... More >> Maternal and Child Health Hospital of Guangdong Province Recruiting Guangzhou, Guangdong, China Contact: Jiying Wen          China, Guangxi Maternal and Child Health Hospital of Guangxi Zhuang Autonomous Region Recruiting Nanning, Guangxi, China Contact: Xiaoxia Qiu          China, Sichuan Maternal and Child Health Hospital of Sichuan Province Recruiting Chengdu, Sichuan, China Contact: Gang Zhang          China, Xinjiang Maternal and Child Health Hospital of Xinjiang Uygur Autonomous Region Recruiting Urumqi, Xinjiang, China Contact: Lei Wang          China, Yunnan Maternal and Child Health Hospital of Yunan Province Recruiting Kunming, Yunnan, China Contact: Yan Zhang Less <<
NCT01632891 HIV-1 Infection ... More >> Pf Subclinical Parasitemia Less << Phase 1 Phase 2 Completed - Kenya ... More >> AMPATH at Moi Univ. Teaching Hosp. Eldoret CRS (12601) Eldoret, Kenya, 30100 Walter Reed Project - Kenya Med. Research Institute Kericho CRS (12501) Kericho, Kenya, 20200 Malawi College of Med. JHU CRS (30301) Blantyre, Malawi University of North Carolina Lilongwe CRS (12001) Lilongwe, Malawi Uganda Joint Clinical Research Centre (JCRC) (12401) Kampala, Uganda Less <<
NCT01516970 Human Immunodeficiency Virus (... More >>HIV) Less << Phase 3 Completed - Germany ... More >> Berlin, Germany Bonn, Germany Dortmund, Germany Dresden, Germany Düsseldorf, Germany Erlangen, Germany Frankfurt, Germany Freiburg, Germany Hamburg, Germany Köln, Germany Magdeburg, Germany Mainz, Germany Mannheim, Germany München, Germany Regensburg, Germany Stuttgart, Germany Ulm, Germany Less <<
NCT01516970 - Completed - -
NCT00573001 HIV Infections Phase 3 Completed - Cameroon ... More >> Hopital Central Yaounde, Cameroon Senegal Hopital de Fann Dakar, Senegal Less <<
NCT00708162 HIV Infection Phase 3 Completed - -
NCT00642291 HIV Infections Phase 2 Completed - Romania ... More >> Bucharest, Sector 2, Romania Bucharest, Sector 3, Romania Less <<
NCT00099632 - Completed - -
NCT00708162 - Completed - -
NCT00335192 HIV Phase 4 Completed - Spain ... More >> Hospital Universitari Germans Trias i Pujol Badalona, Barcelona, Spain, 08916 Less <<
NCT01737359 Human Immunodeficiency Virus I... More >>nfection Less << Phase 2 Terminated - Argentina ... More >> Research Site Rosario, Santa Fe, Argentina, S2000CXP Research Site Rosario, Santa Fe, Argentina, S2000PBJ Research Site Buenos Aires, Argentina, C1141ACG Research Site Buenos Aires, Argentina, C1202ABB Research Site Buenos Aires, Argentina, C1405CKC Research Site Buenos Aires, Argentina, C1426EGR Less <<
NCT01671982 HIV Phase 1 Completed - Thailand ... More >> Sanpatong Hospital Sanpatong, Chiang Mai, Thailand, 20120 HIV-NAT Bangkok, Thailand, 10330 Nakornping Hospital Chiang Mai, Thailand Chonburi Hospital Chonburi, Thailand, 20000 Phayao Hospital Phayao, Thailand, 56000 Less <<
NCT00162643 Acquired Immunodeficiency Synd... More >>rome Less << Phase 4 Unknown - Mexico ... More >> Hospital de Especialidades Centro Medico Nacional siglo XXI Recruiting Mexico City, D.f., Mexico, 06720 Contact: Leticia M Perez-Saleme, MD    5255-56-27 69 00 ext 21547    lepesa@prodigy.net.mx    Principal Investigator: Leticia M Perez-Saleme, MD          Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran Recruiting Mexico City, DF, Mexico, 14000 Contact: Angelina Villasis-Keever, MD MSc    5255-56559675    avkeever@prodigy.net.mx    Contact: Luis E. Soto-Ramirez, MD    5255-56559675    lsoto@quetzal.innsz.mx    Principal Investigator: Angelina Villasis-Keever, MD MSc          Sub-Investigator: Luis E Soto-Ramirez, MD          Hospital General Regional #53 Recruiting Los Reyes La Paz, Estado de Mexico, Mexico, 56400 Contact: Patricia Mendez-Cardos, MD    5255-5855 4414 ext 238    kalekbuda74@yahoo.com    Principal Investigator: Patricia Mendez-Cardos, MD          Hospital General Regional #72 Recruiting Tlalnepantla, Estado de Mexico, Mexico, 54000 Contact: Fernanda Gutierrez-Escolano, MD MSc    5255-5565 9210 ext 320    fernandamx@yahoo.com    Contact: Pueblito Pizano-Gonzalez, MD    5255-5565 9210 ext 320       Principal Investigator: Fernanda Gutierrez-Escolano, MD MSc          Sub-Investigator: Pueblito Pizano-Gonzalez, MD          Hospital General Regional de Leon Recruiting Leon, Guanajuato, Mexico Contact: Juan L Mosqueda-Gomez, MD    5255-4771310037    luis_mosqueda@yahoo.com    Principal Investigator: Juan L Mosqueda-Gomez, MD Less <<
