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Chemical Structure| 1268524-71-5 Chemical Structure| 1268524-71-5
Chemical Structure| 1268524-71-5

(R)-(-)-JQ1 Enantiomer

CAS No.: 1268524-71-5

(R)-(-)-JQ1 enantiomer, the stereoisomer(+)-JQ1, showed no significant interaction with any bromodomain. (+)-JQ1 is an inhibitor for the BET which targets the BET bromodomain. The (R)-(-)-JQ1 enantiomer stereoisomer has no appreciable affinity to BET bromodomains, whereas S-enantiomer pure (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~ 50 and 90 nM, respectively.

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Cat. No.: A118771 Purity: 98%

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Product Details of (R)-(-)-JQ1 Enantiomer

CAS No. :1268524-71-5
Formula : C23H25ClN4O2S
M.W : 456.99
SMILES Code : O=C(OC(C)(C)C)C[C@@H]1C2=NN=C(C)N2C3=C(C(C)=C(C)S3)C(C4=CC=C(Cl)C=C4)=N1
MDL No. :MFCD22124456
InChI Key :DNVXATUJJDPFDM-QGZVFWFLSA-N
Pubchem ID :49871818

Safety of (R)-(-)-JQ1 Enantiomer

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302
Precautionary Statements:P280-P305+P351+P338

Related Pathways of (R)-(-)-JQ1 Enantiomer

epigenetics

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21.88mL

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2.19mL

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