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Chemical Structure| 1613639-46-5 Chemical Structure| 1613639-46-5

Structure of 1613639-46-5

Chemical Structure| 1613639-46-5

3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole

CAS No.: 1613639-46-5

4.5 *For Research Use Only !

Cat. No.: A475378 Purity: 98%

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Product Details of [ 1613639-46-5 ]

CAS No. :1613639-46-5
Formula : C13H16BFN2O2
M.W : 262.09
SMILES Code : CC1(C)C(C)(C)OB(C2=CC3=C(NN=C3F)C=C2)O1
MDL No. :MFCD30145551

Safety of [ 1613639-46-5 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 1613639-46-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1613639-46-5 ]

[ 1613639-46-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1211537-09-5 ]
  • [ 73183-34-3 ]
  • [ 1613639-46-5 ]
YieldReaction ConditionsOperation in experiment
280 mg With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 95℃;Inert atmosphere; Under an Ar atmosphere, a mixture of 5-bromo-3-fluoro-lH-indazole (250 mg, 1.168 mmol), bis(pinacolato)diboron (593 mg, 2.336 mmol), [l , l-bis(diphenylphosphino)ferrocene] dichloropalladium(II) (95 mg, 0.1 17 mmol) and AcOK (229 mg, 2.336 mmol) in 1 ,4-dioxane was heated at 95 C overnight. After cooling down to the room temperature, the mixture was concentrated and the residue was purified by flash column to give 3-fluoro-5-(4,4,5,5- tetramethyl-[l ,3,2]dioxaborolan-2-yl)-lH-indazole (280 mg) as a white solid
 

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