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Chemical Structure| 19227-11-3 Chemical Structure| 19227-11-3

Structure of 19227-11-3

Chemical Structure| 19227-11-3

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Product Details of [ 19227-11-3 ]

CAS No. :19227-11-3
Formula : C8H10N2O
M.W : 150.18
SMILES Code : N=C(NO)CC1=CC=CC=C1
MDL No. :MFCD05864463
Boiling Point : No data available
InChI Key :FVYBAJYRRIYNBN-UHFFFAOYSA-N
Pubchem ID :9566465

Safety of [ 19227-11-3 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335-H302+H312+H332
Precautionary Statements:P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501

Application In Synthesis of [ 19227-11-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 19227-11-3 ]

[ 19227-11-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 1072-84-0 ]
  • [ 19227-11-3 ]
  • [ 1023731-18-1 ]
  • 2
  • [ 161601-29-2 ]
  • [ 19227-11-3 ]
  • tert-butyl {(1S,3S)-3-[([(1Z)-1-amino-2-phenylethylidene]amino}oxy)carbonyl]cyclopentyl}carbamate [ No CAS ]
YieldReaction ConditionsOperation in experiment
StepB; iert-butyl {(lS;3^3-[([(lZ>l-amino-2-phenylethylidene]amino}oxy)carbonyl]cyclopentyl} carbamate; To a solution of (lS,3£)-3-[(fcr/-butoxycarbonyl)amino]cyclopentanecarboxylic acid (1.99 g, 8.68 mmol) in methylene chloride (20 mL) at room temperature was added HOBt (1.40 g, 9.11 mmol), and EDC (1.83 g, 9.55 mmol). After 40 minutes, (lZ)-./V'-hydroxy-2-phenylethanimidamide (1.70 g, 11.3 mmol) was added to the reaction. After 8 hours, the reaction was poured into saturated sodium bicarbonate solution and extracted with methylene chloride. The combined organic layers were washed with 1M sodium hydroxide, dried over sodium sulfate, filtered and concentrated to give the title compound (3.97 g) as a waxy solid. MS 362 (M+l).
 

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