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Chemical Structure| 1351094-46-6 Chemical Structure| 1351094-46-6

Structure of 1351094-46-6

Chemical Structure| 1351094-46-6

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Product Details of [ 1351094-46-6 ]

CAS No. :1351094-46-6
Formula : C12H23NO3
M.W : 229.32
SMILES Code : O=C(N1C(COC)CCCC1)OC(C)(C)C
MDL No. :MFCD31560526
InChI Key :UKRUSUPRQFIBBZ-UHFFFAOYSA-N
Pubchem ID :69374340

Safety of [ 1351094-46-6 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362

Application In Synthesis of [ 1351094-46-6 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Upstream synthesis route of [ 1351094-46-6 ]

[ 1351094-46-6 ] Synthesis Path-Upstream   1~1

  • 1
  • [ 1351094-46-6 ]
  • [ 688809-98-5 ]
YieldReaction ConditionsOperation in experiment
99% With hydrogenchloride In 1,4-dioxane; dichloromethane at 25℃; for 20 h; c) 2-[(methyloxy)methyl]piperidine hydrochlorideTo a solution of 1 , 1 -dimethylethyl 2-[(methyloxy)methyl]-1 -piperidinecarboxylate (464 mg, 2.02 mmol) in CH2CI2 (10 ml.) was added 4 M HCI in 1 ,4-dioxane (5.06 ml_, 20.23 mmol). The mixture was stirred at 25 °C for 20 h. The mixture was partitioned between water and CH2CI2. The aqueous solution was concentrated, azeotropically dried with toluene and further dried on a high-vacuum line for 5 h to afford the title compound (259.5 mg, 99percent) as a light yellow solid. LCMS (ES) m/z 130 (M+H)+; 1 H NMR (400 MHz, DMSO-de) δ ppm 1.39 - 1.52 (m, 2 H) 1.58 (br. s, 1 H) 1.67 - 1.81 (m, 3 H) 2.83 (br. s, 1 H) 3.17 (br. s, 2 H) 3.31 (s, 3 H) 3.46 - 3.53 (m, 2 H) 8.86 (br. s, 2 H).
References: [1] Patent: WO2011/149827, 2011, A1, . Location in patent: Page/Page column 145.
 

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