NCT00099632 HIV Infections Phase 2 Completed - Haiti ... More >> Les Centres GHESKIO Clinical Research Site (GHESKIO-INLR) CRS Port-au-Prince, Haiti, 6110 India Byramjee Jeejeebhoy Government Medical College CRS Pune, Maharashtra, India, 411001 Chennai Antiviral Research and Treatment (CART) CRS Chennai, Tamil Nadu, India, 600113 Malawi Blantyre CRS Blantyre, Malawi South Africa Wits Helen Joseph Hospital CRS (Wits HJH CRS) Johannesburg, Gauteng, South Africa, 2092 Durban International CRS Westville, KwaZulu-Natal, South Africa, 3610 Tanzania Kilimanjaro Christian Medical CRS Moshi, Tanzania Uganda Joint Clinical Research Center (JCRC)/Kampala CRS Kampala, Uganda Less <<
NCT01705873 - Unknown August 2013 Argentina ... More >> Helios Salud Recruiting Buenos Aires, Argentina, 1141 Contact: Diego M Cecchini, PhD    54 11 4896 1868 ext 116    dcecchini@heliossalud.com.ar Less <<
NCT01583439 HIV Infections Not Applicable Terminated(Low Accrual.) - Botswana ... More >> Deborah Retief Memorial Hospital Mochudi, Botswana Less <<
NCT00476983 Saquinavir/Ritonavir BID or Lo... More >>pinavir/Ritonavir BID Less << Phase 2 Phase 3 Withdrawn(No funding) - -
NCT00978068 Malaria HIV I... More >>nfections Less << Phase 3 Completed - Uganda ... More >> IDRC - Tororo Research Clinic Tororo, Uganda Less <<
NCT00100646 HIV Infections Not Applicable Completed - South Africa ... More >> University of the Witwatersrand Johannesburg, South Africa Less <<
NCT00624195 HIV Infections Phase 2 Phase 3 Completed - United States, California ... More >> HIV Neurobehavioral Research Center, University of California San Diego San Diego, California, United States, 92103 University of California, San Francisco San Francisco, California, United States, 94110 United States, Maryland Johns Hopkins University- School of Medicine Baltimore, Maryland, United States, 21287 United States, Missouri Washington University St. Louis, Missouri, United States, 63110 United States, New York Mount Sinai Medical Center New York, New York, United States, 10024 Less <<
NCT00454337 HIV Infections Phase 3 Completed - France ... More >> Service des maladies infectieuses et tropicales Hopital Saint Louis Paris, France, 75010 Less <<
NCT01450618 - Completed - -
NCT02404259 HIV Not Applicable Completed - Thailand ... More >> Khon Kaen University Khon Kaen, Thailand, 40002 Less <<
NCT00122226 HIV Infections ... More >> HIV-Associated Lipodystrophy Syndrome Less << Phase 4 Unknown - Finland ... More >> Helsinki University Central Hospital Helsinki, Finland Netherlands Academic Medical Center Amsterdam, Netherlands Medisch Centrum Jan van Goyen Amsterdam, Netherlands Onze Lieve Vrouwe Gasthuis, location Oosterpark Amsterdam, Netherlands Onze Lieve Vrouwe Gasthuis, location Prinsengracht Amsterdam, Netherlands Slotervaart ziekenhuis Amsterdam, Netherlands VUMC Free University Medical Center Amsterdam, Netherlands Ziekenhuis Leyenburg den Haag, Netherlands Kennemer Gasthuis, location Elisabeth Haarlem, Netherlands Leids Universitair Medisch Centrum Leiden, Netherlands Erasmus Universitair Medisch Centrum Rotterdam, Netherlands Spain Hospital Clinic Barcelona, Spain United Kingdom Royal Free Hospital London, United Kingdom Less <<
NCT00624195 - Completed - -
NCT00135434 HIV Infections Phase 1 Completed - United States, New Jersey ... More >> Clinical Pharmacology Unit, Bristol-Myers Squibb Company Hamilton, New Jersey, United States, 08690 Less <<
