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Chemical Structure| 1572414-83-5 Chemical Structure| 1572414-83-5
Chemical Structure| 1572414-83-5

ML-323

CAS No.: 1572414-83-5

ML323 exhibits reversible inhibition of USP1-UAF1 with IC50 of 76 nM and it does not inhibit deneddylase and deSUMOylase.

4.5 *For Research Use Only !

Cat. No.: A160586 Purity: 98%

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Product Details of ML-323

CAS No. :1572414-83-5
Formula : C23H24N6
M.W : 384.48
SMILES Code : CC(C1=CC=CC=C1C2=NC=C(C)C(NCC3=CC=C(N4N=NC=C4)C=C3)=N2)C
MDL No. :MFCD28099817
InChI Key :VUIRVWPJNKZOSS-UHFFFAOYSA-N
Pubchem ID :60167849

Safety of ML-323

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Isoform Comparison

Biological Activity

Target
  • DUB

    USP1-UAF1, IC50:76 nM

Protocol

Bio Calculators
Preparing Stock Solutions 1mg 5mg 10mg

1 mM

5 mM

10 mM

2.60mL

0.52mL

0.26mL

13.00mL

2.60mL

1.30mL

26.01mL

5.20mL

2.60mL

Dissolving Methods
Please choose the appropriate dissolution scheme according to your animal administration guide.For the following dissolution schemes, clear stock solution should be prepared according to in vitro experiments, and then cosolvent should be added in turn:

in order to ensure the reliability of the experimental results, the clarified stock solution can be properly preserved according to the storage conditions; The working fluid for in vivo experiment is recommended to be prepared now and used on the same day;

The percentage shown in front of the following solvent refers to the volume ratio of the solvent in the final solution; If precipitation or precipitation occurs in the preparation process, it can be assisted by heating and/or ultrasound.
Protocol 1
Protocol 2

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