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Chemical Structure| 16582-93-7 Chemical Structure| 16582-93-7

Structure of 16582-93-7

Chemical Structure| 16582-93-7

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Product Details of [ 16582-93-7 ]

CAS No. :16582-93-7
Formula : C7HF4N
M.W : 175.08
SMILES Code : N#CC1=CC(F)=C(F)C(F)=C1F
MDL No. :MFCD00040187
InChI Key :GLTGXIGJLCSEAM-UHFFFAOYSA-N
Pubchem ID :600224

Safety of [ 16582-93-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H301+H311+H331-H315-H319-H227
Precautionary Statements:P501-P261-P270-P210-P271-P264-P280-P370+P378-P337+P313-P305+P351+P338-P361+P364-P332+P313-P301+P310+P330-P302+P352+P312-P304+P340+P311-P403+P233-P403+P235-P405
Class:6.1
UN#:3276
Packing Group:

Application In Synthesis of [ 16582-93-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 16582-93-7 ]

[ 16582-93-7 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 827-08-7 ]
  • [ 16582-93-7 ]
  • 3
  • [ 1255308-97-4 ]
  • [ 16582-93-7 ]
  • C79H41N5S4 [ No CAS ]
YieldReaction ConditionsOperation in experiment
81.1% With caesium carbonate; In N,N-dimethyl-formamide; at 150℃; for 12h;Inert atmosphere; Schlenk technique; In a 100mL Schlenk bottle,Add 0.50 g (2.86 mmol) of 2,3,4,5-tetrafluorobenzonitrile, 3.51 g (12.85 mmol) of <strong>[1255308-97-4]5H-[1]benzothieno[3,2-c]carbazole</strong>, and 4.65 g of cesium carbonate ( 14.28mmol),N,N-dimethylformamide 60mL,The reaction was stirred under reflux for 12 hours under argon atmosphere, and the reaction was completed.After cooling to room temperature, poured into water and a yellow solid precipitated.The crude product was obtained by suction filtration.The crude product obtained by suction filtration was separated by column chromatography (silica gel was 350 mesh,The eluent is petroleum ether: dichloromethane = 2:1 (V/V), and the solvent is distilled off.After drying, 2.75 g of a yellow solid was obtained in a yield of 81.1%.
  • 4
  • [ 1255308-97-4 ]
  • [ 16582-93-7 ]
  • C61H30F2N4S3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
73.9% With caesium carbonate; In N,N-dimethyl-formamide; at 150℃; for 12h;Inert atmosphere; Schlenk technique; In a 100mL Schlenk bottle,Add 2,3,4,5,6-pentafluorobenzonitrile 1.00g (5.18mmol)<strong>[1255308-97-4]5H-[1]benzothieno[3,2-c]carbazole</strong> 4.25 g (15.54 mmol),5.91 g (18.13 mmol) of cesium carbonate and 60 mL of N,N-dimethylformamide.The reaction was stirred under reflux for 12 hours under argon atmosphere, and the reaction was completed.After cooling to room temperature, it was poured into water, a yellow solid was precipitated, and filtered to give a crude product.The crude product obtained by suction filtration was separated by column chromatography (silica gel was 350 mesh,The eluent is petroleum ether: dichloromethane = 2:1 (V/V), and the solvent is distilled off.After drying, 3.65 g of a yellow solid was obtained in a yield of 73.9%.
 

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