NCT00318123 HIV Infections Phase 3 Completed - Italy ... More >> Institute of Infections and Tropical Diseases University of Brescia Brescia, Italy, 25125 Spain Hospital Arquitecto Marcide Ferrol, A Coruña, Spain, 15405 Hospital Generall de Alicante Alicante, Alacant, Spain, 03010 Hospital Universitari Germans Trias i Pujol Badalona, Barcelona, Spain, 08916 Hospital de Granollers Granollers, Barcelona, Spain, 08400 Hospital Universitario de Canarias Santa Cruz de Tenerife, Canarias, Spain, 38320 Hospital Clínico Universitario de Santiago Santiago de Compostela, Galicia, Spain, 15706 Hopsital Costa del Sol Marbella, Malaga, Spain, 29600 Hospital Nuestra Sra del Rosell Cartagena, Murcia, Spain, 30203 Hospital Central de Asturias Asturias, Oviedo, Spain, 33006 Hospital Xeral de Vigo Vigo, Pontevedra, Spain, 36204 Hospital Virgen de las Nieves Granada, Spain, 18014 Hopsital Gregorio Marañón Madrid, Spain, 28007 Hospital 12 de Octubre Madrid, Spain, 28041 Hospital General de Murcia Murcia, Spain, 30003 Hospital Virgen Macarena Sevilla, Spain, 41009 Hospital Virgen del Rocío Sevilla, Spain, 41013 Hospital de Tarragona Tarragona, Spain, 43007 Hospital Universitari Dr. Peset Valencia, Spain, 46017 Hospital Miguel Servet Zaragoza, Spain, 50009 Less <<
NCT01352715 HIV-1 Infection Phase 3 Completed - Brazil ... More >> Instituto de Pesquisa Clinica Evandro Chagas (12101) Rio de Janeiro, Brazil, 21045 India BJ Medical College CRS (31441) Pune, Maharashtra, India, 411001 NARI Pune CRS Pune, Maharashtra, India Y.R.G Ctr, for AIDS Research and Education (11701) Chennai, India Kenya AMPATH at Moi Univ. Teaching Hosp. Eldoret CRS (12601) Eldoret, Kenya, 30100 Malawi College of Med. JHU CRS (30301) Blantyre, Malawi University of North Carolina Lilongwe CRS (12001) Lilongwe, Malawi Peru San Miguel CRS San Miguel, Lima, Peru Barranco CRS (11301) Lima, Peru, 18 PE South Africa Wits HIV CRS (11101) Johannesburg, Gauteng, South Africa Durban Adult HIV CRS (11201) Durban, South Africa, 4013 SF Soweto ACTG CRS (12301) Johannesburg, South Africa Univ. of Witwatersrand CRS (11101) Johannesburg, South Africa Tanzania Kilimanjaro Christian Medical CRS Kilimanjaro Region, Moshi, Tanzania Thailand Chiang Mai University ACTG CRS (11501) Chiang Mai, Thailand, 50202 Zimbabwe UZ-Parirenyatwa CRS (30313) Harare, Zimbabwe Less <<
NCT03227653 - Completed - Tanzania ... More >> Kilimanjaro Christian Medical Centre Moshi, Kilimanjaro Region, Tanzania, 3010 Mawenzi Regional Hospital Moshi, Kilimanjaro Region, Tanzania, 3054 Kibosho Hospital Kibosho, Tanzania Kiboroloni Dispensary Moshi, Tanzania Majengo Health Centre Moshi, Tanzania Pasua Health Centre Moshi, Tanzania Less <<
NCT00836212 Human Immunodeficiency Virus ... More >> HIV Infections Less << Phase 4 Unknown April 2009 Switzerland ... More >> University Hopistal of Geneva Recruiting Geneva, Switzerland, 1211 Contact: Alexandra AC Calmy, MD    022 372 98 08 ext +41    Alexandra.Calmy@hcuge.ch    Principal Investigator: Bernard BH Hirschel, MD          Principal Investigator: Alexandra AC Calmy, MD Less <<
NCT00978237 HIV Infections ... More >> Lipoatrophy Less << Phase 4 Completed - Spain ... More >> Hospital de Bellvitge L'Hospitalet de LLobregat, Barcelona, Spain Hospital Universitario Central de Asturias Asturias, Spain Hospital Clínic de Barcelona Barcelona, Spain Hospital de la Santa Creu i Sant Pau de Barcelona Barcelona, Spain Hospital Clínico San Carlos Madrid, Spain Hospital La Fe Valencia, Spain Hospital Xeral-Cíes Vigo, Spain Less <<
NCT00100984 HIV Infection Phase 4 Terminated(Insufficient enroll... More >>ment) Less << - United States, Alabama ... More >> Hobson City, Alabama, United States, 36201 United States, California Los Angeles, California, United States, 90033 Los Angeles, California, United States, 90036 United States, District of Columbia Washington, D.C., District of Columbia, United States, 20007 Washington, D.C., District of Columbia, United States, 20009 United States, Florida Orlando, Florida, United States, 32803 United States, Georgia Atlanta, Georgia, United States, 30308 Macon, Georgia, United States, 31201 United States, Illinois Chicago, Illinois, United States, 60612 Chicago, Illinois, United States, 60657 United States, Maryland Baltimore, Maryland, United States, 21201 United States, Massachusetts Boston, Massachusetts, United States, 02215-3318 United States, Mississippi Jackson, Mississippi, United States, 39216-4505 United States, Missouri Saint Louis, Missouri, United States, 63139 United States, New Jersey Newark, New Jersey, United States, 07103 United States, New York New York, New York, United States, 10011 New York, New York, United States, 10016 United States, North Carolina Huntersville, North Carolina, United States, 28078 United States, Texas Dallas, Texas, United States, 75246 Houston, Texas, United States, 77004 Less <<
