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Chemical Structure| 179534-78-2 Chemical Structure| 179534-78-2

Structure of 179534-78-2

Chemical Structure| 179534-78-2

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Product Details of [ 179534-78-2 ]

CAS No. :179534-78-2
Formula : C12H13F3N2O
M.W : 258.24
SMILES Code : O=C(N1CCNCC1)C2=CC=CC=C2C(F)(F)F
MDL No. :MFCD08442668

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Application In Synthesis of [ 179534-78-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 179534-78-2 ]

[ 179534-78-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 179534-78-2 ]
  • [ 65202-50-8 ]
  • [ 840488-99-5 ]
YieldReaction ConditionsOperation in experiment
With potassium carbonate; In 1,4-dioxane; for 71h;Heating / reflux; Step 5; Methyl 6-(4-[2-(trifluoromethyl)benzoyl]piperazin-l-yUpyrida2ine-3-carboxylate; To a mixture of methyl -chloropyridazine-S-carboxylate (3.9 g, 22.6 mmol), l-[2- (trifluoromethyl)benzoyl]piperazine (7.0 g, 27.1 mmol) and potassium carbonate (6.5 g, 47 mmol) was added 100 mL of dioxane and the mixture was heated to reflux for 71 h. The mixture was cooled to room temperature and the solid filtered and swirled in 4: 1 ethepiethyl acetate at reflux for 45 min. The solid was filtered to provide the title compound.
 

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