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Chemical Structure| 14510-07-7 Chemical Structure| 14510-07-7

Structure of 14510-07-7

Chemical Structure| 14510-07-7

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Product Details of [ 14510-07-7 ]

CAS No. :14510-07-7
Formula : C10H7NO2
M.W : 173.17
SMILES Code : O=CC1=CC=NC2=C(O)C=CC=C12
MDL No. :MFCD06824353
InChI Key :PYOVEJVKZRJJQK-UHFFFAOYSA-N
Pubchem ID :12901558

Safety of [ 14510-07-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H332
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P330-P363-P501

Application In Synthesis of [ 14510-07-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 14510-07-7 ]

[ 14510-07-7 ] Synthesis Path-Downstream   1~2

  • 2
  • [ 14510-07-7 ]
  • [ 13361-34-7 ]
  • C21H24N2O3 [ No CAS ]
YieldReaction ConditionsOperation in experiment
83.1% With cadmium(II) iodide; at 75℃; for 1h; 4-carbaldehyde-8-hydroxyquinoline (1.16 g, 6.70 mmol), 2-ethylhexyl cyanoacetate (1.5 ml, 6.70 mmol) and cadmium iodide (0.25 g, 0.67 mmol) were put into a 25 ml round flaskand thoroughly mixed and heated at 75 C for 1 hour. After cooled to room temperature, the mixture was washed with 1% aqueous alcohol and extracted with CH2Cl2, dried with anhydrous MgSO4 and then the solvent was removed on a rotary evaporator. The crude product was purification using column chromatography (silica gel) with the mixture of dichloromethane (CH2Cl2) and n-hexane (2:3, v/v) as the eluent to give a yellow solid (1.96 g, yield 83.1%). δH (400 MHz; (CD3)2SO; Me4Si): 10.19 (s, 1H), 9.03 (d, 1H, J=4 Hz), 9.00 (s, 1H), 7.94 (d, 1H, J=4 Hz), 7.58 (t, 1H, J=8 Hz), 7.44 (d, 1H, J=8 Hz), 7.22 (d, 1H, J=8 Hz), 4.26 (m, 2H), 1.71 (m, 1H), 1.27-1.45 (m, 8H), 0.87-0.94 (m, 6H). δC (600 MHz; (CD3)2CO; Me4Si): 161.8, 154.5, 151.6, 148.7, 139.6, 138.4, 130.2, 126.8, 122.0, 114.8, 114.4, 112.1, 112.0, 69.7, 39.7, 31.1, 29.7, 24.5, 23.6, 14.3, 11.4. MS (MALDI-TOF): Calcd for C21H24N2O3 (M+1): 352.43, Found: 352.39.
 

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• Appel Reaction • Barbier Coupling Reaction • Baylis-Hillman Reaction • Bucherer-Bergs Reaction • Buchwald-Hartwig C-N Bond and C-O Bond Formation Reactions • Chugaev Reaction • Clemmensen Reduction • Complex Metal Hydride Reductions • Corey-Chaykovsky Reaction • Corey-Fuchs Reaction • Corey-Kim Oxidation • Dess-Martin Oxidation • Fischer Indole Synthesis • Grignard Reaction • Hantzsch Dihydropyridine Synthesis • Henry Nitroaldol Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Jones Oxidation • Julia-Kocienski Olefination • Knoevenagel Condensation • Leuckart-Wallach Reaction • Martin's Sulfurane Dehydrating Reagent • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Mitsunobu Reaction • Moffatt Oxidation • Mukaiyama Aldol Reaction • Nozaki-Hiyama-Kishi Reaction • Oxidation of Alcohols by DMSO • Passerini Reaction • Paternò-Büchi Reaction • Petasis Reaction • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Alcohols • Preparation of Aldehydes and Ketones • Preparation of Amines • Prins Reaction • Reactions of Alcohols • Reactions of Aldehydes and Ketones • Reactions of Amines • Reactions with Organometallic Reagents • Reformatsky Reaction • Ritter Reaction • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Sharpless Olefin Synthesis • Stetter Reaction • Stobbe Condensation • Swern Oxidation • Tebbe Olefination • Ugi Reaction • Wittig Reaction • Wolff-Kishner Reduction

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