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Chemical Structure| 16566-20-4 Chemical Structure| 16566-20-4

Structure of 16566-20-4

Chemical Structure| 16566-20-4

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Product Details of [ 16566-20-4 ]

CAS No. :16566-20-4
Formula : C8H7N3
M.W : 145.16
SMILES Code : NC1=CC=CC2=C1N=CC=N2
MDL No. :MFCD09743743

Safety of [ 16566-20-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P261-P280-P305+P351+P338

Application In Synthesis of [ 16566-20-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 16566-20-4 ]
  • Downstream synthetic route of [ 16566-20-4 ]

[ 16566-20-4 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 16566-20-4 ]
  • [ 76982-23-5 ]
YieldReaction ConditionsOperation in experiment
14 g
Stage #1: With hydrogenchloride In water at 0℃; for 0.5 h;
Stage #2: With copper(I) bromide In water at 20℃; for 6 h;
Add 17 g of 5-aminobenzopyrazine to 50 ml of water, cool to 0°C, add 25 ml of concentrated hydrochloric acid, stir for 0.5 hour, add 10 g of copper bromide in portions, stir at room temperature for 6 hours, add water, extract and separate , Drying, concentration, the residue was separated on a silica gel column to obtain 14g 5-bromobenzopyrazine
References: [1] Patent: CN107793370, 2018, A, . Location in patent: Paragraph 0023; 0024.
 

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