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Chemical Structure| 1413615-86-7 Chemical Structure| 1413615-86-7

Structure of 1413615-86-7

Chemical Structure| 1413615-86-7

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Product Details of [ 1413615-86-7 ]

CAS No. :1413615-86-7
Formula : C22H14ClN3
M.W : 355.82
SMILES Code : ClC1=NC=CC(C2=CC(N3C4=C(C5=C3C=CC=C5)C=CC=C4)=CC=C2)=N1

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Application In Synthesis of [ 1413615-86-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1413615-86-7 ]

[ 1413615-86-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 1255308-97-4 ]
  • [ 1413615-86-7 ]
  • [ 1419577-09-5 ]
YieldReaction ConditionsOperation in experiment
30% After dissolving NaH 60 % (0.9 g, 0.02 mol) in DMF (50 mL), the solution was stirred. After dissolving compound 2-2 (4.69 g, 0.017 mol) in DMF (20 mL), the solution was added to the NaH solution, and was stirred for 1 hour. After dissolving compound 1-3 (6.1 g, 0.017 mol) in DMF (100 mL), the solution was stirred. And then, the mixed solution of compound 2-2 was added to the mixed solution of compound 1-3, and was stirred for 12 hours. After terminating the reaction, the obtained yellow solid was filtered, and was recrystallized to obtain compound C-94 (3 g, 30 %).[109]MS/FAB found 593; calculated 592.71
  • 2
  • [ 1257220-47-5 ]
  • [ 1413615-86-7 ]
  • [ 1419576-90-1 ]
YieldReaction ConditionsOperation in experiment
36% After dissolving compound 1-2 (6.6 g, 18.6 mmol) in DMF (120 mL), NaH (813 mg, 20.3 mmol) was added at 0C, and was stirred for 10 minutes. Compound 1-3 (4.8 g, 16.9 mmol) was added to the reaction mixture, and was stirred for 19 hours. After terminating the reaction, MeOH was added to the reaction mixture. The obtained solid was filtered through silica gel, was recrystallized with DMF to obtain compound C-40 (4 g, 36 %).[99]MS/FAB found 603; calculated 602.73
 

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