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Chemical Structure| 1467059-89-7 Chemical Structure| 1467059-89-7

Structure of 1467059-89-7

Chemical Structure| 1467059-89-7

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Product Details of [ 1467059-89-7 ]

CAS No. :1467059-89-7
Formula : C15H21BO3
M.W : 260.14
SMILES Code : OC1(C2=CC=C(B3OCC(C)(C)CO3)C=C2)CCC1
MDL No. :MFCD28133714

Safety of [ 1467059-89-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1467059-89-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1467059-89-7 ]

[ 1467059-89-7 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 19936-14-2 ]
  • [ 201733-56-4 ]
  • [ 1467059-89-7 ]
YieldReaction ConditionsOperation in experiment
76% With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate; In 1,4-dioxane; at 110℃; for 2h;Inert atmosphere; A mixture of 5,5,5',5'-tetramethyl-2,2'-bi(1,3,2-dioxaborinane) (16.50 g, 48.33 mmol), oven dried potassium acetate (20.03 g, 204.1 mmol), and <strong>[19936-14-2]1-(4-bromophenyl)cyclobutanol</strong> (10.00 g, 44.03 mmol) in 1,4-dioxane (120 mL) was degassed with N2 for 15 min, then treated with [1,1'-bis(diphenylphosphino)ferrocene]dichloropalladium(II) (2.44 g, 2.99 mmol). The reaction mixture was heated to 110 C. and stirred for 2 hours under N2. The reaction mixture was cooled to room temperature and filtered through celite, eluting with EtOAc. The filtrate was evaporated to give a black oil, which was purified by flash chromatography (0-50% EtOAc/Heptane) three times to afford the title compound (8.68 g, 76%) as a white solid. GC/MS: 259. 1H NMR (400 MHz, CD3Cl) delta 7.83 (d, J=8.05 Hz, 2H), 7.50 (d, J=8.29 Hz, 2H), 3.78 (s, 4H), 2.65-2.52 (m, 2H), 2.38-2.42 (m, 2H), 1.98-2.03 (m, 1H), 1.72-1.80 (m, 1H), 1.03 (s, 6H).
  • 2
  • [ 1467059-89-7 ]
  • [ 1467057-23-3 ]
  • 3
  • [ 1467059-89-7 ]
  • [ 1467059-91-1 ]
  • [ 1467057-23-3 ]
  • 4
  • [ 1467059-87-5 ]
  • [ 1467059-89-7 ]
  • [ 1467057-23-3 ]
 

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