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Chemical Structure| 174398-83-5 Chemical Structure| 174398-83-5

Structure of 174398-83-5

Chemical Structure| 174398-83-5

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Product Details of [ 174398-83-5 ]

CAS No. :174398-83-5
Formula : C23H22O4
M.W : 362.42
SMILES Code : O=C(OCC)C1=CC=C(OCC2=CC=CC=C2)C(OCC3=CC=CC=C3)=C1
MDL No. :MFCD01861873
InChI Key :OYGDJCJJPUKBCI-UHFFFAOYSA-N
Pubchem ID :11325933

Safety of [ 174398-83-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 174398-83-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 174398-83-5 ]

[ 174398-83-5 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 3943-89-3 ]
  • [ 100-39-0 ]
  • [ 188564-63-8 ]
  • [ 177429-27-5 ]
  • [ 174398-83-5 ]
  • 2
  • [ 174398-83-5 ]
  • [ 1570-05-4 ]
YieldReaction ConditionsOperation in experiment
With water; sodium hydroxide; In ethanol; at 60℃; for 2h; (Second step) Stirrer,And a reaction vessel equipped with a thermometer,20 g (55 mmol) of the compound represented by formula (S-1),Sodium hydroxide 5.3 g (132 mmol), ethanol 200 ml,Add 50 ml of pure water,Hydrolysis was performed by stirring at 60 C. for 2 hours.After the reaction is completeA 10% aqueous hydrochloric acid solution was added to neutralize the reaction solution.After cooling the reaction solution, the precipitated crystals are filtered,The crystals were washed with water and ethanol and dried.Further, 18 g (53 mmol) of 3,4-dibenzyloxybenzoic acid obtained was added to a stirrer,Charge into a reaction vessel equipped with a cooler and thermometer,Furthermore, 3.7 g (27 mmol) of 2- (4-hydroxyphenyl) ethanol,610 mg of dimethylaminopyridine,200 ml of methylene chloride was charged.Keep the reaction vessel at 5 C or below with an ice-cooled bath.In an atmosphere of nitrogen gas, 8 g (63 mmol) of diisopropylcarbodiimide was slowly added dropwise. After completion of dropping, the reaction vessel was returned to room temperature and reacted for 5 hours. After the reaction solution was filtered, 200 ml of methylene chloride was added to the filtrate, washed with a 10% aqueous hydrochloric acid solution, further washed with saturated brine, and the organic layer was dried over anhydrous sodium sulfate. After the solvent was distilled off, the residue was purified with a double amount (weight ratio) silica gel column and recrystallized with methylene chloride / methanol to obtain 17.7 g of a compound represented by the formula (S-3).
 

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