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Chemical Structure| 131826-11-4 Chemical Structure| 131826-11-4

Structure of 131826-11-4

Chemical Structure| 131826-11-4

3-Isobutylaniline

CAS No.: 131826-11-4

4.5 *For Research Use Only !

Cat. No.: A712915 Purity: 97%

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Product Details of [ 131826-11-4 ]

CAS No. :131826-11-4
Formula : C10H15N
M.W : 149.23
SMILES Code : NC1=CC=CC(CC(C)C)=C1
MDL No. :MFCD11934360
InChI Key :JSOMPMRZESLPSM-UHFFFAOYSA-N
Pubchem ID :19024799

Safety of [ 131826-11-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Application In Synthesis of [ 131826-11-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 131826-11-4 ]

[ 131826-11-4 ] Synthesis Path-Downstream   1~1

  • 1
  • aqueous sodium nitrite [ No CAS ]
  • [ 131826-11-4 ]
  • [ 139155-55-8 ]
YieldReaction ConditionsOperation in experiment
With copper(I) bromide; In hydrogen bromide; Preparation 14 To a solution of 3-isobutylphenylamine (3.80 g) in 48% hydrobromic acid (10 ml) was added aqueous sodium nitrite (2.11 g, 2 ml) below 10 C. over 20 minutes. The reaction mixture was added to a solution of cuprous bromide (7.3 g) in 48% hydrobromic acid (5 ml) at 25 C. After stirred at 25 C. for 1 hour, the mixture was extracted with hexane two times. The extracts were combined, washed with water and brine, and dried over magnesium sulfate. After evaporation of the solvent, the residue was chromatographed on silica gel (150 g) eluding with hexane to give 1-bromo-3-isobutylbenzene (2.61 g) as a colorless oil. NMR (CDCl3, delta): 0.92 (6H, d, J=7.5Hz), 1.72-1.98 (1H, m), 2.43 (2H, d, J=7.5Hz), 7.00-7.22 (2H, m), 7.22-7.43 (2H, m)
 

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