NCT00050895 HIV Infections Phase 3 Completed - -
NCT01352715 - Completed - -
NCT00164736 HIV Infections Phase 3 Completed - Malawi ... More >> Kamuzu Central Hospital, Bottom Hospital Lilongwe, Malawi Less <<
NCT00342355 - Completed - -
NCT00405925 HIV Infections Phase 3 Completed - Netherlands ... More >> Rijnstate Hospital Arnhem, Gelderland, Netherlands, 6800 TA Less <<
NCT00342355 HIV Phase 4 Completed - South Africa ... More >> South African Military Health Services (SAMHS) Centurion, South Africa Umtata Sickbay Eastaern Cape, South Africa 3 Military Hospital Free State, South Africa 1 Military Hospital Gauteng, South Africa Mtubatuba SIckbay Kwazulu-Natal, South Africa Phalaborwa Sickbay Limpopo, South Africa 2 Military Hospital Western Cape, South Africa Less <<
NCT03070470 Drug-induced QT Prolongation ... More >> Pharmacokinetics Pharmacodynamics Less << Phase 1 Completed - United States, Wisconsin ... More >> Spaulding Clinical Research West Bend, Wisconsin, United States, 53095 Less <<
NCT02513147 HIV-1 Phase 4 Completed - Spain ... More >> Hospital Universitari Vall d'Hebron Barcelona, Spain, 08035 Less <<
NCT00993031 - Completed - -
NCT02219672 AIDS/HIV PROBLEM Phase 3 Unknown July 2017 China, Beijing ... More >> Peking Union Medical College Hospital Recruiting Beijing, Beijing, China, 100730 Contact: Fuping Guo, MD    86-10-69155082    pumchguofp@163.com    Principal Investigator: Taisheng Li, PhD Less <<
NCT00627055 HIV Infections Phase 4 Completed - Thailand ... More >> Chulalongkorn University Bangkok, Thailand, 10330 Hivnat, Trcarc Bangkok, Thailand, 10330 Siriraj Hospital Bangkok, Thailand, 10700 Ramathibodi Hospital Bangkok, Thailand Taksin Hospital Bangkok, Thailand Sanpatong Hospital Chiang Mai, Thailand Chiang Rai Regional Hospital Chiang Rai, Thailand Chonburi Hospital Chonburi, Thailand Khon Kaen University Khon Kaen, Thailand, 40002 Bamrasnaradura Institute Nonthaburi, Thailand, 11000 Less <<
NCT00993031 Malaria HIV I... More >>nfections Less << Phase 3 Completed - Uganda ... More >> Tororo District Hospital Tororo, Uganda Less <<
NCT00122590 HIV Infections Not Applicable Terminated - France ... More >> Service de Medecine Interne Hopital Cochin Paris, France, 75014 Less <<
NCT01003990 - Completed - -
NCT01003990 HIV Phase 3 Completed - -
NCT00988039 Human Immunodeficiency Virus ... More >> HIV Less << Phase 3 Completed - Kenya ... More >> AMPATH Centre at Moi Teaching Referral Hospital Eldoret, Kenya Malawi University of Malawi Blantyre, Malawi Mzuzu Central Hospital Mzuzu, Malawi Uganda Joint Clinical Research Centre Fort Portal, Uganda JCRC Gulu, Uganda JCRC Kabale, Uganda JCRC Kakira, Uganda Infectious Diseases Institute Kampala, Uganda Joint Clinical Research Centre Kampala, Uganda San Raphael of St Francis Hospital Nsambya Kampala, Uganda Joint Clinical Research Centre Mbale, Uganda Joint Clinical Research Centre Mbarara, Uganda Zambia University Teaching Hospital Lusaka, Zambia Zimbabwe University of Zimbabwe Clinical Research Centre Harare, Zimbabwe Less <<
NCT01154673 - Completed - -
NCT01480713 HIV-1 Infection Phase 3 Completed - Spain ... More >> Germans Trias i Pujol Hospital Badalona, Barcelona, Spain, 08916 Less <<
NCT01154673 Acute HIV Infection Phase 2 Phase 3 Completed - Canada, Ontario ... More >> University of Toronto Toronto, Ontario, Canada, M5B 1W8 Maple Leaf Medical Clinic Toronto, Ontario, Canada, M5G 1K2 Less <<
NCT00090779 - Terminated(The DSMB concluded ... More >>that the findings regarding the primary analysis would persist and that no additional study goals would be achieved by continuing the study.) Less << - -
