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Chemical Structure| 186376-18-1 Chemical Structure| 186376-18-1

Structure of 186376-18-1

Chemical Structure| 186376-18-1

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Product Details of [ 186376-18-1 ]

CAS No. :186376-18-1
Formula : C17H24N2O2
M.W : 288.39
SMILES Code : CC(C)(C)OC(=O)NC1C2CN(CC3=CC=CC=C3)CC12
MDL No. :MFCD08694882

Safety of [ 186376-18-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 186376-18-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 186376-18-1 ]

[ 186376-18-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 186376-18-1 ]
  • [ 198211-38-0 ]
YieldReaction ConditionsOperation in experiment
To a solution of the compound obtained from step a above (1Og, 34.72 mmole) in methanol (150 ml), was added palladium on carbon (10%, 7 g) and the reaction mixture was refluxed for 30 minutes. To it was added ammonium formate (10.94 g, 173.61 mmol) slowly over a period of 15 minutes and stirred for 15 minutes at 700C. Filtered the reaction mixture through a prewashed celite pad. The organic solvent was evaporated under reduced pressure, added a saturated solution of sodium bicarbonate, extracted with ethyl acetate, washed with water and dried over anhydrous sodium sulphate. The organic layer was concentrated under reduced pressure to furnish the title compound. Yield = 4.3 g.
 

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