Home Cart Sign in  
Chemical Structure| 128899-30-9 Chemical Structure| 128899-30-9

Structure of 128899-30-9

Chemical Structure| 128899-30-9

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 128899-30-9 ]

CAS No. :128899-30-9
Formula : C11H23NO2Si
M.W : 229.39
SMILES Code : O=C1N[C@@H](CO[Si](C)(C(C)(C)C)C)CC1
MDL No. :MFCD10687051

Safety of [ 128899-30-9 ]

Application In Synthesis of [ 128899-30-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 128899-30-9 ]

[ 128899-30-9 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 128899-30-9 ]
  • [ 113100-86-0 ]
  • 4-{3-[2-(<i>tert</i>-butyl-dimethyl-silanyloxymethyl)-5-oxo-pyrrolidin-1-yl]-propyl}-benzoic acid methyl ester [ No CAS ]
  • 2
  • [ 128899-30-9 ]
  • [ 3290-06-0 ]
  • [ 1047668-28-9 ]
YieldReaction ConditionsOperation in experiment
21% [199] Step 1. Alkylation of 1 with A to give 2; [200] Sodium hydride (40 mg of a 60percent dispersion in oil, 1.0 mmol) was added to a solution of 1 (200 mg,0.87 mmol) in DMF (5 mL). After 30 min at room temperature, a solution of A (commercially available fromAcros Chemical, 187 mg, 0.96 mmol) in DMF (3.7 mL) was added, followed by tetrabutylammonium iodide(32 mg, 0.087 mmol). The mixture was heated at 400C for 18 h then cooled to room temperature. The mixture was partitioned between EtOAc (50 mL) and water (50 mL). The phases were separated and the aqueous phase was extracted with EtOAc (2x20 mL). The combined organic phase was washed with brine(50 mL), dried (MgSO,)), filtered and concentrated in vacuo. The crude residue was purified by flash column chromatography on 12 g silica (hexane - EtOAc, gradient) to afford 70 mg (21percent) of 2.
 

Historical Records