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Chemical Structure| 149506-86-5 Chemical Structure| 149506-86-5

Structure of 149506-86-5

Chemical Structure| 149506-86-5

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Product Details of [ 149506-86-5 ]

CAS No. :149506-86-5
Formula : C13H8ClNO2S
M.W : 277.73
SMILES Code : O=S(C1=CC=C(C2=CC=C(C#N)C=C2)C=C1)(Cl)=O
MDL No. :MFCD20040108

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Application In Synthesis of [ 149506-86-5 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 149506-86-5 ]

[ 149506-86-5 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 149506-86-5 ]
  • [ 145901-11-7 ]
  • 4'-cyano-N-(1H-pyrrolo[2,3-b]pyridin-6-yl)[1,1'-biphenyl]-4-sulfonamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
67.8% With pyridine; at 20℃; In pyridine (10 ml) 4'-cyano-[1,1'-biphenyl]-4-sulfonyl chloride(70 mg, 0.5 mmol) was dissolved in a solution <strong>[145901-11-7]1H-pyrrolo[2,3-b]pyridin-6-amine</strong>(140 mg, 0.5 mmol) to It was added and stirred for 4 hours at room temperature. Check the completion of the reaction, whether by TLC, and the residue was purified by silica gel chromatography by concentration of the above reaction mixture: Purification of (ethyl acetate petroleum ether = 1: 2) to give the title compound as a white solid (67.8 mg, 67.8% yield).
 

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