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Chemical Structure| 1333155-97-7 Chemical Structure| 1333155-97-7

Structure of 1333155-97-7

Chemical Structure| 1333155-97-7

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Product Details of [ 1333155-97-7 ]

CAS No. :1333155-97-7
Formula : C15H15IN6O2S
M.W : 470.29
SMILES Code : NC1=C2N=C(SC3=C(I)C=C(OCO4)C4=C3)N(CCCN)C2=NC=N1
MDL No. :MFCD28992273

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Application In Synthesis of [ 1333155-97-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1333155-97-7 ]

[ 1333155-97-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1333155-97-7 ]
  • [ 72040-63-2 ]
  • [ 1418215-40-3 ]
YieldReaction ConditionsOperation in experiment
72% With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20.0℃; for 1h; 13 (16.9 mg, 0.0359 mmol), EZ-Link" NHS-LC-Biotin (17 .9 mg, 0.0394mmol) and DIEA (9.3 mg, l2.5f.IL, 0.0718 mmol) in DMF (0.5 mL) was stirred at rt for l h. Thereaction mixture was concentrated under reduced pressure and the resulting residue was purified bypreparatory TLC (CH2Cl2:MeOH-NH3 (7N), 10: I) to give 20.8 mg (72percent) ofPU-H71-biotin4. 1HNMR (500 MHz, CDC,) o 8.22 (s, H), 7.52 (t, J = 5.6 Hz, IH), 7.36 (s, H), 7.03 (s, H), 6.66 (t, J= 5.5 Hz, H), 6.25 (br s, 2H), 6.03 (s, 2H), 4.47-4.52 (m, H), 4.28-4.33 (m, H), 4.25 (t, J = 6.8 Hz,2H), 3.17-3.25 (m, 4H), 3.11-3.17 (m, IH), 2.90 (dd, J= 5.0, 12.9 Hz, H), 2.63-2.79 (m, H), 2.24 (t,J= 7.4 Hz, 2H), 2.13-2.19 (m, 2H), 1.94-2.02 (m, 2H), 1.58-1.74 (m, 6H), 1.48-1.56 (m, 2H), 1.31-1.46 (m, 4H); MS (ESI): mlz 810.3 [M+Ht.
 

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