Home Cart Sign in  
Chemical Structure| 1450711-53-1 Chemical Structure| 1450711-53-1

Structure of 1450711-53-1

Chemical Structure| 1450711-53-1

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1450711-53-1 ]

CAS No. :1450711-53-1
Formula : C7H8BBrO2
M.W : 214.85
SMILES Code : OB(C1=CC(C)=CC=C1Br)O
MDL No. :MFCD26045274
InChI Key :NVMZSLAJUCDXCS-UHFFFAOYSA-N
Pubchem ID :58531767

Safety of [ 1450711-53-1 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319-H335
Precautionary Statements:P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 1450711-53-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1450711-53-1 ]

[ 1450711-53-1 ] Synthesis Path-Downstream   1~12

  • 1
  • [ 1008106-91-9 ]
  • [ 74-88-4 ]
  • [ 1450711-53-1 ]
  • [ 774608-13-8 ]
  • 2
  • [ 1450711-53-1 ]
  • C8H6Br2I2O2 [ No CAS ]
  • C22H18Br4O2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
58% With potassium phosphate; tetrakis(triphenylphosphine) palladium(0); In tetrahydrofuran; water; at 80.0℃; for 20.0h;Inert atmosphere; Under a nitrogen atmosphere, a 500 ml three-necked flask was charged with 1,3-dibromo-4,6-diiodo-2,5-dimethoxy (54.77 g, 0.1 mol, 1 equivalent), 2-bromo-5 -Methylphenylboronic acid (64.20 g, 0.3 mol, 3 eq), tetrakis (triphenylphosphine) palladium (5.8 g, 0.005 mol, 0.05 eq), potassium phosphate (55.16 g, 0.4 mol, 4 eq), THF ( 150 ml), water (40 ml), and the reaction was heated to 80 degrees Celsius and stirred for 20 hours. After the reaction was completed, the solvent was spin-dried, and the crude product was purified by chromatography (ethyl acetate / hexane = 1/15) to obtain intermediate 1- (3-1) (36.76 g, yield 58%).
  • 3
  • [ 1450711-53-1 ]
  • C52H36N2P2 [ No CAS ]
  • 4
  • [ 1450711-53-1 ]
  • C47H31F3N2O3P2S [ No CAS ]
  • 5
  • [ 1450711-53-1 ]
  • C34H22F6O6P2S2 [ No CAS ]
  • 6
  • [ 1450711-53-1 ]
  • C34H28O2P2 [ No CAS ]
  • 7
  • [ 1450711-53-1 ]
  • C52H36N2O2P2 [ No CAS ]
  • 8
  • [ 1450711-53-1 ]
  • C24H14BrNO2 [ No CAS ]
  • C31H20BrNO2 [ No CAS ]
YieldReaction ConditionsOperation in experiment
With bis-triphenylphosphine-palladium(II) chloride; potassium carbonate; triphenylphosphine; In ethanol; water; toluene; for 24.0h;Inert atmosphere; Reflux; In a nitrogen atmosphere, add 0.01mol intermediate H-19, 0.011mol reactant Y-19, 0.03mol potassium carbonate, 1×10-4mol Pd(PPh3)Cl2 and 1×10-4mol triphenyl phosphineto a 200mL three-necked flask , then add 120mL of a mixed solution of V toluene: V ethanol: V water = 1:1:1, heat to reflux for 24 hours, observe the reaction by TLC, until the reaction is complete, cool to room temperature naturally, filter, and spin-evaporate the filtrate to No fractions. The obtained substance was purified by a silica gel column (V dichloromethane: V petroleum ether = 1:5 mixed solvent as eluent) to obtain Intermediate X-19.
  • 9
  • [ 1450711-53-1 ]
  • [ 170456-80-1 ]
  • C22H18BrNO2S [ No CAS ]
  • 10
  • [ 19658-77-6 ]
  • [ 1450711-53-1 ]
  • 1-(2-bromo-5-methylphenyl)isoquinoline [ No CAS ]
  • 11
  • [ 26218-78-0 ]
  • [ 1450711-53-1 ]
  • methyl 6-(2-bromo-5-methylphenyl)nicotinate [ No CAS ]
  • 12
  • [ 26218-78-0 ]
  • [ 1450711-53-1 ]
  • methyl 2,3,6-trimethyl-1'H-spiro[indene-1,2'-pyridine]-5'-carboxylate [ No CAS ]
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 1450711-53-1 ]

Organoborons

Chemical Structure| 854636-01-4

A565068 [854636-01-4]

(2-Bromo-4-methylphenyl)boronic acid

Similarity: 0.95

Chemical Structure| 244205-40-1

A159659 [244205-40-1]

(2-Bromophenyl)boronic acid

Similarity: 0.86

Chemical Structure| 849062-36-8

A621328 [849062-36-8]

(3-Bromo-5-methylphenyl)boronic acid

Similarity: 0.85

Chemical Structure| 851756-50-8

A256202 [851756-50-8]

(2,6-Dibromophenyl)boronic acid

Similarity: 0.84

Chemical Structure| 1008106-93-1

A154115 [1008106-93-1]

2,5-Dibromophenylboronic acid

Similarity: 0.84

Aryls

Chemical Structure| 854636-01-4

A565068 [854636-01-4]

(2-Bromo-4-methylphenyl)boronic acid

Similarity: 0.95

Chemical Structure| 244205-40-1

A159659 [244205-40-1]

(2-Bromophenyl)boronic acid

Similarity: 0.86

Chemical Structure| 849062-36-8

A621328 [849062-36-8]

(3-Bromo-5-methylphenyl)boronic acid

Similarity: 0.85

Chemical Structure| 851756-50-8

A256202 [851756-50-8]

(2,6-Dibromophenyl)boronic acid

Similarity: 0.84

Chemical Structure| 1008106-93-1

A154115 [1008106-93-1]

2,5-Dibromophenylboronic acid

Similarity: 0.84

Bromides

Chemical Structure| 854636-01-4

A565068 [854636-01-4]

(2-Bromo-4-methylphenyl)boronic acid

Similarity: 0.95

Chemical Structure| 244205-40-1

A159659 [244205-40-1]

(2-Bromophenyl)boronic acid

Similarity: 0.86

Chemical Structure| 849062-36-8

A621328 [849062-36-8]

(3-Bromo-5-methylphenyl)boronic acid

Similarity: 0.85

Chemical Structure| 851756-50-8

A256202 [851756-50-8]

(2,6-Dibromophenyl)boronic acid

Similarity: 0.84

Chemical Structure| 1008106-93-1

A154115 [1008106-93-1]

2,5-Dibromophenylboronic acid

Similarity: 0.84