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Chemical Structure| 131941-25-8 Chemical Structure| 131941-25-8

Structure of 131941-25-8

Chemical Structure| 131941-25-8

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Product Details of [ 131941-25-8 ]

CAS No. :131941-25-8
Formula : C12H10N2O3
M.W : 230.22
SMILES Code : COC1=CC=C(C=C1)C1=NC=C(C=C1)[N+]([O-])=O
MDL No. :MFCD06200960

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Application In Synthesis of [ 131941-25-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 131941-25-8 ]

[ 131941-25-8 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 14150-94-8 ]
  • [ 100-06-1 ]
  • [ 131941-25-8 ]
  • 2
  • [ 131941-25-8 ]
  • [ 52057-98-4 ]
YieldReaction ConditionsOperation in experiment
With 5%-palladium/activated carbon; hydrogen; In methanol; under 760.051 Torr; General procedure: The crude nitroderivative (5) from the previous step(0.75 mmol) was hydrogenated under atmospheric pressure inmethanol (50 mL) with 5% wt. palladium on charcoal (50 mg). Afterthe consumption of hydrogen, the reaction mixture was filteredthrough Celite, washed with methanol and evaporated underreduced pressure. The crude product was dissolved in 2M hydrochloricacid (50 mL) and extracted with dichloromethane (25 mL).The water phase was neutralized with 5% sodium hydrogen carbonate,and the precipitate was filtered off and washed with water.The crude product was dried in a vacuum desiccator and finallypurified by flash column chromatography using mobile phasechloroform/methanol (4:1, v/v).
 

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