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Chemical Structure| 1393176-03-8 Chemical Structure| 1393176-03-8

Structure of 1393176-03-8

Chemical Structure| 1393176-03-8

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Product Details of [ 1393176-03-8 ]

CAS No. :1393176-03-8
Formula : C15H15N3
M.W : 237.30
SMILES Code : C[C@H](N)C1=NC2=CC=CC=C2N1C3=CC=CC=C3
MDL No. :MFCD22574116

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Application In Synthesis of [ 1393176-03-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1393176-03-8 ]

[ 1393176-03-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1393176-03-8 ]
  • [ 92001-52-0 ]
  • [ 1393180-99-8 ]
YieldReaction ConditionsOperation in experiment
30% With N-ethyl-N,N-diisopropylamine; In butan-1-ol; at 130.0℃; Step 2: A solution of (1S)-1-(1-phenyl-1H-1,3-benzodiazol-2-yl)ethan-1-amine from Example 4 (150 mg, 0.62 mmol, 1.00 equiv, 98%), <strong>[92001-52-0]6-chloro-8-methyl-9H-purine</strong> (150 mg, 0.87 mmol, 1.41 equiv) and ethylbis(propan-2-yl)amine (0.3 mL, 98%) in butan-1-ol (6 mL) was stirred overnight at 130 C. The resulting mixture was concentrated under vacuum. The residue was purified on a C18 column eluted with water/acetonitrile to give 75 mg (30%) of 158 as a white solid. LC-MS (ES, m/z) 370 [M+H]+. H-NMR (300 MHz CD3OD, ppm) delta 8.04 (s, 1H), 7.69 (d, 1H), 7.55 (m, 5H), 7.30 (m, 2H), 7.11 (d, 1H), 5.63 (s, 1H), 2.55 (s, 3H), 1.71 (d, 3H)
 

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