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Chemical Structure| 128676-85-7 Chemical Structure| 128676-85-7

Structure of 128676-85-7

Chemical Structure| 128676-85-7

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Product Details of [ 128676-85-7 ]

CAS No. :128676-85-7
Formula : C9H5ClIN
M.W : 289.50
SMILES Code : IC1=CC2=CC=CC=C2N=C1Cl
MDL No. :MFCD09999230
InChI Key :VAKSSUOSONRGPR-UHFFFAOYSA-N
Pubchem ID :14616623

Safety of [ 128676-85-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 128676-85-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 128676-85-7 ]

[ 128676-85-7 ] Synthesis Path-Downstream   1~2

  • 1
  • [ 819849-22-4 ]
  • [ 128676-85-7 ]
  • 3-(3-N,N-dimethylaminomethyl)phenyl-2-chloroquinoline [ No CAS ]
YieldReaction ConditionsOperation in experiment
88.52% With tetrakis(triphenylphosphine) palladium(0); sodium carbonate; In water; toluene; at 80.0℃; for 8.0h; 2-Chloro-3-iodoquinoline (100 mg, 0.346 mmol) was dissolved in 3 mL of toluene, Followed by Pd (PPh3) 4 (12 mg, 0.01 mmol)Aqueous solution of sodium carbonate (73 mg, 0.692 mmol) in 0.3 mL of water,<strong>[819849-22-4]3-dimethylaminomethylbenzeneboronic acid</strong> (124 mg, 0.692 mmol),The reaction mixture was stirred at 80 C for 8 hours. To the residue was added 5 mL of water and extracted with dichloromethane (10 mL * 3). The organic phases were combined and purified by column chromatography (dichloromethane / methanol 20: 1)To give 91 mg of a pale yellow oil, yield 88.52%
  • 2
  • [ 819849-22-4 ]
  • [ 128676-85-7 ]
  • 3-(3-((dimethylamino)methyl)phenyl)-2-(naphthalen-1-yloxy)quinoline [ No CAS ]
 

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[ 128676-85-7 ]

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