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Chemical Structure| 183594-86-7 Chemical Structure| 183594-86-7

Structure of 183594-86-7

Chemical Structure| 183594-86-7

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Product Details of [ 183594-86-7 ]

CAS No. :183594-86-7
Formula : C18H22N4
M.W : 294.39
SMILES Code : CN(C)/C=C/C1=CC(C2=NC=CC(/C=C/N(C)C)=C2)=NC=C1
MDL No. :MFCD02667596

Safety of [ 183594-86-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P302+P352-P305+P351+P338

Application In Synthesis of [ 183594-86-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 183594-86-7 ]

[ 183594-86-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 183594-86-7 ]
  • [ 99970-84-0 ]
YieldReaction ConditionsOperation in experiment
78% With sodium periodate; In tetrahydrofuran; water; at 50℃; for 20h;Inert atmosphere; The synthesis of 2 was previously published but, in this study, another synthetic route was employed. 1 (1.00 g, 3.40 mmol, 1.0 equiv.) was dissolved in 100 mL THF under N2 atmosphere. Dropwise, a solution of NaIO4 (7.27 g, 33.97 mmol, 10.0 equiv.) in H2O (100 mL) was added. The mixture was heated to 50 C for 20 h. During this time, the formation of a white suspension was observed. After this time, the solution was cooled down to room temperature and the solvent removed. The residue was dissolved in DCM and washed with H2O. The organic phase was dried over MgSO4, filtered and the solvent was removed by rotary evaporation. The product was dissolved in DCM and isolated by precipitation from pentane. The solid was obtained by filtration as apale yellow solid. Yield: 78%. Experimental data fits with the literature.
 

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