NCT00028366 HIV Infections Not Applicable Completed - United States, California ... More >> USC CRS Los Angeles, California, United States, 90033-1079 Ucsf Aids Crs San Francisco, California, United States, 94110 United States, Georgia The Ponce de Leon Ctr. CRS Atlanta, Georgia, United States, 30308 United States, Indiana Indiana Univ. School of Medicine, Infectious Disease Research Clinic Indianapolis, Indiana, United States, 462025250 Indiana Univ. School of Medicine, Wishard Memorial Indianapolis, Indiana, United States, 46202 Methodist Hosp. of Indiana Indianapolis, Indiana, United States, 46202 United States, New York HIV Prevention & Treatment CRS New York, New York, United States United States, Ohio Univ. of Cincinnati CRS Cincinnati, Ohio, United States, 452670405 Case CRS Cleveland, Ohio, United States, 44106 MetroHealth CRS Cleveland, Ohio, United States, 441091998 The Ohio State Univ. AIDS CRS Columbus, Ohio, United States, 432101228 United States, Tennessee Vanderbilt Therapeutics CRS Nashville, Tennessee, United States, 37203 United States, Washington University of Washington AIDS CRS Seattle, Washington, United States, 98104 Less <<
NCT00949234 HIV Prevention ... More >> HIV Infections Less << Phase 2 Completed - United States, California ... More >> L.A. Gay & Lesbian Center Los Angeles, California, United States, 90028 OASIS Clinic Los Angeles, California, United States, 90059 Less <<
NCT00949234 - Completed - -
NCT01146873 HIV/AIDS HIV ... More >>Infections Less << Phase 3 Completed - South Africa ... More >> Rahima Moosa Mother and Child Hospital Johannesburg, Gauteng, South Africa Less <<
NCT01146873 - Completed - -
NCT00207948 - Terminated(no measurable respo... More >>nse was detected at the 50% increase threshold.) Less << - United States, District of Col... More >>umbia Children's National Medical Center Washington, District of Columbia, United States, 20010 Less <<
NCT00090779 HIV Infections Phase 2 Terminated(The DSMB concluded ... More >>that the findings regarding the primary analysis would persist and that no additional study goals would be achieved by continuing the study.) Less << - -
NCT00966160 Acquired Immunodeficiency Synd... More >>rome HIV Infections Less << Phase 3 Completed - Germany ... More >> Medical Clinic I and Department of Pharmacology, University of Cologne Cologne, Germany Less <<
NCT00294372 HIV Infections Phase 2 Terminated - Germany ... More >> Boehringer Ingelheim Investigational Site Berlin, Germany Boehringer Ingelheim Investigational Site Bochum, Germany Boehringer Ingelheim Investigational Site Bonn, Germany Boehringer Ingelheim Investigational Site Erlangen, Germany Boehringer Ingelheim Investigational Site Frankfurt/Main, Germany Boehringer Ingelheim Investigational Site Hamburg, Germany Boehringer Ingelheim Investigational Site Hannover, Germany Boehringer Ingelheim Investigational Site Heidelberg, Germany Boehringer Ingelheim Investigational Site Mainz, Germany Boehringer Ingelheim Investigational Site Munchen, Germany Boehringer Ingelheim Investigational Site Ulm, Germany Less <<
NCT00414518 HIV Infections Not Applicable Completed - United States, Colorado ... More >> University of Colorado Health Sciences Center Denver, Colorado, United States, 80262 United States, Georgia AIDS Research Consortium of Atlanta Atlanta, Georgia, United States, 30308 Zimbabwe University of Zimbabwe College of Health Sciences Harare, Zimbabwe Less <<
NCT00532168 HIV Infections Phase 4 Completed - Spain ... More >> Hospital Clinic Barcelona, Catalonia, Spain, 08036 Less <<
NCT00765154 HIV Phase 4 Terminated(Difficulties in rec... More >>ruitment due to a change in the nature of practice.) Less << - United Kingdom ... More >> Chelsea and Westminster Hospital London, United Kingdom, SW10 9TH Less <<
NCT00004583 HIV Infections Phase 3 Completed - -
NCT00640887 HIV Infections ... More >> Tuberculosis Less << Phase 2 Completed - South Africa ... More >> Unit for Clinical and Biomedical TB Research (Medical Research Council) Durban, South Africa, 4067 Less <<
