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Structure of 152628-01-8

Chemical Structure| 152628-01-8

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Product Details of [ 152628-01-8 ]

CAS No. :152628-01-8
Formula : C13H16N2O5
M.W : 280.28
SMILES Code : O=C(OC)C1=CC([N+]([O-])=O)=C(NC(CCC)=O)C(C)=C1
MDL No. :MFCD08062447
InChI Key :IGCBUUTXGYCQAI-UHFFFAOYSA-N
Pubchem ID :9795680

Safety of [ 152628-01-8 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 152628-01-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 152628-01-8 ]

[ 152628-01-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 152628-01-8 ]
  • [ 152628-03-0 ]
YieldReaction ConditionsOperation in experiment
96.4% With sodium dithionite; water; at 70 - 100℃; Example 4:4-butyramido-3-methyl-5-nitro methyl benzoate (II) (10 gm, 0.036 moles), was suspended in water (60 ml) and heated to 70-80 C. A suspension of sodium dithionite (21.75 gm, 0.124 moles) in water (60 ml) was added gradually to the above mass and the temperature is raised to 90-100 C. After the reaction complies, the pH of the reaction mixture was adjusted to 10-11 and continued to stir at same temperature until the methyl-4-methyl-2-propyl-lH-benzimidazole-6-carboxylate disappears in TLC. Then the pH of the reaction mass adjusted to pH 6-6.5. The solid obtained was filtered and dried at 45-50 C to afford 2-n-propyl-4-methyl-6- carboxy benzimidazole (7.5 gms, Yield: 96.4 %).
 

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