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Chemical Structure| 126058-97-7 Chemical Structure| 126058-97-7

Structure of 126058-97-7

Chemical Structure| 126058-97-7

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Product Details of [ 126058-97-7 ]

CAS No. :126058-97-7
Formula : C6H5F2NO
M.W : 145.11
SMILES Code : OC1=C(F)C=C(N)C=C1F
MDL No. :MFCD03094493
Boiling Point : No data available
InChI Key :RFEOSYDHBGPXCU-UHFFFAOYSA-N
Pubchem ID :2778764

Safety of [ 126058-97-7 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P261-P305+P351+P338

Application In Synthesis of [ 126058-97-7 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 126058-97-7 ]

[ 126058-97-7 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1920-66-7 ]
  • [ 126058-97-7 ]
  • 4-((4-amino-5-nitropyrimidin-2-yl)amino)-2,6-difluorophenol [ No CAS ]
YieldReaction ConditionsOperation in experiment
58% With trifluoroacetic acid; In 2,2,2-trifluoroethanol; at 140℃; for 0.5h;Microwave irradiation; General procedure: The relevant halogenated heterocycle (1.0equiv.), substituted aniline (2.0 equiv.) and TFA (5.0 equiv.) were takenup in TFE (0.1 M) and heated under microwave irradiation conditionsat 140 C for 30 min before being concentrated in vacuo. The residuewas resuspended in EtOAc:THF (1:1, 20 mL/mmol), washed with saturatedNaHCO3 solution (20 mL/mmol), and the aqueous phase wasfurther extracted with EtOAc:THF (1:1, 3 × 15 mL/mmol). The combinedorganic extracts were washed with brine, dried (MgSO4) andconcentrated in vacuo. The resultant residue was purified via columnchromatography and/or triturated as specified to afford the desired compound.
 

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