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Chemical Structure| 13341-16-7 Chemical Structure| 13341-16-7

Structure of 13341-16-7

Chemical Structure| 13341-16-7

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Product Details of [ 13341-16-7 ]

CAS No. :13341-16-7
Formula : C9H11NO2
M.W : 165.19
SMILES Code : O=C(OC)C1=CC=NC=C1CC

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Application In Synthesis of [ 13341-16-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 13341-16-7 ]

[ 13341-16-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 13341-16-7 ]
  • [ 4080-54-0 ]
YieldReaction ConditionsOperation in experiment
86% With water; sodium hydroxide; In methanol; at 20℃; for 6h; Into a lOO-mL round-bottomed flask was placed a mixture of methyl 3-ethylisonicotinate (3.30 g, 20.0 mmol, 1.00 equiv), methanol (20 mL), water (4 ml) and sodium hydroxide (1.60 g, 40.0 mmol, 2.00 equiv). The reaction mixture was stirred for 6 hours at room temperature. The pH was adjusted to a pH of approximately 4 with 2 M hydrochloric acid solution. The mixture was filtered and the filter cake was collected. This resulted in 2.60 g (86%) of 3-ethylisonicotinic acid as a white solid. LC-MS (ES) [M+l]+ m/z: 152.0.
 

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