NCT00044837 HIV Infections Phase 1 Terminated - United States, Maryland ... More >> Barbara Brizz Rockville, Maryland, United States, 20852 Less <<
NCT01445223 HIV Phase 4 Completed - Sweden ... More >> Department of Infectious Diseases Goteborg, Sweden, S-41685 Less <<
NCT00414518 - Completed - -
NCT01601626 - Terminated(The study was stopp... More >>ed early due to feasibility concerns.) Less << - -
NCT00945282 Infection, Human Immunodeficie... More >>ncy Virus Less << Phase 2 Completed - Argentina ... More >> GSK Investigational Site Buenos Aires, Argentina, B1602DBG Less <<
NCT01513122 HIV Phase 4 Completed - Argentina ... More >> CEADI Buenos Aires, Argentina India YRGCare Medical Centre Chennai, India, 600113 Malaysia University of Malaya Medical Centre Kuala Lumpur, Malaysia, 50603 South Africa JOSHA Research Bloemfontain, South Africa Desmond Tutu HIV Foundation Cape Town, South Africa, 7925 Chris Hani Baragwanath Hospital Soweto, South Africa Thailand HIV-NAT Program on AIDS - Thai Red Cross Bangkok, Thailand, 10330 Less <<
NCT01513122 - Completed - -
NCT02097381 HIV Infection Not Applicable Unknown December 2014 Italy ... More >> Department of Public Health and Infectious Diseases, University of Rome "Sapienza", Italy Rome, RM, Italy, 00161 Less <<
NCT01601626 HIV Infection ... More >> Tuberculosis Less << Phase 2 Terminated(The study was stopp... More >>ed early due to feasibility concerns.) Less << - Brazil ... More >> Hospital Nossa Senhora da Conceicao CRS (12201) Porto Alegre, RS, Brazil, 9043010 Instituto de Pesquisa Clinica Evandro Chagas (12101) Rio de Janeiro, Brazil, 21045 Haiti GHESKIO Institute of Infectious Diseases and Reproductive Health (GHESKIO - IMIS) CRS (31730) Port Au Prince, Haiti Les Centres GHESKIO CRS (30022) Port-au-Prince, Haiti, HT-6110 Kenya Moi University Clinical Research Center CRS (12601) Eldoret, Kenya, 30100 Peru Investigaciones Medicas en Salud (INMENSA) (11302) San Isidro, Lima, Peru Asociacion Civil Impacta Salud y Educacion - Miraf CRS (11301) Lima, Peru, 18 PE South Africa Wits HIV CRS (11101) Johannesburg, Gauteng, South Africa Durban Adult HIV CRS (11201) Durban, South Africa, 4013 SF Less <<
NCT00945282 - Completed - -
NCT00827112 - Completed - -
NCT00827112 Human Immunodeficiency Virus-1 Phase 2 Completed - -
NCT00443729 - Terminated(Primary efficacy an... More >>alysis at Week 24 did not demonstrate non-inferiority of raltegravir versus lopinavir (+) ritonavir) Less << - -
NCT00085943 HIV Infection ... More >> Infection, Human Immunodeficiency Virus Less << Phase 3 Completed - -
NCT00585793 - Completed - Uganda ... More >> Kampala, Uganda Less <<
NCT00443729 HIV Infection Phase 3 Terminated(Primary efficacy an... More >>alysis at Week 24 did not demonstrate non-inferiority of raltegravir versus lopinavir (+) ritonavir) Less << - -
NCT00038532 HIV Infections Phase 2 Completed - -
NCT01854762 HIV Pregnancy Phase 2 Phase 3 Recruiting July 2017 Brazil ... More >> Fundação Bahiana de Infectologia/SEI Recruiting Salvador, Bahia, Brazil, 40110-010 Contact: Estela Luz, RN, MSci    32838123    eluz5@yahoo.com.br    Sub-Investigator: Ana Gabriela A Travassos, MD, MSci          Sub-Investigator: Isabela Nobrega, MD, MSci Less <<
NCT00135395 HIV Infections Phase 3 Completed - -
NCT00038220 HIV Infections Phase 2 Completed - United States, New York ... More >> Aaron Diamond AIDS Research Center - Rockefeller University New York, New York, United States, 10021 Less <<
NCT00785616 HIV Infection Phase 4 Completed - United States, New York ... More >> Montefiore Medical Center Bronx, New York, United States, 10467 Less <<
NCT00936195 HIV Infection ... More >> Pregnancy Breastfeeding HIV Infections Less << Phase 3 Withdrawn(faillure to obtain i... More >>nsurance because of refusal from insurance companies) Less << June 2013 Côte D'Ivoire ... More >> Programme PAC-CI, site ANRS Abidjan, Côte D'Ivoire Zambia Center for Infectious Desease Reserach in Zambia Lusaka, Zambia Less <<
