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Chemical Structure| 1237534-99-4 Chemical Structure| 1237534-99-4

Structure of 1237534-99-4

Chemical Structure| 1237534-99-4

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Product Details of [ 1237534-99-4 ]

CAS No. :1237534-99-4
Formula : C11H15NO5S
M.W : 273.31
SMILES Code : O=C1O[C@@H](C)[C@H]1N.O=S(C2=CC=C(C)C=C2)(O)=O
MDL No. :MFCD27991388

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Application In Synthesis of [ 1237534-99-4 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 1237534-99-4 ]

[ 1237534-99-4 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 1659-31-0 ]
  • [ 1237534-99-4 ]
  • [ 69605-90-9 ]
  • [ 1439366-63-8 ]
YieldReaction ConditionsOperation in experiment
0.045 g Under nitrogen atmosphere, to a stirred mixture of (3S,4R)-2-methyl-4-oxo-3- oxetanylammonium toluene-4-sulfonate (0.120 g, 0.44 mmol) in dry CH2C12 (1 mL), DIPEA (0.072 mL, 0.44 mmol) was added dropwise. Subsequently, the crude mixture containing (3- phenylphenyl)-methyl-2-oxopyridine 1 -carboxylate (0.402 g, 1.32 mmol) dissolved in dry CH2C12 (2 mL) was added. The reaction mixture was stirred 15h at rt, concentrated to dryness and purified by column chromatography using a Teledyne ISCO apparatus, eluting with cyclohexane/TBME (from 100:0 to 70:30) to afford the title compound (0.045 g, 32%) as a white solid. MS (ESI) m/z: 334 [M-Na]+. 1H-NMR (DMSO-d6): delta 1.36 (d, J= 6.4, 3H), 4.88 (dq, Ji=J2= 6.3, 1H), 5.08-5.29 (m, 2H), 5.47 (dd, J= 9.3, J=6.2, 1H), 7.31-7.79 (m, 9H), 8.40 (d, J= 9.3, 1H).
 

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