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Chemical Structure| 126955-75-7 Chemical Structure| 126955-75-7

Structure of 126955-75-7

Chemical Structure| 126955-75-7

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Product Details of [ 126955-75-7 ]

CAS No. :126955-75-7
Formula : C16H13N3O5
M.W : 327.29
SMILES Code : CC1=NN(C2=C(C(O)=O)C(OC)=CC=C2)C3=C1C=CC([N+]([O-])=O)=C3

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Application In Synthesis of [ 126955-75-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 126955-75-7 ]

[ 126955-75-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 6494-19-5 ]
  • [ 31786-45-5 ]
  • [ 126955-75-7 ]
YieldReaction ConditionsOperation in experiment
7.45 g (75.9%) With hydrogenchloride; potassium carbonate; In water; nitrobenzene; Step A 3-Methyl-6-nitroindazole (5.31 g), 6.93 g of 2-bromo-6-methoxybenzoic acid, 4.71 g of potassium carbonate and 0.218 g of copper (II) oxide were stirred in 60 ml of nitrobenzene at 180° C. for 50 minutes. After cooling, 300 ml of water was added to the reaction mixture, and the insoluble substance was removed by filtration. The resulting solution was washed with chloroform. The aqueous layer was decolored with active charcoal and filtered, and 40 ml of 1 N hydrochloric acid aqueous solution was added to the filtrate. The crystals precipitated were separated by filtration and dried under reduced pressure to obtain 7.45 g (75.9percent) of 1-(2-carboxy-3-methoxyphenyl)-<strong>[6494-19-5]3-methyl-6-nitroindazole</strong>.
 

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