NCT00928187 HIV HIV Infec... More >>tions Less << Phase 3 Completed - Burkina Faso ... More >> Day Hospital, CHU Sanou Souro Bobo Dioulasso, Burkina Faso Cameroon Day Hospital, Central Hospital Yaounde, Cameroon Senegal Clinical Research and Training Center, Fann Hospital Dakar, Senegal Less <<
NCT00056641 HIV Infections Phase 2 Completed - -
NCT01296152 HIV-1 Infection Phase 2 Completed - United States, California ... More >> University of Southern California LA (5048) Los Angeles, California, United States, 90033 United States, District of Columbia Children's National Medical Center Washington DC NICHD CRS (5015) Washington, District of Columbia, United States, 20010 Washington Hospital Center NICHD CRS (5023) Washington, District of Columbia, United States, 20010 United States, Florida South Florida Childrens Diagnostic & Treatment Cen (5055) Ft. Lauderdale, Florida, United States, 33316 United States, Illinois Northwestern University CRS (2701) Chicago, Illinois, United States, 60611 Rush University Cook County Hospital Chicago NICHD CRS (5083) Chicago, Illinois, United States, 60612 United States, Louisiana Tulane University New Orleans NICHD CRS (5095) New Orleans, Louisiana, United States, 70112 United States, New York Univ. of Rochester ACTG CRS (1101) Rochester, New York, United States, 14642 SUNY Stony Brook NICHD CRS (5040) Stony Brook, New York, United States, 11794 United States, North Carolina Unc Aids Crs (3201) Chapel Hill, North Carolina, United States, 27516 United States, Ohio Univ. of Cincinnati CRS Cincinnati, Ohio, United States, 45267-0405 Univ. of Cincinnati CRS (2401) Cincinnati, Ohio, United States, 45267 United States, Washington University of Washington AIDS CRS (1401) Seattle, Washington, United States, 98104 Puerto Rico San Juan Hospital PR NICHD CRS (5031) San Juan, Puerto Rico, 00936 Less <<
NCT00023218 HIV Infections ... More >> Hepatitis C Less << Not Applicable Withdrawn - United States, Hawaii ... More >> Univ of Hawaii Honolulu, Hawaii, United States, 96816 Tripler Army Med Ctr Tripler AMC, Hawaii, United States, 96859 United States, New York Beth Israel Med Ctr New York, New York, United States, 10003 Less <<
NCT01296152 - Completed - -
NCT00109590 HIV Infections Phase 2 Completed - Thailand ... More >> Siriraj Hospital Mahidol University CRS Bangkok, Bangkoknoi, Thailand, 10700 Bhumibol Adulyadej Hosp. CRS Saimai, Bangkok, Thailand, 10220 Prapokklao Hosp. CRS Chantaburi, Thailand, 22000 Chiang Mai University Pediatrics-Obstetrics CRS Chiang Mai, Thailand, 50200 Chiangrai Prachanukroh Hospital CRS Chiangrai, Thailand, 57000 Chonburi Hosp. CRS Chonburi, Thailand, 20000 Phayao Provincial Hosp. CRS Phayao, Thailand, 56000 Less <<
NCT00004581 HIV Infections Phase 3 Completed - -
NCT00109590 - Completed - -
NCT01259219 Children With Confirmed HIV In... More >>fection Receiving ART Regimen Containing 2 NRTIs + LPV/RTV at Standard Dose Successfully Completed TB Treatment in the Past 2 to 6 Weeks of Enrollment Less << Phase 1 Unknown June 2012 South Africa ... More >> Harriet Shezi Children's Clinic, Chris Hani Baragwanath Hospital, WHI, University of the Witwatersrand Recruiting Johannesburg, Gauteng, South Africa, 1864 Contact: Hermien Gous, PharmD    27119388189    hermieng@witsecho.org.za    Harriet Shezi Children's Clinic, Chris Hani Baragwanath Hospital, WHI, University of the Witwatersrand Recruiting Johannesburg, Gauteng, South Africa, 1864 Principal Investigator: Henry (Harry) AJ Moultrie, MD          Harriet Shezi Children's Clinic Recruiting Johannesburg, Gauteng, South Africa Contact: Sonwabo Lindani, RN    27 11 933 9392    sonwabol@witsecho.org.za    Contact: Merleesa Govender    27 11 933 9630    merleesag@witsecho.org.za Less <<
NCT00928187 - Completed - -
NCT00302822 HIV Infections ... More >> AIDS Less << Phase 3 Completed - France ... More >> Service des Maladies Infectieuses A Hôpital Bichat-Claude Bernard Paris, France, 75018 Less <<
NCT00834457 AIDS-related Kaposi's Sarcoma Phase 2 Phase 3 Completed - Zimbabwe ... More >> University of Zimbabwe College of Health Sciences Department of Medicine Harare, Zimbabwe Less <<

