Home Cart Sign in  
Chemical Structure| 17357-32-3 Chemical Structure| 17357-32-3

Structure of 17357-32-3

Chemical Structure| 17357-32-3

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 17357-32-3 ]

CAS No. :17357-32-3
Formula : C6H4Br2O2
M.W : 267.90
SMILES Code : BrC1=CC=C(C(CBr)=O)O1

Safety of [ 17357-32-3 ]

Application In Synthesis of [ 17357-32-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 17357-32-3 ]

[ 17357-32-3 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 3199-50-6 ]
  • [ 17357-32-3 ]
YieldReaction ConditionsOperation in experiment
65% With bromine; In 1,4-dioxane; diethyl ether; at 0 - 5℃; for 1h; To a solution of 1-(5-Bromofuran-2-yl)-ethanone (1.88 g, 10 mmol) in 12 mL dioxane/ether (1:2) with cooling at 0-5 C. and stirring was portionwise added bromine (0.52 mL, 10 mmol) over 1 h. The reaction mixture was further stirred with cooling. After TLC indicated complete bromination, the reaction mixture was diluted with ether (50 mL) and water (100 mL). The ethereal layer was separated, washed with 1 M aqueous sodium bicarbonate solution, and dried over Na2SO4. The ether extract was distilled to afford 2 in 65% yield, mp 96-97 C. (hexanes/ether, Lit. mp 98.5-99.5 C.; see Brown E., Iowa State Coll. J. Sci., 11, 221-225 (1937)). 1H NMR (CDCl3); delta 4.24 (s, 2H), 6.55 (d, J=3.6 Hz, 1H), 7.27 (d, J=3.6 Hz, 1H). 13C NMR; delta 179.0, 151.9, 129.4, 121.1, 115.0, 29.5.
  • 2
  • [ 17357-32-3 ]
  • [ 151169-74-3 ]
  • [ 657405-39-5 ]
YieldReaction ConditionsOperation in experiment
62% Example lb) (536mg, [2MMOL)] and Pd (PPh3) 4 (120mg, [0.] [LOMMOL)] in DME [(25ML)] were stirred at room temperature for [10MIN.] 2,3-Dichlorobenzene boronic acid [(L.] [OG,] 5.24mmol) was then added and the mixture heated to [80C] for 3h and for a further 18h at room temperature. The reaction was diluted with water [(50ML)] and ethyl acetate [(100ML),] the aqueous layer separated and washed with ethyl acetate [(50ML] x 2). The combined organics were washed with brine, dried [(MGS04)] and evaporated to give the title compound as a dark orange gum. The product was purified by flash chromatography (10% EtOAc/isohexane) to give a pale yellow solid (315mg, [62%).'H] NMR [(CDC13)] 8 2.56 (3H, s, CH3), 7.27- 7.33 (3H, [M,] ArH), 7.52 [(1H,] d, [ARH),] 7.90 [(1H,] d, ArH).
 

Historical Records

Technical Information

Categories