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Chemical Structure| 180741-37-1 Chemical Structure| 180741-37-1

Structure of 180741-37-1

Chemical Structure| 180741-37-1

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Product Details of [ 180741-37-1 ]

CAS No. :180741-37-1
Formula : C6H10N2O
M.W : 126.16
SMILES Code : OCCCN1N=CC=C1
MDL No. :MFCD03727229
InChI Key :PMKIEDXXIYUBKC-UHFFFAOYSA-N
Pubchem ID :17608730

Safety of [ 180741-37-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 180741-37-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 180741-37-1 ]

[ 180741-37-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1298031-94-3 ]
  • [ 180741-37-1 ]
  • 6-chloro-2-methyl-8-(3-pyrazol-1-ylpropoxy)imidazo[1,2-b]pyridazine [ No CAS ]
YieldReaction ConditionsOperation in experiment
48% With caesium carbonate; In acetonitrile; at 40℃; for 16h; 8-Bromo-6-chloro-2-methyl-imidazo[l,2-b]pyridazine (124 mg, 0.50 mmol) was combined with 3-(lH-pyrazol-l-yl)propan- l-ol (252 mg, 2.0 mmol) and cesium carbonate (650 mg, 2.0 mmol) in CH3CN (4 mL). The mixture was stirred at 40 C for 16 h. To the mixture was added EtOAc (10 mL). The mixture was filtered over Celite. The filtrate was concentrated. The residue was chromatographed on silica gel, eluting with 0- 10% MeOH in EtOAc to yield 6- chloro-2-methyl-8-(3-pyrazol- l-ylpropoxy)imidazo[l,2-b]pyridazine (70 mg, 48%). MS m/z 292.3 [M+H]+.
 

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