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Chemical Structure| 1303503-70-9 Chemical Structure| 1303503-70-9

Structure of 1303503-70-9

Chemical Structure| 1303503-70-9

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Product Details of [ 1303503-70-9 ]

CAS No. :1303503-70-9
Formula : C17H11BrN2
M.W : 323.19
SMILES Code : BrC1=CC2=C(N(C3=CC=CC=C3)C4=C2C=NC=C4)C=C1

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Application In Synthesis of [ 1303503-70-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1303503-70-9 ]

[ 1303503-70-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 867044-28-8 ]
  • [ 1303503-70-9 ]
  • [ 1303503-73-2 ]
YieldReaction ConditionsOperation in experiment
53% With potassium carbonate;tetrakis(triphenylphosphine) palladium(0); In ethanol; water; toluene; for 5.5h;Inert atmosphere; Reflux; EXAMPLE 3 <Synthesis of 8-[9,10-di(naphthalen-2-yl)-anthracen-2-yl]-5-phenyl-5H-pyrido[4,3-b]indole (compound 78)> Into a nitrogen-purged reaction vessel, 2.0 g portion of the aforementioned 8-bromo-5-phenyl-5H-pyrido[4,3-b]indole obtained in Example 1, 3.5 g of 9,10-di(naphthalen-2-yl)anthracene-2-boronic acid, 0.4 g of tetrakis(triphenylphosphine) palladium, 10 ml of 2 M potassium carbonate aqueous solution, 20 ml of toluene, and 5 ml of ethanol were added and heated, and refluxed for 5.5 hours while stirring. After cooling to room temperature, 50 ml of toluene and 30 ml of water were added thereto, followed by stirring, and thereafter, the organic layer was separated. The organic layer was dehydrated using anhydrous magnesium sulfate and then concentrated under a reduced pressure, to thereby obtain a crude product. The crude product was purified by using a column chromatography (carrier: NH silica gel, eluent: toluene), to thereby obtain 2.2 g (yield 53%) of 8-[9,10-di(naphthalen-2-yl)-anthracen-2-yl]-5-phenyl-5H-pyrido[4,3-b]indole (compound 78) as a yellow powder. Structure of the thus obtained yellow powder was identified using NMR. Results of the 1H-NMR measurement are shown in . The following 32 signals of hydrogen were detected by 1H-NMR (CDCl3). delta (ppm) = 9.32 (1 H), 8.48 (1 H), 8.32 (1 H), 8.11 (2 H), 8.02 - 8.07 (5 H), 7.95 (2 H), 7.88 (1 H), 7.68 - 7.78 (5 H), 7.58 - 7.64 (7 H), 7.49 (3 H), 7.37 (1 H), 7.33 (2 H), 7.24 (1 H).
 

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