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Chemical Structure| 13182-64-4 Chemical Structure| 13182-64-4

Structure of 13182-64-4

Chemical Structure| 13182-64-4

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Product Details of [ 13182-64-4 ]

CAS No. :13182-64-4
Formula : C11H12N2O
M.W : 188.23
SMILES Code : O=C1NC(C(C)C)=NC2=C1C=CC=C2
MDL No. :MFCD03216800

Safety of [ 13182-64-4 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 13182-64-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 13182-64-4 ]

[ 13182-64-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 18362-64-6 ]
  • [ 28144-70-9 ]
  • [ 13182-64-4 ]
YieldReaction ConditionsOperation in experiment
36% With iron(III) chloride hexahydrate; In water; at 100℃; for 24h;Green chemistry; General procedure: A flask was charged with 2-aminobenzamide (1a; 27.2 mg, 0.2 mmol), pentane-2,4-dione (2A;30.0 mg, 0.3 mmol), FeCl3·6H2O (10.8 mg, 0.04 mmol), and PEG-400/H2O (1.0 mL, 1:9 (v/v)).The reaction was stirred at 100 C for 24 h. When the reaction was complete monitored by TLC,the mixture was cooled to room temperature, extracted with EtOAc (3×20 mL). The combined organic phase was washed with water, dried over anhydrous Na2SO4, filtered, and concentrated under reduced pressure. The residue was purified by silica gel column chromatography to give the product 3aA (29.3 mg, 91%) as white solid.
 

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