Home Cart Sign in  
Chemical Structure| 1258327-80-8 Chemical Structure| 1258327-80-8

Structure of 1258327-80-8

Chemical Structure| 1258327-80-8

*Storage: {[sel_prStorage]}

*Shipping: {[sel_prShipping]}

,{[proInfo.pro_purity]}

4.5 *For Research Use Only !

{[proInfo.pro_purity]}
Cat. No.: {[proInfo.prAm]} Purity: {[proInfo.pro_purity]}

Change View

Size Price VIP Price

US Stock

Global Stock

In Stock
{[ item.pr_size ]} Inquiry {[ getRatePrice(item.pr_usd,item.pr_rate,item.mem_rate,item.pr_is_large_size_no_price, item.vip_usd) ]}

US Stock: ship in 0-1 business day
Global Stock: ship in 5-7 days

  • {[ item.pr_size ]}

In Stock

- +

Please Login or Create an Account to: See VIP prices and availability

US Stock: ship in 0-1 business day
Global Stock: ship in 2 weeks

  • 1-2 Day Shipping
  • High Quality
  • Technical Support
Product Citations

Alternative Products

Product Details of [ 1258327-80-8 ]

CAS No. :1258327-80-8
Formula : C7H18ClN3O2S
M.W : 243.75
SMILES Code : O=S(NCCC1CCNCC1)(N)=O.[H]Cl
MDL No. :MFCD30487796

Safety of [ 1258327-80-8 ]

Application In Synthesis of [ 1258327-80-8 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1258327-80-8 ]

[ 1258327-80-8 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1258327-80-8 ]
  • [ 13790-39-1 ]
  • [ 1174169-87-9 ]
YieldReaction ConditionsOperation in experiment
59% With potassium carbonate; In acetonitrile; at 90℃; for 16h; The piperidine salt 4 (195 mg, 0.80 mmol) was dissolved in acetonitrile (12 mL), K2CO3 (151 mg, 1.09 mmol), 4-chloro-2,6-dimethoxyquinazoline (163 mg, 0.73 mmol) was added and stirred overnight at 90 C. The solvent was removed under vacuum and the product was purified by flash column chromatography eluting using CH2Cl2/CH3OH (90:10) to afford the desired product QPS1 as a beige solid (170 mg, 59%). Mp: 156-160 C; IR (ATR, ZnSe): ν (cm-1) 3311, 2855, 1577, 1455, 1376, 1263, 861, 794; 1H NMR (500 MHz, DMSO-d6): δ (ppm) 8.51 (s, 1H), 7.20 (s, 1H), 7.10 (s, 1H), 6.50 (s, 2H), 4.14 (d, J = 13.1 Hz, 2H), 3.93 (s, 3H), 3.91 (s, 3H), 3.02 (t, J = 11.8 Hz, 2H), 2.96-2.94 (m, 2H), 1.81 (d, J = 10.9 Hz, 2H), 1.74-1.65 (m, 1H), 1.51-1.47 (m, 2H), 1.41-1.32 (m, 2H); 13C NMR (126 MHz, MeOD-d4): δ (ppm) 165.2, 156.5, 153.4, 150.1, 149.4, 112.3, 107.0, 105.0, 56.6, 56.5, 51.3, 41. 6, 37.2, 34.8, 33.2; HRMS-ESI calcd for C17H26N5O4S [M+H]+ 396.1700 found 396.1710.
 

Historical Records