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Chemical Structure| 1244041-62-0 Chemical Structure| 1244041-62-0

Structure of 1244041-62-0

Chemical Structure| 1244041-62-0

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Product Details of [ 1244041-62-0 ]

CAS No. :1244041-62-0
Formula : C13H17BN2O2S
M.W : 276.16
SMILES Code : CC1(C)OB(OC1(C)C)C1=CC=C2N=C(N)SC2=C1
MDL No. :MFCD13190219

Safety of [ 1244041-62-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319
Precautionary Statements:P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330

Application In Synthesis of [ 1244041-62-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1244041-62-0 ]

[ 1244041-62-0 ] Synthesis Path-Downstream   1~3

  • 1
  • [ 445491-71-4 ]
  • [ 1244041-62-0 ]
  • [ 1244041-68-6 ]
YieldReaction ConditionsOperation in experiment
64% With cesium fluoride;bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; at 80℃; for 12.0h; Step 4} Formation of 6-[5~(methy.supsilonffonyi)pyridin~3-yi]-1 ,3-benzothiazo.-2-amine A mixture of 6~(4>;4,5.5-tetramethyl-1,3-dioxaborolan~2-yl}~1/3~benzothiazol~2~amine (5 g, 18 mmol), 3~bromo5~(methy.suifonyi)pyridine (4.27 g, 18 mmo.), cesium fluoride (5.5 g, 36.2 mmol) and PdCi2 (PPh3J2 (0.25 gs 0.4 mmol) in DMF (25 mL) stirred at800C for 12 h. The reaction mixture was cooied RT. poured into ice water and the product was extracted with ethyl acetate (2x10OmL). The combined organic layer was dried over Na2SO4 and evaporated under vacuum. The crude product was purified by column chromatography (CHCi3ZMeOH) to afford the titie compound (3.5 g, 64%) as paie yellow solid.LC/MS, M+(ESi): 305.9. HPLC1 Rt: 5.45 min (purity 99.6%).
  • 2
  • [ 313735-62-5 ]
  • [ 1244041-62-0 ]
  • C13H14N4S [ No CAS ]
  • 3
  • [ 1244041-62-0 ]
  • [ 832735-58-7 ]
  • C14H13N3OS [ No CAS ]
 

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