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

1.59mL

0.32mL

0.16mL

7.95mL

1.59mL

0.80mL

15.90mL

3.18mL

1.59mL

References

[1]Vishnuvardhan D, Moltke LL, et al. Lopinavir: acute exposure inhibits P-glycoprotein; extended exposure induces P-glycoprotein. AIDS. 2003 May 2;17(7):1092-4.

[2]Sham HL, Kempf DJ, et al. ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease. Antimicrob Agents Chemother. 1998 Dec;42(12):3218-24.

[3]Ansari H, Singh P. Formulation and in-vivo Evaluation of Novel Topical Gel of Lopinavir for Targeting HIV. Curr HIV Res. 2018;16(4):270-279. doi: 10.2174/1570162X16666180924101650. PMID: 30246641; PMCID: PMC6416462.

[4]Hakim JG, Thompson J, Kityo C, Hoppe A, Kambugu A, van Oosterhout JJ, Lugemwa A, Siika A, Mwebaze R, Mweemba A, Abongomera G, Thomason MJ, Easterbrook P, Mugyenyi P, Walker AS, Paton NI; Europe Africa Research Network for Evaluation of Second-line Therapy (EARNEST) Trial Team. Lopinavir plus nucleoside reverse-transcriptase inhibitors, lopinavir plus raltegravir, or lopinavir monotherapy for second-line treatment of HIV (EARNEST): 144-week follow-up results from a randomised controlled trial. Lancet Infect Dis. 2018 Jan;18(1):47-57. doi: 10.1016/S1473-3099(17)30630-8. Epub 2017 Nov 3. PMID: 29108797; PMCID: PMC5739875.

[5]Rebello KM, Andrade-Neto VV, Zuma AA, Motta MCM, Gomes CRB, de Souza MVN, Atella GC, Branquinha MH, Santos ALS, Torres-Santos EC, d'Avila-Levy CM. Lopinavir, an HIV-1 peptidase inhibitor, induces alteration on the lipid metabolism of Leishmania amazonensis promastigotes. Parasitology. 2018 Sep;145(10):1304-1310. doi: 10.1017/S0031182018000823. Epub 2018 May 28. PMID: 29806577; PMCID: PMC6137378.

[6]Gratton R, Tricarico PM, Guimaraes RL, Celsi F, Crovella S. Lopinavir/Ritonavir Treatment Induces Oxidative Stress and Caspaseindependent Apoptosis in Human Glioblastoma U-87 MG Cell Line. Curr HIV Res. 2018;16(2):106-112. doi: 10.2174/1570162X16666180528100922. PMID: 29804534.

 

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