Home Cart Sign in  
Chemical Structure| 135689-93-9 Chemical Structure| 135689-93-9

Structure of 135689-93-9

Chemical Structure| 135689-93-9

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 135689-93-9 ]

CAS No. :135689-93-9
Formula : C14H9NO
M.W : 207.23
SMILES Code : N#CC1=CC=CC=C1C2=CC=C(C=O)C=C2
MDL No. :MFCD05979418
InChI Key :GOMLISZHRJBRGK-UHFFFAOYSA-N
Pubchem ID :1394062

Safety of [ 135689-93-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H312-H315-H319-H332-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 135689-93-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 135689-93-9 ]

[ 135689-93-9 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 1122-91-4 ]
  • [ 214360-47-1 ]
  • [ 135689-93-9 ]
  • 2
  • [ 209911-63-7 ]
  • [ 114772-54-2 ]
  • [ 135689-93-9 ]
YieldReaction ConditionsOperation in experiment
78% With hexamethylenetetramine; acetic acid; In water; chlorobenzene; at 85 - 90℃; for 12h;Product distribution / selectivity; (2) To monochlorobenzene (720 g) was added water (420 g), acetic acid (662 g) and hexamethylenetetramine (653 g, 4.66 mol), then, the whole amount of the brominated reaction solution of CMB obtained above was added, and the above-mentioned reaction vessel was washed with monochlorobenzene (120 g), and the washing solution was added to the reaction solution. The resulting solution was stirred at about 90C for 11 hours. The stirred solution was allowed to stand still at 85 to 90C for 1 hour, and aqueous layer was separated and removed. To organic layer was added water (840 ml), pH was adjusted to 7.8 with 10% potassium carbonate aqueous solution (540g), and the solution was allowed to stand still. Aqueous layer was separated and removed, then, 150 ml of monochlorobenzene was distilled off under a reduced pressure of 40 to 50 kPa at 85 to 90C. The resulting solution was cooled to 75C, seed crystals were added, then, the mixture was stirred at the same temperature for 2 hours. The mixture was cooled at a rate of 10C/hour, and aged at 8 to 12C for 6 hours. Filtration was performed, and the resulting crystals were washed with monochlorobenzene (420 g) cooled to about 5C, and dried at about 60C to obtain CBAL (250.9 g). The yield was 78%.
  • 3
  • CH2 Cl2 -MeOH [ No CAS ]
  • [ 51498-33-0 ]
  • [ 135689-93-9 ]
  • [ 137864-30-3 ]
YieldReaction ConditionsOperation in experiment
a) Ethyl cis-4-[(2'-cyanobiphenyl-4-yl)methylamino]cyclohexane-1-carboxylate is obtained from 4.145 g of 2'-cyanobiphenyl-4-carbaldehyde and 5.137 g of ethyl 4-aminocyclohexane-1-carboxylate analogously to Example 1b) and purified on silica gel 60 (40-63 mum) using CH2 Cl2 -MeOH 99.5:0.5, Rf =0.18 (system N6).
  • 4
  • [ 15862-94-9 ]
  • [ 135689-93-9 ]
  • 4'-(2-(4,5-dimethoxy-2-nitrophenyl)-1-hydroxyethyl)[1,1'-biphenyl]-2-carbonitrile [ No CAS ]
YieldReaction ConditionsOperation in experiment
51% General procedure: To a glass vessel capable of being sealed with Teflon cap (for microwave vials) were added 1 and benzaldehyde derivative (3 equiv.). The vessel was capped and then, evacuated and backfilled with N2 (process repeated 3X). Anhydrous DMF (3.5mL/mmol) was introduced and the solution was vigorously stirred for 20min at-20C. TDAE was added slowly and the mixture was stirred for 1h. Then, the reaction was stirred at room temperature overnight. After LC-MS analysis clearly showed that the chloride had been totally consumed, the reaction was hydrolysed with distilled water. The mixture was then extracted with dichloromethane. The combined organic layers were washed with water and brine, dried over Na2SO4, filtered off and concentrated under reduced pressure to afford the corresponding crude product 3.
 

Historical Records

Technical Information

Categories

Related Functional Groups of
[ 135689-93-9 ]

Aryls

Chemical Structure| 400744-71-0

A502413 [400744-71-0]

3'-Formyl-[1,1'-biphenyl]-2-carbonitrile

Similarity: 1.00

Chemical Structure| 25460-07-5

A149543 [25460-07-5]

2'-Formyl-[1,1'-biphenyl]-2-carbonitrile

Similarity: 0.97

Chemical Structure| 223575-89-1

A938265 [223575-89-1]

2'-Formyl-[1,1'-biphenyl]-3-carbonitrile

Similarity: 0.94

Chemical Structure| 199939-26-9

A427130 [199939-26-9]

2'-Formyl-[1,1'-biphenyl]-4-carbonitrile

Similarity: 0.94

Chemical Structure| 230647-84-4

A701862 [230647-84-4]

4'-Formyl-[1,1'-biphenyl]-3-carbonitrile

Similarity: 0.87

Aldehydes

Chemical Structure| 400744-71-0

A502413 [400744-71-0]

3'-Formyl-[1,1'-biphenyl]-2-carbonitrile

Similarity: 1.00

Chemical Structure| 25460-07-5

A149543 [25460-07-5]

2'-Formyl-[1,1'-biphenyl]-2-carbonitrile

Similarity: 0.97

Chemical Structure| 223575-89-1

A938265 [223575-89-1]

2'-Formyl-[1,1'-biphenyl]-3-carbonitrile

Similarity: 0.94

Chemical Structure| 199939-26-9

A427130 [199939-26-9]

2'-Formyl-[1,1'-biphenyl]-4-carbonitrile

Similarity: 0.94

Chemical Structure| 230647-84-4

A701862 [230647-84-4]

4'-Formyl-[1,1'-biphenyl]-3-carbonitrile

Similarity: 0.87

Nitriles

Chemical Structure| 400744-71-0

A502413 [400744-71-0]

3'-Formyl-[1,1'-biphenyl]-2-carbonitrile

Similarity: 1.00

Chemical Structure| 25460-07-5

A149543 [25460-07-5]

2'-Formyl-[1,1'-biphenyl]-2-carbonitrile

Similarity: 0.97

Chemical Structure| 223575-89-1

A938265 [223575-89-1]

2'-Formyl-[1,1'-biphenyl]-3-carbonitrile

Similarity: 0.94

Chemical Structure| 199939-26-9

A427130 [199939-26-9]

2'-Formyl-[1,1'-biphenyl]-4-carbonitrile

Similarity: 0.94

Chemical Structure| 230647-84-4

A701862 [230647-84-4]

4'-Formyl-[1,1'-biphenyl]-3-carbonitrile

Similarity: 0.87