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Type HazMat fee for 500 gram (Estimated)
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Chemical Structure| 13531-52-7 Chemical Structure| 13531-52-7

Structure of 13531-52-7

Chemical Structure| 13531-52-7

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Product Details of [ 13531-52-7 ]

CAS No. :13531-52-7
Formula : C5H15N3
M.W : 117.19
SMILES Code : NCCCNCCN
MDL No. :MFCD00008211

Safety of [ 13531-52-7 ]

GHS Pictogram:
Signal Word:Danger
Hazard Statements:H314
Precautionary Statements:P280-P305+P351+P338-P310
Class:8
UN#:2735
Packing Group:

Application In Synthesis of [ 13531-52-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 13531-52-7 ]

[ 13531-52-7 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 6492-86-0 ]
  • [ 13531-52-7 ]
  • [ 889880-88-0 ]
  • [ 889880-36-8 ]
YieldReaction ConditionsOperation in experiment
In ethanol; at 0 - 100℃; for 2.5h; A mixture of <strong>[6492-86-0]4-amino-1,8-naphthalic anhydride</strong> (0.477 gm, 2.13 mmole), 2-aminoethyl-1,3- propanediamine (0.83 ml, 6.38 mmole) and 2.5 ml ethanol was heated from 0 C to 100 C over 30 minutes then at 100 C for 2 hours with microwave treatment. LC/MS analysis showed the reaction was complete and the products were formed in a 2: 1 ratio. The mixture was cooled, concentrated under vacuum, taken up in DMF and purified by prep. HPLC which separated the products N-aminopropylethylamine-4-amino-1,8 naphthalimide lla 1H NMR (300 MHz, CF3CO2D): delta 8.82 (IH, d, J = 7.5 Hz); 8.61 (IH, d, J = 8.4 Hz); 8.07 (IH, t, J= 8.2 Hz); 4.75 (2H, m); 3.80 (2H, m); 3.49 (2H, m); 3.41 (2H, m); 3.34 (2H, m), and N- aminoethylpropylamine-4-amino-1,8 naphthalimide lib, each in about 98% purity.
  • 2
  • [ 28170-07-2 ]
  • [ 13531-52-7 ]
  • C13H21N3O2 [ No CAS ]
  • [ 142038-97-9 ]
  • 3
  • [ 72652-32-5 ]
  • [ 13531-52-7 ]
  • 4-bromo-N-(3''-((2'''-(4'-bromo-1'H-pyrrole-2'- carboxamido)ethyl)amino)propyl)-1H-pyrrole-2-carboxamide [ No CAS ]
  • N-(2''-((3'-aminopropyl)amino)ethyl)-4-bromo-1H-pyrrole-2-carboxamide [ No CAS ]
  • N-(3'-((2''-aminoethyl)amino)propyl)-4-bromo-1H-pyrrole-2-carboxamide [ No CAS ]
YieldReaction ConditionsOperation in experiment
36%; 28%; 35% With triethylamine; In tetrahydrofuran; at 20℃; for 18h;Inert atmosphere; General procedure: the coupling of substituted pyrroles with amine for synthesis of di-pyrroleanalogues 12-19.To a solution of pyrrole 2 (2 equiv.) in dry THF at r.t., under an atmosphere of nitrogen, amine(1 equiv.) and triethylamine (4 equiv.) were added dropwise. The mixture was stirred for 18-72 h and the solvent was removed in vacuo to give the crude product, which was purified as stated.
 

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