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Chemical Structure| 14386-64-2 Chemical Structure| 14386-64-2

Structure of 14386-64-2

Chemical Structure| 14386-64-2

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Product Details of [ 14386-64-2 ]

CAS No. :14386-64-2
Formula : C16H23BrO2
M.W : 327.26
SMILES Code : O=C(C1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1)CBr
MDL No. :MFCD00173889
InChI Key :UYPXQSLSPUBZQW-UHFFFAOYSA-N
Pubchem ID :616161

Safety of [ 14386-64-2 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314-H290
Precautionary Statements:P501-P260-P234-P264-P280-P390-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P406-P405
Class:8
UN#:3261
Packing Group:

Application In Synthesis of [ 14386-64-2 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 14386-64-2 ]

[ 14386-64-2 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 214834-18-1 ]
  • [ 14386-64-2 ]
  • C27H40N2O3S [ No CAS ]
YieldReaction ConditionsOperation in experiment
The bromoketone (1.3 g, 4.0 mmol) was dissolved in 1:1 ethyl alcohol/THF (20 mL), the thioamide (SeeExample 1 Step 9 (0.97 g, 4.0 mmol) added, and the mixture stirred at room temperature overnight. The volatiles were removed in. vac. and the residue dissolved in DMF (6 mL). Et3N (0.48 g, 4.8 mmol) and di-Λ»rr-butyl dicarbonate (0.26 g, 1.2 mmol) were added and the solution stirred at RT for 1 hour. The mixture was diluted with water, followed by aqueous/EtOAc work-up and silica gel chromatography (EtOAc : hexanes (1 :9)) to afford the titled compound.
 

Historical Records

Technical Information

• Acidity of Phenols • Alkyl Halide Occurrence • Baeyer-Villiger Oxidation • Barbier Coupling Reaction • Baylis-Hillman Reaction • Benzylic Oxidation • Birch Reduction • Blanc Chloromethylation • Bucherer-Bergs Reaction • Chan-Lam Coupling Reaction • Clemmensen Reduction • Corey-Bakshi-Shibata (CBS) Reduction • Corey-Chaykovsky Reaction • Electrophilic Substitution of the Phenol Aromatic Ring • Etherification Reaction of Phenolic Hydroxyl Group • Fischer Indole Synthesis • Friedel-Crafts Reaction • General Reactivity • Grignard Reaction • Halogenation of Phenols • Henry Nitroaldol Reaction • Hiyama Cross-Coupling Reaction • Horner-Wadsworth-Emmons Reaction • Hydride Reductions • Hydrogenolysis of Benzyl Ether • Kinetics of Alkyl Halides • Kumada Cross-Coupling Reaction • Lawesson's Reagent • Leuckart-Wallach Reaction • McMurry Coupling • Meerwein-Ponndorf-Verley Reduction • Oxidation of Phenols • Passerini Reaction • Paternò-Büchi Reaction • Pechmann Coumarin Synthesis • Petasis Reaction • Peterson Olefination • Pictet-Spengler Tetrahydroisoquinoline Synthesis • Preparation of Aldehydes and Ketones • Preparation of Alkylbenzene • Preparation of Amines • Prins Reaction • Reactions of Aldehydes and Ketones • Reactions of Alkyl Halides with Reducing Metals • Reactions of Amines • Reactions of Benzene and Substituted Benzenes • Reactions of Dihalides • Reformatsky Reaction • Reimer-Tiemann Reaction • Robinson Annulation • Schlosser Modification of the Wittig Reaction • Schmidt Reaction • Specialized Acylation Reagents-Ketenes • Stille Coupling • Stobbe Condensation • Substitution and Elimination Reactions of Alkyl Halides • Suzuki Coupling • Tebbe Olefination • Ugi Reaction • Vilsmeier-Haack Reaction • Wittig Reaction • Wolff-Kishner Reduction

Categories

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